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Int J Oral Surg:口腔鳞状细胞癌术前测定血清C-反应蛋白的临床意义

2018-01-07 MedSci MedSci原创

C-反应蛋白(CRP)是全身炎症反应的指标。但是,术前通常不评估CRP。因此,本研究旨在评估口腔鳞癌患者术前血清CRP水平,并分析其与临床病理特征的关系。

C-反应蛋白(CRP)是全身炎症反应的指标。但是,术前通常不评估CRP。因此,本研究旨在评估口腔鳞癌患者术前血清CRP水平,并分析其与临床病理特征的关系。用CRP 试剂盒和分光光度计评估60名OSCC和30名健康对照者的CRP值。应用Mann-Whitney U检验,χ2检验,受试者工作特征(ROC)曲线分析和逻辑回归。 OSCC患者CRP范围为0.3?86 mg / L。 OSCC的CRP明显高于对照组。在70%的OSCC中见到CRP升高。 OSCC中CRP与临床淋巴结状况和淋巴结转移有关(P <0.05)。转移组 CRP明显高于未转移组。ROC曲线下面积为0.819。预测LNM的最佳临界值为CRP 8.65 mg / L,敏感度0.767,特异性0.767(P <0.05)。临界值与LNM显着相关。CRP升高可以预测LNM。CRP水平显着下降与LNM相关。 CRP可以提供分期和组织学之外的预后信息。因此,CRP可作为已知临床病理参数的补充来预测OSCC的预后。

原始出处:

S. Acharya, et al. Clinical significance of preoperative serum C-reactive protein in oral squamous cell carcinoma. International Journal of Oral and Maxillofacial Surgery. 2018 January. doi:http://dx.doi.org/10.1016/j.ijom.2017.06.017

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Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-04-22 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!

    0

  4. 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createdName=爆笑小医, createdTime=Tue Sep 25 05:59:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308206, encodeId=31b4308206a5, content=学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Sun Apr 22 11:59:05 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020328, encodeId=940620203281a, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sun Jul 01 21:59:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322634, encodeId=572b132263410, content=<a href='/topic/show?id=af3d38348b5' target=_blank style='color:#2F92EE;'>#口腔鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38348, encryptionId=af3d38348b5, topicName=口腔鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b1f500, createdName=zengjiayao, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575045, encodeId=1dc615e5045c9, content=<a href='/topic/show?id=b265388684' target=_blank style='color:#2F92EE;'>#C-反应蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3886, encryptionId=b265388684, topicName=C-反应蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab8416056084, createdName=szhvet, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276378, encodeId=50cb2e6378d5, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Jan 07 14:14:05 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-07-01 小几洁
  5. 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encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sun Jul 01 21:59:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322634, encodeId=572b132263410, content=<a href='/topic/show?id=af3d38348b5' target=_blank style='color:#2F92EE;'>#口腔鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38348, encryptionId=af3d38348b5, topicName=口腔鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b1f500, createdName=zengjiayao, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575045, encodeId=1dc615e5045c9, 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time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
  6. 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encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Sun Jul 01 21:59:00 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322634, encodeId=572b132263410, content=<a href='/topic/show?id=af3d38348b5' target=_blank style='color:#2F92EE;'>#口腔鳞状细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38348, encryptionId=af3d38348b5, topicName=口腔鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b1f500, createdName=zengjiayao, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1575045, encodeId=1dc615e5045c9, content=<a href='/topic/show?id=b265388684' target=_blank style='color:#2F92EE;'>#C-反应蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3886, encryptionId=b265388684, topicName=C-反应蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab8416056084, createdName=szhvet, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276378, encodeId=50cb2e6378d5, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Jan 07 14:14:05 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
  7. 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content=<a href='/topic/show?id=b265388684' target=_blank style='color:#2F92EE;'>#C-反应蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3886, encryptionId=b265388684, topicName=C-反应蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab8416056084, createdName=szhvet, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276378, encodeId=50cb2e6378d5, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Jan 07 14:14:05 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-01-07 1e0e5a1fm42(暂无匿称)

    henhao

    0

  8. 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content=<a href='/topic/show?id=b265388684' target=_blank style='color:#2F92EE;'>#C-反应蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3886, encryptionId=b265388684, topicName=C-反应蛋白)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab8416056084, createdName=szhvet, createdTime=Tue Jan 09 02:59:00 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276378, encodeId=50cb2e6378d5, content=henhao, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NcXNhUvfhzd2VdicMnaLeK2Im5gKx4Ucxd8Bwu6S7RG0uILBFQx5HTW2bU4VricDYlQqN20ibASSMYAeGrZrrTpy2Q/0, createdBy=7dcf1938111, createdName=1e0e5a1fm42(暂无匿称), createdTime=Sun Jan 07 14:14:05 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-01-07 xiaotao112411

    学习学习学习的

    0

  9. 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time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276348, encodeId=19d02e634836, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:32 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276347, encodeId=c8f72e634743, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-01-07 xiaotao112411

    学习学习学习的

    0

  10. 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Jan 07 12:26:29 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276346, encodeId=66242e63468d, content=学习学习学习的, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/05/dc628308c49d4aa82335673176ebb6d3.jpg, createdBy=153c1955083, createdName=xiaotao112411, createdTime=Sun Jan 07 12:26:25 CST 2018, time=2018-01-07, status=1, ipAttribution=)]
    2018-01-07 xiaotao112411

    学习学习学习的

    0

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单个细菌和微生物组成的变化与人类疾病(包括癌症)有关。为了揭示口腔菌群失调和口腔鳞状细胞癌(OSCC)之间潜在的关系,本研究从OSCC患者与解剖学相匹配的正常人群中分别获得癌变样本和健康样本进行分析。研究人员使用新一代测序技术在物种水平上对OSCC病变表面样品中的细菌进行分析,以全面研究这些样品中的细菌群落组成和功能基因。结果显示,与正常样品相比,在癌症样本中明显观察到更大的细菌多样性。与以前的研

Plos One:EB病毒感染和口腔鳞状细胞癌的风险密切相关!

EB病毒(EBV)感染与口腔鳞状细胞癌(OSCC)风险之间的相关性在不同的文献报道中是不一致的。近期,一篇发表在杂志Plos One上的文章对这一问题进行了荟萃分析。研究者们在2017年3月31日之前对英文和中文出版物的电子数据库进行了文献检索,以纳入合格的病例对照研究。使用基于异质性的固定或随机效应模型,估计合并的优势比(OR)和95%置信区间(95%CI)确定EBV感染与OSCC风险之间的关联

CLIN CANCER RES:口腔鳞状细胞癌对曲美替尼治疗的肿瘤反应

口腔鳞状细胞癌(OCSCC)中Ras/MEK/ERK通路活化很常见。CLIN CANCER RES近期发表了一篇文章,报道使用MEK抑制剂曲美替尼新辅助治疗口腔鳞状细胞癌的肿瘤反应。

Int J Oral Surg:口腔癌的治疗方式的选择:边缘或节段性切除

对于大多数口腔癌来说,手术是初步明确的治疗方式。在颌骨可能涉及的口腔癌肿瘤切除方面,最重要的是下颌骨的处理。

Int J Oral Surg:口腔癌治疗方式的选择

对于大多数口腔癌来说,手术是初步明确的治疗方式。在颌骨可能涉及的口腔癌肿瘤切除方面,最重要的是下颌骨的处理。

PLoS One:研究人员成功建立了一种可无创早期检测OSCC的方法

口腔鳞状细胞癌(OSCC)约占口腔恶性病变的90%,是世界第六大常见恶性肿瘤。若不能及时做出诊断则会导致死亡率的升高,因此,有必要开发可特异性并敏感性检测OSCC的生物标记物以提高早期发现率。流行病学调查显示,匈牙利人群是世界上OSCC发病率和死亡率最高的人群,因此,本研究旨在寻找适合匈牙利人群的唾液蛋白生物标志物。在这项研究中,研究人员先前报道了14个蛋白在OSCC患者唾液中显著升高。使用基于L

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