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JAMA Netw Open:22年中国人群随访揭示,吸烟可使胃癌死亡风险翻倍,长期吃大蒜可起到预防作用

2020-06-30 生物探索 生物探索

胃癌是一种起源于胃黏膜上皮的恶性肿瘤,位居全球癌症死亡率的第三位。由于早期症状不明显,发现时往往已经到了晚期,因此也被称为“沉默的杀手”。每年全世界约有120万人患上这种疾病,

胃癌是一种起源于胃黏膜上皮的恶性肿瘤,位居全球癌症死亡率的第三位。由于早期症状不明显,发现时往往已经到了晚期,因此也被称为“沉默的杀手”。每年全世界约有120万人患上这种疾病,17万人因此而丧生。作为胃癌高发大国,中国每年有近50万的新发病例,占全球胃癌新发病例的40%以上。

自1995年起,北京大学肿瘤医院的一支研究团队就开始探索生活方式与胃癌发病率及死亡率之间的关联,并寻找阻止这一“杀手”的有效方法。当地时间6月26日,该团队在《JAMA Network Open》在线发表了最新研究成果。他们发现,与饮酒相比,吸烟是增加胃癌发生率和死亡率风险的重要因素,不吸烟的人群可以通过吃大蒜起到预防作用。

doi:10.1001/jamanetworkopen.2020.6628

这是一项在山东省临朐县进行的隐蔽、随机、安慰剂对照试验,该县是胃癌高风险地区。1995年7月至2017年12月期间,共有3365名年龄在35至64岁之间的村民参与了试验,平均年龄为47.1岁,女性占比为48.7%。随访期间,151人患有胃癌,94人死于该疾病。

该研究的主要结果是评估生活方式、补充维生素和大蒜补充剂对胃癌发生率和死亡率的影响,次要结果是探索1995年至2003年期间参与者的胃部病变进展情况。

分析结果表明,吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。这种关联在幽门螺杆菌阳性的参与者中更为显著,其胃癌发生率增加了88%,死亡率增加了115%。饮酒以及饮食因素与胃癌之间的相关性并不明显。

生活方式因素与胃癌发病率和死亡率之间的关联

对生活方式和营养补充剂的进一步分析表明,吸烟以及饮食方式并不会显著影响维生素补充剂对胃癌的预防和改善作用,但是不饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%,并且这种关联仅在幽门螺杆菌阳性的参与者中更为显著。研究人员认为,这是因为大蒜含有的烯丙基硫化合物可通过抑制致癌物的活化、调节致癌物的代谢、抑制与致癌物的DNA加合物的形成等机制起到抗癌作用。

1995年至2003年期间,42.9%的参与者出现了胃部病变。对相关数据进行分析后,研究人员发现,在新鲜蔬果摄入量较低的人群中(<81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。

总之,这项研究为生活方式干预胃癌预防提供了新的见解,表明大规模胃癌预防策略可能需要针对不同生活方式的人群进行调整,以最大限度地发挥潜在的有益效果。

原始出处:

Yang Guo, Zhe-Xuan Li, Jing-Yu Zhang, et al. Association Between Lifestyle Factors, Vitamin and Garlic Supplementation, and Gastric Cancer Outcomes A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2020;3(6):e206628.

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    2021-01-29 canlab
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    2020-12-04 feather89
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    2020-07-16 Jessica

    吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(<81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。#学习#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1734232, encodeId=6a7a1e34232c4, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Jan 29 02:45:02 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728586, encodeId=5d411e2858646, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Dec 04 02:45:02 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803018, encodeId=a9ff803018ca, content=吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(&lt;81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:06:45 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803017, encodeId=b06c80301e5e, content=看来维生素也不能瞎补充呀<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:04:33 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255997, encodeId=f986125599e96, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Jul 02 09:45:02 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036153, encodeId=5e151036153ae, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Jun 30 21:45:02 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800634, encodeId=50cf80063470, content=有些结果难以解释🟢🟢, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 21:40:38 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800617, encodeId=1a0380061e4e, content=<a href='/topic/show?id=2b7369148e5' target=_blank style='color:#2F92EE;'>#生活方式干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69148, encryptionId=2b7369148e5, topicName=生活方式干预)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 19:22:38 CST 2020, time=2020-06-30, status=1, ipAttribution=)]
    2020-07-16 Jessica

    看来维生素也不能瞎补充呀#学习#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1734232, encodeId=6a7a1e34232c4, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Jan 29 02:45:02 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728586, encodeId=5d411e2858646, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Dec 04 02:45:02 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803018, encodeId=a9ff803018ca, content=吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(&lt;81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:06:45 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803017, encodeId=b06c80301e5e, content=看来维生素也不能瞎补充呀<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:04:33 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255997, encodeId=f986125599e96, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Jul 02 09:45:02 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036153, encodeId=5e151036153ae, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Jun 30 21:45:02 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800634, encodeId=50cf80063470, content=有些结果难以解释🟢🟢, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 21:40:38 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800617, encodeId=1a0380061e4e, content=<a href='/topic/show?id=2b7369148e5' target=_blank style='color:#2F92EE;'>#生活方式干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69148, encryptionId=2b7369148e5, topicName=生活方式干预)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 19:22:38 CST 2020, time=2020-06-30, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1734232, encodeId=6a7a1e34232c4, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Jan 29 02:45:02 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728586, encodeId=5d411e2858646, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Dec 04 02:45:02 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803018, encodeId=a9ff803018ca, content=吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(&lt;81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:06:45 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803017, encodeId=b06c80301e5e, content=看来维生素也不能瞎补充呀<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:04:33 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255997, encodeId=f986125599e96, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Jul 02 09:45:02 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036153, encodeId=5e151036153ae, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Jun 30 21:45:02 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800634, encodeId=50cf80063470, content=有些结果难以解释🟢🟢, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 21:40:38 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800617, encodeId=1a0380061e4e, content=<a href='/topic/show?id=2b7369148e5' target=_blank style='color:#2F92EE;'>#生活方式干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69148, encryptionId=2b7369148e5, topicName=生活方式干预)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 19:22:38 CST 2020, time=2020-06-30, status=1, ipAttribution=)]
    2020-06-30 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1734232, encodeId=6a7a1e34232c4, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Jan 29 02:45:02 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728586, encodeId=5d411e2858646, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Dec 04 02:45:02 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803018, encodeId=a9ff803018ca, content=吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(&lt;81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:06:45 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803017, encodeId=b06c80301e5e, content=看来维生素也不能瞎补充呀<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:04:33 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255997, encodeId=f986125599e96, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Jul 02 09:45:02 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036153, encodeId=5e151036153ae, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Jun 30 21:45:02 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800634, encodeId=50cf80063470, content=有些结果难以解释🟢🟢, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 21:40:38 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800617, encodeId=1a0380061e4e, content=<a href='/topic/show?id=2b7369148e5' target=_blank style='color:#2F92EE;'>#生活方式干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69148, encryptionId=2b7369148e5, topicName=生活方式干预)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 19:22:38 CST 2020, time=2020-06-30, status=1, ipAttribution=)]
    2020-06-30 mswert122

    有些结果难以解释🟢🟢

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1734232, encodeId=6a7a1e34232c4, content=<a href='/topic/show?id=d4f412668a4' target=_blank style='color:#2F92EE;'>#NET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12668, encryptionId=d4f412668a4, topicName=NET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7ea033781210, createdName=canlab, createdTime=Fri Jan 29 02:45:02 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728586, encodeId=5d411e2858646, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Dec 04 02:45:02 CST 2020, time=2020-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803018, encodeId=a9ff803018ca, content=吸烟是胃部的头号“杀器”,使胃癌发生风险增加了72%,死亡风险则增加了惊人的101%。 饮酒的人群可通过补充大蒜使胃癌死亡风险降低67%。 研究人员发现,在新鲜蔬果摄入量较低的人群中(&lt;81 kg / y),补充维生素剂能够起到预防作用,将胃部病变风险降低20%,然而在新鲜蔬果摄入量较高的人群中(≥81kg / y),维生素剂的补充则会增加胃部病变的风险。<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:06:45 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=803017, encodeId=b06c80301e5e, content=看来维生素也不能瞎补充呀<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Jul 16 21:04:33 CST 2020, time=2020-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255997, encodeId=f986125599e96, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Jul 02 09:45:02 CST 2020, time=2020-07-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1036153, encodeId=5e151036153ae, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Jun 30 21:45:02 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800634, encodeId=50cf80063470, content=有些结果难以解释🟢🟢, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 21:40:38 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=800617, encodeId=1a0380061e4e, content=<a href='/topic/show?id=2b7369148e5' target=_blank style='color:#2F92EE;'>#生活方式干预#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69148, encryptionId=2b7369148e5, topicName=生活方式干预)], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/02/28/889a1910ded7780f3c049b354f1648b7.jpg, createdBy=2a791737770, createdName=mswert122, createdTime=Tue Jun 30 19:22:38 CST 2020, time=2020-06-30, status=1, ipAttribution=)]

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