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Stroke:小脑出血的位置可以提示病变性质!

2017-12-01 xing.T MedSci原创

该研究的结果表明,浅表性小脑ICH与脑叶CMB相关,其为病理证实的脑淀粉样血管病标志。小脑血肿的位置可以帮助识别那些可能有脑淀粉样血管病病理的患者。

自发性小脑出血(ICH)主要与继发于高血压血管改变有关。然而,小脑出血亚组似乎于血管淀粉样蛋白沉积相关(脑淀粉样血管病)。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员试图确定小脑内血肿部位(深、浅区)是否提示特定的易出血的小血管病(脑淀粉样血管病和高血压血管病变)。

研究人员从一个三级医疗中心招募了小脑出血患者。基于病理报告的数据,患者被根据小脑原发血肿的位置(深部与浅部)进行分型。研究人员通过磁共振成像来评估脑微出血的位置(CMBs;脑叶、深部和混合CMB)。

深部小脑血肿患者有一百零八例(84%),浅表小脑血肿20例(16%)。深部小脑出血比浅表性小脑出血更常见(分别为89%和65%,P<0.05)。在进行磁共振成像的患者中,浅表性小脑ICH的患者脑叶性CMB(43%)的患病率较高,并且深部或混合型CMB患病率较低(0%),相比于那些深部小脑ICH的患者(分别为6%,17%和38%)。在多变量模型中,脑叶CMB与浅表性小脑ICH相关(比值比为3.8,95%可信区间为1.5-8.5,P=0.004)。

该研究的结果表明,浅表性小脑ICH与脑叶CMB相关,其为病理证实的脑淀粉样血管病标志。小脑血肿的位置可以帮助识别那些可能有脑淀粉样血管病病理的患者。

原始出处:

Marco Pasi, et al. Cerebellar Hematoma Location Implications for the Underlying Microangiopathy.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.019286

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    2017-12-06 半夏微凉

    学习了谢谢分享

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    2017-12-03 huangdf
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    2017-12-03 1209e435m98(暂无昵称)

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    2017-12-01 1e145228m78(暂无匿称)

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