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Obesity Rev:英研究称用腰围身高比预测肥胖风险更精准

2012-05-24 曹淑芬 中国科学报

人们通常都使用身体质量指数(BMI)评估健康风险。不过,近日,一项英国研究显示,使用“腰围身高比”能更精准地评估肥胖带来的健康风险。相关研究成果刊登在了国际杂志Obesity Reviews上。 BMI值以身高、体重作为计算标准,可以帮助确认一个人的体重是正常的,还是过轻、过重。但从BMI值无法看出其他潜在危险,仅靠BMI值,很容易导致错误判断。例如,从BMI值看不出肌肉质量,有些人肌肉

人们通常都使用身体质量指数(BMI)评估健康风险。不过,近日,一项英国研究显示,使用“腰围身高比”能更精准地评估肥胖带来的健康风险。相关研究成果刊登在了国际杂志Obesity Reviews上。
 
BMI值以身高、体重作为计算标准,可以帮助确认一个人的体重是正常的,还是过轻、过重。但从BMI值无法看出其他潜在危险,仅靠BMI值,很容易导致错误判断。例如,从BMI值看不出肌肉质量,有些人肌肉比较多,这些人很可能就被错误归类到肥胖族群。
 
研究人员对共有30万名男女参与的31项研究报告进行了评估。研究结果发现,“腰围身高比”比BMI值,以及单纯的腰围数字更能精确预测高血压、糖尿病和心脏病等与肥胖相关的疾病风险。
 
由英国伦敦城市大学卡斯商学院所进行的这项研究称,对一位30岁没有吸烟习惯的男性来说,如果腰围数字占身高一半以上,其寿命最多会缩短14%。研究人员建议,人们应尽量将腰围数字控制在身高一半以下,这样有助于延长人的寿命。(生物谷Bioon.com)

doi:10.1111/j.1467-789X.2011.00952.x
PMC:
PMID:

Waist-to-height ratio is a better screening tool than waist circumference and BMI for adult cardiometabolic risk factors: systematic review and meta-analysis

M. Ashwell1,3,*, P. Gunn2, S. Gibson2

Our aim was to differentiate the screening potential of waist-to-height ratio (WHtR) and waist circumference (WC) for adult cardiometabolic risk in people of different nationalities and to compare both with body mass index (BMI). We undertook a systematic review and meta-analysis of studies that used receiver operating characteristics (ROC) curves for assessing the discriminatory power of anthropometric indices in distinguishing adults with hypertension, type-2 diabetes, dyslipidaemia, metabolic syndrome and general cardiovascular outcomes (CVD). Thirty one papers met the inclusion criteria. Using data on all outcomes, averaged within study group, WHtR had significantly greater discriminatory power compared with BMI. Compared with BMI, WC improved discrimination of adverse outcomes by 3% (P < 0.05) and WHtR improved discrimination by 4–5% over BMI (P < 0.01). Most importantly, statistical analysis of the within-study difference in AUC showed WHtR to be significantly better than WC for diabetes, hypertension, CVD and all outcomes (P < 0.005) in men and women. For the first time, robust statistical evidence from studies involving more than 300 000 adults in several ethnic groups, shows the superiority of WHtR over WC and BMI for detecting cardiometabolic risk factors in both sexes. Waist-to-height ratio should therefore be considered as a screening tool.

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    2012-09-17 智慧医人
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    2012-05-26 naiwu77
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    2012-05-26 lingaifan
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    2012-05-26 skhzy

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人类多能胚胎干细胞 近日,纽约干细胞研究中心(NYSCF)的研究者表示,人类的胚胎干细胞可以分化成骨组织用以进行移植研究以及潜在的治疗方法,这项研究刊登在了5月14日的国际杂志PNAS上,文章中,研究者第一次使用源于胚胎干细胞的骨细胞祖细胞来大量生成紧凑的骨组织用以修复厘米大小的缺陷。 当将祖细胞植入小鼠体内后,植入的骨组织支持血管再生,并且使得正常的骨结构继续发育,而且没有任何肿瘤生长的可能

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近日,来自利兹大学的研究者发现了由神经细胞信号传导引起的疼痛机制,这项研究解释了为什么很多止痛药目前对机体失去作用,以及为未来新的止痛药开发提供了线索。Nikita Gamper教授领导的研究小组调查了持续性痛(如牙痛)和增加的神经敏感性痛(由伤和疾病引起,如痛觉过敏)之间的区别。相关研究成果刊登在了5月14日的国际杂志PNAS上,研究者发现,这两种疼痛都来源于同一种神经,但是确实通过不同机制来产

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