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BMJ:别犹豫!紧急转诊也能延长肿瘤患者生存期

2015-10-16 姜英浩 译 MedSci原创

在英国,自从2000年起就为疑似肿瘤的患者开辟紧急转诊通道,但这项行动对肿瘤患者生存的

自从2000年起,英国就为疑似肿瘤的患者开辟紧急转诊通道,但这项行动对肿瘤患者生存期的获益情况仍然不甚明确。因此,在近期的BMJ杂志上,来自英国国王学院的Henrik Møller教授发表了其团队对为疑似肿瘤的患者开辟紧急转诊通道及之后肿瘤患者的死亡率之间的队列研究。

该研究对英国8049位全科医生进行了调查。并收集分析了来自国家癌症等待时间(Cancer Waiting Times )数据库、NHS Exeter数据库、国家癌症注册中心等多个数据库的数据,以分析患者的估计死亡率与他们在就诊时使用紧急转诊通道的倾向性之间的相关性。

研究共分析了2009年在英格兰境内被确诊或首次治疗的215,284例肿瘤患者,并对其随访至2013年。对测量结果的判定采用了Cox比例风险回归预估的基于任何原因的死亡的风险比。

结果显示,在4年的随访期内,受访患者共出现了91,620例死亡,其中51,606例(56 %)是发生在确诊后1年以内的。研究中使用的两种评估使用紧急转诊的倾向的方法:标准化转诊比与检测率均显示紧急转诊与死亡率的降低相关。高转诊率与高检测率的联合风险比为0.96(95 %CI:0.94-0.99),包括了16 %(34,758例)的受试人群。而使用紧急转诊最少的全科医生治疗的肿瘤患者则容易带来更高的死亡率:风险比1.07(95 %CI:1.05-1.08),包括了37 %(79,416里)的人群。这两组的对照组则为受试人群中剩余的47 %(101,110例)人口。该死亡率相关性在不同的数据分层情况下,对不同的肿瘤类型中显示出了较高的一致性(乳腺癌除外),并且结论不受数据模型中其他潜在干扰因子的影响。

因此研究人员得出了结论:利用紧急转诊通道是一项对延长生存非常有效的方式。因此他们建议那些较少使用紧急转诊通道的医师在治疗肿瘤患者时,应考虑更多地使用紧急转诊以延长患者生命。

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    2016-05-25 kalseyzl
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    2016-04-02 gaoxiaoe
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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Sun Oct 18 21:30:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378085, encodeId=580513e808538, content=<a href='/topic/show?id=c29b69004f9' target=_blank style='color:#2F92EE;'>#生存期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69004, encryptionId=c29b69004f9, topicName=生存期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424148, encodeId=d24614241486a, content=<a href='/topic/show?id=94c182929d0' target=_blank style='color:#2F92EE;'>#肿瘤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82929, encryptionId=94c182929d0, topicName=肿瘤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60943920553, createdName=lanyan20020087, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-10-19 sunlong28

    非常感谢~

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1648579, encodeId=5eff16485e919, content=<a href='/topic/show?id=afa493462ec' target=_blank style='color:#2F92EE;'>#转诊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93462, encryptionId=afa493462ec, topicName=转诊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=471123610769, createdName=kalseyzl, createdTime=Wed May 25 10:55:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932534, encodeId=5d561932534c6, content=<a href='/topic/show?id=5cd95305803' target=_blank style='color:#2F92EE;'>#患者生存#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53058, encryptionId=5cd95305803, topicName=患者生存)], attachment=null, authenticateStatus=null, 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Sun Oct 18 21:30:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378085, encodeId=580513e808538, content=<a href='/topic/show?id=c29b69004f9' target=_blank style='color:#2F92EE;'>#生存期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69004, encryptionId=c29b69004f9, topicName=生存期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424148, encodeId=d24614241486a, content=<a href='/topic/show?id=94c182929d0' target=_blank style='color:#2F92EE;'>#肿瘤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82929, encryptionId=94c182929d0, topicName=肿瘤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60943920553, createdName=lanyan20020087, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-10-19 sunlong28

    感谢分享~

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1648579, encodeId=5eff16485e919, content=<a href='/topic/show?id=afa493462ec' target=_blank style='color:#2F92EE;'>#转诊#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93462, encryptionId=afa493462ec, topicName=转诊)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=471123610769, createdName=kalseyzl, createdTime=Wed May 25 10:55:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1932534, encodeId=5d561932534c6, content=<a href='/topic/show?id=5cd95305803' target=_blank style='color:#2F92EE;'>#患者生存#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53058, encryptionId=5cd95305803, topicName=患者生存)], attachment=null, authenticateStatus=null, 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Sun Oct 18 21:30:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378085, encodeId=580513e808538, content=<a href='/topic/show?id=c29b69004f9' target=_blank style='color:#2F92EE;'>#生存期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69004, encryptionId=c29b69004f9, topicName=生存期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424148, encodeId=d24614241486a, content=<a href='/topic/show?id=94c182929d0' target=_blank style='color:#2F92EE;'>#肿瘤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82929, encryptionId=94c182929d0, topicName=肿瘤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60943920553, createdName=lanyan20020087, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-10-19 sunlong28

    赞一个~

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Sun Oct 18 21:30:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1378085, encodeId=580513e808538, content=<a href='/topic/show?id=c29b69004f9' target=_blank style='color:#2F92EE;'>#生存期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69004, encryptionId=c29b69004f9, topicName=生存期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e68e415, createdName=juliusluan78, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424148, encodeId=d24614241486a, content=<a href='/topic/show?id=94c182929d0' target=_blank style='color:#2F92EE;'>#肿瘤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82929, encryptionId=94c182929d0, topicName=肿瘤患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=60943920553, createdName=lanyan20020087, createdTime=Sun Oct 18 01:55:00 CST 2015, time=2015-10-18, status=1, ipAttribution=)]
    2015-10-19 sunlong28

    为了积分我也是拼了~

    0

  8. 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    2015-10-18 zhouxue1990

    不太明白其中的意思

    0

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