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COVID-19流行期间创伤后应激障碍的患病率及危险因素

2021-12-01 小文子 MedSci原创

COVID-19流行期间,护士PTSD的患病率较高。

COVID-19流行对个体心理健康产生负面影响。研究发现,创伤后应激障碍(PTSD)、抑郁和焦虑是流行病爆发最常见的心理健康问题。发表在International Journal of Nursing Studies杂志的一项研究探索了COVID-19患者/幸存者、卫生专业人员和一般人群中PTSD的全球患病率和相关危险因素。

研究检索了数据库COVID-19流行期间创伤后应激障碍相关文献,数据分析采用logit变换随机效应模型。根据人群暴露模型分为三组:患者/幸存者、卫生专业人员和一般人群。采用了Peter法评估纳入研究中潜在的发表偏倚。

检索到4045项研究,最终纳入24个不同国家的63项研究(n=124952)。PTSD患病率的总体综合估计值为17.52%(95%CI, 13.89%-21.86%),没有发表偏倚(t=-0.22,p=0.83)。研究发现,COVID-19患者(15.45%; 95%CI, 10.59-21.99),卫生专业人员(17.23%;95% CI, 11.78-24.50)和一般人群(17.34%;95%CI, 12.21-24.03)的PTSD患病率较高。亚组分析显示,COVID-19病房医务人员(30.98%;95%CI, 16.85-49.86),护士(28.22%;95%CI, 15.83-45.10),医生(10.80%, 95%CI, 6.12-18.38),其他医务人员(7.69%, 95%CI, 4.42-12.19),欧洲(25.05%; 95%CI, 19.14-32.06),亚洲(15.50%, 95%CI, 11.29-20.92),以及使用PTSD量表(DSM-5)(30.18%; 95% CI, 25.78-34.98)的PTSD患病率较高。回归分析显示,65岁以上老年人PTSD患病率低于成年人群(-1.75; 95%CI, -3.16 ~ -0.34)。

结果显示,COVID-19患者、卫生专业人员和一般人群的PTSD患病率较高。年龄、工作单位、卫生专业人员、区域和PTSD评估工具是重要的调节变量。对于因COVID-19导致的PTSD患者需要进一步的心理支持。

原文出处:

Ninik Yunitri, Hsin Chu, et al, Global prevalence and associated risk factors of posttraumatic stress disorder during COVID-19 pandemic: A meta-analysis, International Journal of Nursing Studies, 2021, https://doi.org/10.1016/j.ijnurstu.2021.104136.

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