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UROLOGY:传统的计算机断层成像技术对尿酸结石进行准确的诊断

2018-02-23 MedSci MedSci原创

计算机断层摄影术中尿酸结石的术前测定将具有巨大的临床应用价值。研究人员试图设计一种软件算法,该算法可以应用非对比的计算机断层扫描数据来预测尿酸结石的存在。

计算机断层摄影术中尿酸结石的术前测定将具有巨大的临床应用价值。研究人员试图设计一种软件算法,该算法可以应用非对比的计算机断层扫描数据来预测尿酸结石的存在。

从研究人员的结石登记处鉴定出纯尿酸和草酸钙结石的患者。在分析中,只有4毫米以上的石头可以从最初的计算机断层扫描到最终的合成。采用半自动化的计算机算法对图像数据进行处理。平均和最大值HU,偏心(偏离圆)和峰度(peakvs flatness)是自动生成的。这些参数在几个数学模型中被检验,以预测尿酸结石的存在。

最终分析共纳入100例患者,其中52例为草酸钙,48例为尿酸结石。尿酸结石明显增大(12.2 vs 9.0 mm, p = 0.03),但草酸钙结石的平均衰减率较高(457 vs 315 HU, p = 0.001),最大衰减(918 vs 553 HU, p <0.001)。草酸钙石各轴的峰度显著升高(p <0.001)。采用衰减分布模式、平均衰减和石头大小的复合算法,总灵敏度为89%,特异度为91%,阳性预测值为91%,阴性预测值为89%,预测尿酸结石。

结论
采用传统的计算机断层扫描方法,将结石的大小、衰减强度和衰减模式结合起来,可以将尿酸结石与高敏感性、特异性的草酸钙结石区分开来。

原始出处:
Vishnu Ganesan.et al.Accurately Diagnosing Uric Acid Stones from Conventional Computerized Tomography Imaging: Development and Preliminary Assessment of a Pixel Mapping Software.UROLOGY.2018.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2019-01-09 bioon14
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    2018-02-25 梦想起航ing

    学习了.谢谢分享

    0

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    2018-02-23 忠诚向上

    好好学习一下

    0

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