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Northsea Therapeutics融资4000万美元开发鱼油衍生物,治疗非酒精性脂肪性肝炎

2020-01-09 不详 MedSci原创

荷兰生物技术公司Northsea Therapeutics成功筹集了4000万美元(合3600万欧元),用于开发鱼油衍生物以治疗非酒精性脂肪性肝炎(NASH)。

荷兰生物技术公司Northsea Therapeutics成功筹集了4000万美元(合3600万欧元),用于开发鱼油衍生物以治疗非酒精性脂肪性肝炎(NASH)。

美国投资者venBio Partners领导的B轮融资,将用于完成Northsea的主要候选药物icosabutate的2b ICONA临床研究。icosabutate一种脂肪酸,可调节肝脂质、炎症和纤维化。

ICONA研究是一项随机设计264位患者的研究计划,在患者群体中以300毫克和600毫克两种剂量测试了icosabutate,治疗期为52周。其主要终点是治疗NASH而不使肝脏纤维化恶化。

到目前为止,还没有公司能够成功开发出治疗NASH的药物。NASH患者肝脏中脂肪堆积和纤维化,严重时会导致肝硬化和需要肝移植。

NASH的市场利润丰厚,全世界有数以百万计的NASH患者,并且没有经过批准的治疗方法。有人估计其市场潜力将达到200亿美元。

Northsea还将利用募集的资金开发另外两个用于血脂异常和与肠外营养相关肝病的omega 3候选药物。

原始出处:


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    2020-02-02 一叶知秋
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    2020-04-18 qjddjq
  4. 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topicName=null, topicId=null, topicList=[TopicDto(id=88870, encryptionId=36cf888e0ba, topicName=融资4000万美元)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4aa106, createdName=crystal0562, createdTime=Sun Feb 23 23:52:00 CST 2020, time=2020-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676537, encodeId=c0c216e653753, content=<a href='/topic/show?id=397299e19c7' target=_blank style='color:#2F92EE;'>#非酒精性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99719, encryptionId=397299e19c7, topicName=非酒精性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Nov 30 03:52:00 CST 2020, time=2020-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1738996, encodeId=a99f1e3899606, content=<a href='/topic/show?id=6e566913df' target=_blank style='color:#2F92EE;'>#ERA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6913, encryptionId=6e566913df, topicName=ERA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e36234488643, createdName=124988c7m106暂无昵称, createdTime=Wed Jan 29 07:52:00 CST 2020, time=2020-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822414, encodeId=ee901822414a4, content=<a href='/topic/show?id=4ce11028660b' target=_blank style='color:#2F92EE;'>#鱼油衍生物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102866, encryptionId=4ce11028660b, topicName=鱼油衍生物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7d40148, createdName=hyf028, createdTime=Sat Feb 29 12:52:00 CST 2020, time=2020-02-29, status=1, ipAttribution=)]
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