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一杯血尿暗藏杀机

2019-06-01 何燕 检验医学网

忙碌一天,终于等到快下班了,还有5分钟……又来个尿常规。一位老妪拿着半杯鲜红的尿液缓缓走来,我立马做干化学。

忙碌一天,终于等到快下班了,还有5分钟……又来个尿常规。一位老妪拿着半杯鲜红的尿液缓缓走来,我立马做干化学。

WBC+1,蛋白+2,RBC+3,其余正常。

心想着快下班了,明显血尿,镜检省了吧,转念一想还是看看,也不差那一会儿下班。不看不知道,一看不淡定了……怎会如此多奇怪的细胞?如图:



难道是癌细胞?心中充满疑惑。如此情况病人大多会住院治疗,故而先发常规报告随后交代夜班同事瑞氏染色,如下图:



虽然直接染色杂质较多,但是仍然可以看出非正常细胞脱落细胞。

不久病人办理入院后同事电话询问临床病人情况,怀疑膀胱癌。

次日上班查看病人病例,“血尿半年余,尿痛2月,B超膀胱实质性病变,膀胱癌可能性大;腹部增强CT,膀胱占位—膀胱癌”。估计这正是血尿里为何会出现非正常脱落细胞的原因。可惜还没来得及嘱病人重新留尿看清这些细胞,病人住院一天出院。

庆幸的是,十天后病人再次入院,留取尿常规及培养。尿液还是发现异常脱落细胞,如下图:



瑞氏染色,选取片尾处观片,细胞大小不一,有红细胞吞噬现象,核大而深染,胞浆增多且有泡沫样改变,如下图:



笔者请教了上级专业老师,有核异质改变,但尿液的脱落细胞易肿胀破碎,需结合临床资料才可判定癌细胞。

几日后,病人膀胱活检病理结果,“(膀胱)高级别乳头状尿路上皮癌”。综合上述检查结果及临床表现,癌细胞明确。

经过此事,我更深切体会到体液检验虽然简单不起眼,没有高大上的感觉,但只要用心去挖掘和发现,你一定会有意外的收获。

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    2019-06-03 123592b0m72暂无昵称

    谢谢分享

    0

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    2019-06-02 quxin068
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    2019-06-01 133d9d3cm85暂无昵称

    一般肉眼血尿都不复查了,做一个用心的检验人

    0

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    2019-06-01 flysky120

    血尿

    0

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    2019-06-01 医者仁心5538

    学习了

    0

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