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J Stroke Cerebrovasc Dis:缺血性卒中患者,注意心脏功能检测!

2016-05-18 崔倩 译 MedSci原创

背景:心脏骤停是急性缺血性脑卒中的严重并发症,但其发病及特点却不清楚。研究者研究了一个大型缺血性脑卒中住院人群,比较有无心脏骤停患者的特征。方法:来自加拿大的研究者研究来自安大略卒中登记处的缺血性卒中患者,这些患者2003年7月到2008年6月因缺血性卒中入住安大略11个三级医疗卒中中心,。多变量分析以确定心脏骤停独立的预测因素及相关的预后。建立校正生存曲线,确定心脏骤停和其他主要预后与30天和1

背景:心脏骤停是急性缺血性脑卒中的严重并发症,但其发病及特点却不清楚。研究者研究了一个大型缺血性脑卒中住院人群,比较有无心脏骤停患者的特征。

方法:来自加拿大的研究者研究来自安大略卒中登记处的缺血性卒中患者,这些患者2003年7月到2008年6月因缺血性卒中入住安大略11个三级医疗卒中中心。


多变量分析以确定心脏骤停独立的预测因素及相关的预后。建立校正生存曲线,确定心脏骤停和其他主要预后与30天和1年的死亡率的危险比。

结果:共9019例急性缺血性脑卒中患者,352例发生心脏骤停,总发生率为3.9%。去除姑息性治疗的患者进行敏感性分析,心脏骤停的发生率为2.5%。心脏骤停的独立预测因素为:高龄、卒中严重程度、住院前躯体依赖及糖尿病史心肌梗塞,充血性心力衰竭和心房颤动。与心脏骤停相关的全身并发症:心肌梗死、肺栓塞、脓毒症、胃肠道出血和肺炎。心脏骤停的患者在出院时残疾风险较高, 30天的死亡率显著升高,心脏骤停为82.1%,而无心脏骤停为9.3%。

结论:缺血性卒中患者心脏骤停的发生率很高,与缺血性卒中的预后不良相关,包括多个医疗并发症并且死亡率非常高。这项研究中确定的心脏骤停的预测因素可以帮助缺血性脑卒中患者心脏调查及长期的心脏监测的风险分层。

原始出处:

Joundi RA, Rabinstein AA, et al. Cardiac Arrest in Acute Ischemic Stroke: Incidence, Predisposing Factors, and Clinical Outcomes. J Stroke Cerebrovasc Dis. 2016 Apr 7.

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    2016-09-28 quxin068
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    2016-05-29 hb2008ye
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