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Eur Respir J:胸膜感染成年患者合并症和预后

2019-10-06 xing.T MedSci原创

由此可见,胸膜感染患者出现合并症几率高,住院时间较长。报告的大多数数据来自高收入经济群体。需要来自低收入地区的数据,以更好地了解地区趋势,并实现未来的最佳资源供应。

胸膜感染仍然是导致死亡的重要原因。近日,呼吸疾病领域权威杂志Eur Respir J上发表了一篇研究文章,这项研究旨在调查胸膜感染患者世界范围内既往合并症和的临床结局。


研究人员对Embase和MEDLINE数据库进行了检索,确定了2000年至2017年间报告了成人胸膜感染的文献,排除了仅报道结核、真菌或肺切除术后感染的文献。两名评价者评估了20980篇文献的准入资格。


211项研究符合纳入标准,134篇文献(227898位患者,平均年龄为52.8-岁)报告了合并症和/或结局数据。大多数研究是回顾性观察队列(n=104,78%),最常见的报告区域是东亚(n=33,24%),其次是北美(n=27,20%)。 85例(50756例患者)报告了合并症。任何合并症的中位(四分位间距(IQR))百分比患病率为72%(58-83%),其中呼吸系统疾病(20%,16-32%)和心脏疾病(19%,15-27%)是报道最常见的。125篇文献(192298例患者)报告了结局数据。中位(IQR)住院时间为19天(13–27天),中位住院或30天死亡率为4%(IQR为1-11%)。在高收入经济体地区(n=100,74%),患者年龄较大(平均56.5岁 vs. 42.5岁,p<0.0001),但既往合并症的患病率、住院时间或死亡率均无显著差异。


由此可见,胸膜感染患者出现合并症几率高,住院时间较长。报告的大多数数据来自高收入经济群体。需要来自低收入地区的数据,以更好地了解地区趋势,并实现未来的最佳资源供应。 


原始出处:


Tamsin N. Cargill,et al.A systematic review of comorbidities and outcomes of adult patients with pleural infection.Eur Respir J.2019.https://erj.ersjournals.com/content/54/3/1900541


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Eur Respir J:胸膜感染患者合并症和结局

由此可见,胸膜感染患者合并症较多,住院时间较长。大多数报告的数据来自高收入地区。需要来自低收入地区的数据,以便更好地了解地区趋势,并实现最佳的资源供应。

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