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Clinical and Translational Gastro:通过肠鸣音特征可以无创性诊断肠易激综合征

2019-04-06 不详 MedSci原创

肠易激综合征(IBS)是一种常见的疾病,估计会影响全世界约11%的人口。通常,IBS的诊断需要在患者进行昂贵且有创的结肠镜检查以排除器质性疾病后确诊。因此,本项研究旨在探究新的无创的诊断测试。

背景: 
肠易激综合征(IBS)是一种常见的疾病,估计会影响全世界约11%的人口。通常,IBS的诊断需要在患者进行昂贵且有创的结肠镜检查以排除器质性疾病后确诊。因此,本项研究旨在探究新的无创的诊断测试。

方法: 
研究人员使用诊断病例对照研究,探讨了使用肠鸣音来表征IBS以便诊断使用。研究人员招募了临床诊断为IBS或健康(无症状)的参与者。我们在禁食后记录2小时的肠鸣音,然后在标准餐后记录40分钟。

结果: 
使用前31名IBS和37名健康参与者开发的模型的一次性交叉验证对IBS诊断的敏感性为90%,特异性为92%。使用接下来的15名IBS和15名健康参与者进行的独立测试表明,IBS诊断的敏感性为87%,特异性为87%。

结论: 
本项研究发明了一种新型的诊断IBS的无创诊断工具,但有效性需前瞻性试验的检测。

原始出处:
Du, Xuhao. Et al. Noninvasive Diagnosis of Irritable Bowel Syndrome via Bowel Sound Features. Clinical and Translational Gastroenterology.2019.

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    2019-09-08 bsmagic9140
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    2019-08-15 许安
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    2019-04-08 zll0628

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