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Diabetes Care:青少年1型糖尿病患者糖尿病相关健康生活质量的相关因素分析!

2017-05-26 xing.T MedSci原创

在所有三个年龄组中,HbA1c越低,D-HRQOL越好,强调在全球青少年和年轻成人样本中更好的D-HRQOL和最佳血糖控制之间的很强的相关性。三种糖尿病管理行为也与最佳血糖控制有关,这提示它们是提高D-HRQOL以及血糖控制临床干预的可能调节因素。

近日,糖尿病领域权威杂志Diabetes Care上发表了一研究文章,研究人员旨在描述患有1型糖尿病(T1DM)的青少年和年轻成年人全球样本的糖尿病特异性健康相关生命质量(D-HRQOL),并识别与生活质量相关的主要因素。

TEENs研究是一个国际性的在年龄为8-25岁的TIDM青少年中进行的横断面研究。该研究的参与者(n=5887)来自于5个大洲的20个国家的临床机构,预先设定了3个年龄组:8-12岁、13-18岁,和19-25岁。为了评估D-HRQOL,参与者完成了PedsQL 糖尿病模块3.0,并被采访了家庭因素。研究人员从病例中收集了治疗方案和自我管理行为的细节。

在所有年龄组中,女性报告的D-HRQOL比男性显著降低。19-25岁年龄组报道的D-HRQOL最低。多元线性回归分析显示,D-HRQOL与HbA1c水平显著相关;HbA1c水平越低,D-HRQOL越好。三种糖尿病管理行为与更好的D-HRQOL显著相关:先进的方法用于测量食物的摄入;更频繁的每日血糖监测;青年人每周身体活动超过30分钟的天数越多。

在所有三个年龄组中,HbA1c越低,D-HRQOL越好,强调在全球青少年和年轻成人样本中更好的D-HRQOL和最佳血糖控制之间的很强的相关性。三种糖尿病管理行为也与最佳血糖控制有关,这提示它们是提高D-HRQOL以及血糖控制临床干预的可能调节因素。

原始出处:

Barbara J. Anderson, et al. Factors Associated With Diabetes-Specific Health-Related Quality of Life in Youth With Type 1 Diabetes: The Global TEENs Study.Diabetes Care.2017.https://doi.org/10.2337/dc16-1990

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  5. 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  6. 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GetPortalCommentsPageByObjectIdResponse(id=202827, encodeId=d50020282e05, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri May 26 15:45:39 CST 2017, time=2017-05-26, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1901657, encodeId=d797190165e4c, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Mar 07 06:41:00 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637764, encodeId=db78163e76416, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, 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    2017-05-27 1e0f8808m18(暂无匿称)

    糖尿病研究,学习了。

    0

  9. 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    2017-05-26 狼毒花1982

    学习了感谢分享

    0

  10. 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    2017-05-26 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0

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1型糖尿病患者(T1DM)有很高的心血管事件发生的风险。    这项研究的目的是探讨术前血红蛋白A1c(HbA1c)水平能否预测冠状动脉旁路移植术(CABG)后心血管或死亡事件。    这是一个全国性的,以人口为基础的观察性队列研究,这些患者是在瑞典1997年至2012年间所有的初次接受单独的非紧急CABG的T1DM患者,患者信息来自于瑞

Diabetologia:白蛋白尿或可预测T1DM早期心功能异常

心力衰竭是1型糖尿病患者死亡的主要原因之一。因此,心力衰竭早期诊断对1型糖尿病至关重要。 为此,来自丹麦Steno糖尿病中心的Jensen教授及其团队进行了一项研究,试图确定在没有已知心脏病的1型糖尿病患者中,亚临床心脏收缩和舒张功能受损相关的患病率和临床特征。该研究结果发表在2014年04月的Diabetologia杂志上。 该研究是一项横断面调查,从Steno糖尿病中心随机选择了1093例

JCEM:1型糖尿病伴超重患者的肝脏脂肪含量及肝脏胰岛素敏感性研究

研究背景:1型糖尿病患者缺乏胰岛素在肝门静脉与外周之间的浓度梯度,这可能减弱胰岛素对肝脏脂质合成的刺激作用及对抗非酒精性脂肪性肝病(NAFLD)发展的保护作用。我们比较了1型糖尿病伴超重患者与非糖尿病患者的肝脏脂肪含量、肝糖合成及脂质分解的胰岛素敏感性。材料与方法:我们对年龄、BMI及性别匹配的32名超重1型糖尿病成人患者与32名非糖尿病患者进行比较。使用质子磁共振核磁波谱(1H-MRS)分析肝脏

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