BMJ：好恐怖！化疗导致指纹消失！——案例报道

2015-11-26 Mechront 译 MedSci原创

47岁男性接受奥沙利铂和卡培他滨化疗治疗，他的手掌开始出现干燥和红斑。有一天，他的手指不能解锁自己的手机！（知道或用过iPhone的人都了解“指纹识别”解锁的吧。）他的指纹消失了！！！知道掌跖感觉丧失性红斑（PPE）吗？又称手足综合症（HFS），表现为手掌-足底发红感觉异常或化疗导致的四肢末端红斑，为化疗药物引起的一种皮肤毒副作用。使用卡培他滨化疗患者PPE发生率大约为53-57%，但是导致指纹消

47岁男性接受奥沙利铂和卡培他滨化疗治疗，他的手掌开始出现干燥和红斑。有一天，他的手指不能解锁自己的手机！（知道或用过iPhone的人都了解“指纹识别”解锁的吧。）他的指纹消失了！！！

知道掌跖感觉丧失性红斑（PPE）吗？又称手足综合症（HFS），表现为手掌-足底发红感觉异常或化疗导致的四肢末端红斑，为化疗药物引起的一种皮肤毒副作用。

使用卡培他滨化疗患者PPE发生率大约为53-57%，但是导致指纹消失的案例鲜有！发生率未知！曾有案例报道拘留在美国边境的病人因PPE导致指纹消失。

因为PPE导致指纹消失会影响日常生活，凡事有指纹识别的地方均会或多或少受到影响，因此对该类患者应该告知指纹消失的可能。

原始出处：

Sara Lightowlers,Rubin Soomal,et al.Loss of fingerprints secondary to palmoplantar erythrodysesthesia in a patient on capecitabine chemotherapy.BMJ 2015;351:h6023

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评论区 (7)

#插入话题

插入图片

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2015-12-26 gous

#指纹#

79 0
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2016-06-25 gaoxiaoe

#BMJ#

66 0
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2015-11-30 tennian

什么原因

158 0
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2015-11-29 yydlt

什么原因！

121 0
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2015-11-29 三三五五

好有意思?

135 0
[GetPortalCommentsPageByObjectIdResponse(id=1668618, encodeId=bf4e1668618fc, content=<a href='/topic/show?id=8ce6564391b' target=_blank style='color:#2F92EE;'>#指纹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56439, encryptionId=8ce6564391b, topicName=指纹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dae126370631, createdName=gous, createdTime=Sat Dec 26 20:46:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847780, encodeId=c765184e78071, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jun 25 04:46:00 CST 2016, time=2016-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44169, encodeId=48da4416968, content=什么原因, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59d01634640, createdName=tennian, createdTime=Mon Nov 30 12:59:00 CST 2015, time=2015-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44093, encodeId=531044093ea, content=什么原因！, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Sun Nov 29 10:49:00 CST 2015, time=2015-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44081, encodeId=88f24408109, content=好有意思?, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Nov 29 08:53:00 CST 2015, time=2015-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44006, encodeId=81124400601, content=要提前告知噢, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=447a1666109, createdName=Jiangrf, createdTime=Sat Nov 28 03:48:00 CST 2015, time=2015-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44005, encodeId=f8104400567, content=要提前告知噢, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=447a1666109, createdName=Jiangrf, createdTime=Sat Nov 28 03:47:00 CST 2015, time=2015-11-28, status=1, ipAttribution=)]
2015-11-28 Jiangrf

要提前告知噢

23 0
[GetPortalCommentsPageByObjectIdResponse(id=1668618, encodeId=bf4e1668618fc, content=<a href='/topic/show?id=8ce6564391b' target=_blank style='color:#2F92EE;'>#指纹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56439, encryptionId=8ce6564391b, topicName=指纹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dae126370631, createdName=gous, createdTime=Sat Dec 26 20:46:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847780, encodeId=c765184e78071, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Jun 25 04:46:00 CST 2016, time=2016-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44169, encodeId=48da4416968, content=什么原因, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59d01634640, createdName=tennian, createdTime=Mon Nov 30 12:59:00 CST 2015, time=2015-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44093, encodeId=531044093ea, content=什么原因！, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCEEr4dM45RatXXGAkFCicnNYiasFiaRicicO1YWsIeTFOhgapauqib8Z8TChNB3ttVC5RqNHptDvAxA72Q/0, createdBy=a82a1611288, createdName=yydlt, createdTime=Sun Nov 29 10:49:00 CST 2015, time=2015-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44081, encodeId=88f24408109, content=好有意思?, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Nov 29 08:53:00 CST 2015, time=2015-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44006, encodeId=81124400601, content=要提前告知噢, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=447a1666109, createdName=Jiangrf, createdTime=Sat Nov 28 03:48:00 CST 2015, time=2015-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44005, encodeId=f8104400567, content=要提前告知噢, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=447a1666109, createdName=Jiangrf, createdTime=Sat Nov 28 03:47:00 CST 2015, time=2015-11-28, status=1, ipAttribution=)]
2015-11-28 Jiangrf

要提前告知噢

120 0

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