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Diabetes Care:冠心病患者空腹血糖、餐后两小时血糖和HbA1c的预后价值!

2017-06-21 xing.T MedSci原创

由此可见,2h-PG,相比于FPG和HbA1c,为冠心病患者的心血管事件提供了重要的预后信息。此外,升高的2h-PG和HbA1c是增加糖尿病风险的重要预后指标。

三项检查被推荐用于确定糖代谢紊乱:即空腹血糖(FPG)、从口服葡萄糖耐量试验(OGTT)中获得的餐后2小时血糖(2h-PG)和糖化血红蛋白(HbA1c)。近日,糖尿病领域权威杂志Diabetes Care上发表了一研究文章,该研究旨在探讨这些筛查试验对冠心病患者的预后价值。研究人员采用FPG、2h-PG、HbA1c筛查了4004例无糖尿病史的冠心病患者(18-80岁)的血糖异常。在随访2年后对这些试验的预后价值进行了评估。该研究的主要终点包括心血管死亡率、非致命性心肌梗死、卒中或因心力衰竭而住院,而次要终点为糖尿病发生。共有3775例患者(94.3%)获得完整的三种血糖参数信息,其中246例(6.5%)发生了主要研究终点。无论是FPG还是HbA1c都不能预测主要研究结局,而2h-PG,分为<7.8 vs. ≥7.8 mmol/L,是主要研究结局的一个重要预测因子(风险比为1.38,95%可信区间为1.07-1.78;P=0.01)。随访期间,2609例在基线时无糖尿病的参与者中有78例(3%)发生了糖尿病。FPG在6.1和6.9mmol/L之间的并不能预测糖尿病的发生,而糖化血红蛋白在

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    2018-04-01 Smile2680
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  5. 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13:28:00 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214186, encodeId=b7fb21418668, content=继续学习。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Jun 23 07:13:17 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-25 医望无涯

    FPG在6.1和6.9mmol/L之间的并不能预测糖尿病的发生,而糖化血红蛋白在5.7-6.5%之间和2h-PG在7.8-11mmol/L之间均是显著的独立预测因子。

    0

  6. 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13:28:00 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214186, encodeId=b7fb21418668, content=继续学习。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Jun 23 07:13:17 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 1e1b8538m79(暂无匿称)

    这个讲的还是挺有意思的

    0

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13:28:00 CST 2017, time=2017-06-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=214186, encodeId=b7fb21418668, content=继续学习。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Jun 23 07:13:17 CST 2017, time=2017-06-23, status=1, ipAttribution=)]
    2017-06-23 doctorJiangchao

    继续学习。

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