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PLoS Med:骑自行车远离糖尿病

2016-08-11 Seven L 译 MedSci原创

背景:无论是休闲娱乐还是上班出行,自行车都是很好的选择。本研究的目的是:探究娱乐和通勤自行车、骑车习惯的改变和2型糖尿病(T2D)风险的关系。方法:从基线的1993到1997年,纳入了来自丹麦的24623名男性和27890名女性,年龄50-65岁,没有T2D和其他慢性疾病,进行一系列的评估,包括生活方式问卷调查和自行车习惯。大约5年后,进行第二次评估,参与者完成了一份新的、最新的生活方式问卷。结果


背景:无论是休闲娱乐还是上班出行,自行车都是很好的选择。本研究的目的是:探究娱乐和通勤自行车、骑车习惯的改变和2型糖尿病(T2D)风险的关系。

方法:从基线的1993到1997年,纳入了来自丹麦的24623名男性和27890名女性,年龄50-65岁,没有T2D和其他慢性疾病,进行一系列的评估,包括生活方式问卷调查和自行车习惯。大约5年后,进行第二次评估,参与者完成了一份新的、最新的生活方式问卷。

结果:在743245.4人年随访(平均随访14.2年)过程中,发生了6779例T2D。每周总的骑自行车(休闲和通勤)时间0、1-60、61-150、151-300和>300 min的多因素校正后T2D风险HR分别为1、0.87 (0.82, 0.93)、0.83 (0.77, 0.89)、0.80 (0.74, 0.86)和0.80 (0.74, 0.87) (p-趋势 = <0.001)。

季节性分析显示,不骑自行车、只在夏季或冬季骑自行车的人和夏季冬季均骑自行车的人,多因素校正后T2D风险HR分别为1、0.88 (0.83, 0.94)和0.80 (0.76, 0.85)。

基线到第二次评估期间,不骑自行车、停止骑自行车、开始骑自行车或持续骑自行车的人,多因素校正后T2D风险HR分别为1、0.88 (0.78, 1.01)、0.80 (0.69, 0.91)和0.71 (0.65, 0.77)。

每周骑自行车去工作,骑行时间为0、1-60、61-150和>150分钟对应的多因素校正后T2D风险HR分别为1、0.72 (0.60, 0.87)、0.83 (0.69, 1.00)和0.70 (0.57, 0.85) (p-趋势 = <0.001)。

目前研究的主要限制是使用自我报告的运动数据。

结论:无论是休闲娱乐还是上班出行,自行车都是很好的选择,都可以降低糖尿病风险。不管是一直骑自行车还是生命晚期才开始,均可以降低糖尿病风险。

所以,看到本文后赶快骑起来吧,一切都不晚。

原始出处:

Rasmussen MG.et al.Associations between Recreational and Commuter Cycling, Changes in Cycling, and Type 2 Diabetes Risk: A Cohort Study of Danish Men and Women.PLoS Med. 2016 Jul 12;13(7):e1002076. doi: 10.1371/journal.pmed.1002076. eCollection 2016.

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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-09-20 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  4. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-09-12 舒心和人

    运动是预防糖尿病发生的重要因素之一,生命在于运动,让我们一起动起来

    0

  5. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  6. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-09-02 1771ae4158m

    有意思,好

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-31 李东泽

    这篇咨询不错哦,值得学习,对于临床工作和科研思路都很有帮助。

    0

  8. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-27 stead

    运动此时

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-27 stead

    运动才是种道理

    0

  10. 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Sep 11 09:36:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109905, encodeId=854d1099050f, content=有意思,好, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Fri Sep 02 22:25:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108317, encodeId=a8b910831eb9, content=这篇咨询不错哦,值得学习,对于临床工作和科研思路都很有帮助。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105344, encodeId=4e8410534496, content=运动起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160509/IMG572FCF18A71237916.jpg, createdBy=d0861720708, createdName=stead, createdTime=Sat Aug 27 07:29:00 CST 2016, time=2016-08-27, status=1, ipAttribution=)]
    2016-08-27 stead

    运动起来

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