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Lancet Diabetes Endo:精准营养将为2型糖尿病的预防和管理带来哪些影响?

2018-05-11 闫盈盈,吴星 环球医学

2018年5月,发表在《Lancet Diabetes Endocrinol》的一项由美国科学家进行的综述,探讨了精准营养对2型糖尿病的预防和管理可能带来的影响。

2018年5月,发表在《Lancet Diabetes Endocrinol》的一项由美国科学家进行的综述,探讨了精准营养对2型糖尿病预防管理可能带来的影响。

精准营养旨在通过针对个体的遗传背景、代谢特征和环境暴露中的一种或组合,进行饮食干预或推荐,来预防管理慢性疾病。基因组学、代谢组学和肠道微生物组技术的最新进展为精准营养在预防和控制2型糖尿病方面提供了机遇和挑战。

营养基因组学研究已经确定了影响特定营养素摄入和代谢的遗传变异,并预测了个体对饮食干预的应答变化。代谢组学揭示了食物和营养物质消耗的代谢组指纹图谱,揭示了新的代谢途径,这些途径可能会通过饮食习惯进行改变。饮食干预已成功地改变了与食物代谢和血糖控制相关的肠道微生物群的丰度,组成和活性。此外,移动应用程序和可穿戴设备可促进膳食摄入量的实时评估,并提供可改善血糖控制和糖尿病管理的反馈。

通过将这些技术与大数据分析相结合,精准营养有可能为更有效地预防和管理2型糖尿病提供个性化的营养指导。尽管取得了这些技术进步,但在精准营养可广泛用于临床和公共卫生环境之前,还需要进行大量研究。

目前,精密营养领域面临的挑战包括:缺乏稳健和可重复的结果、组学技术的高成本、研究设计以及高维数据分析和解释中的方法学问题。需要证据来支持超越传统营养干预方法的精准营养的功效、成本效益和其他好处。

因此,应该对不切实际的高期望值进行管理,并权衡新兴精准营养与公共卫生营养策略,以改善饮食质量并预防2型糖尿病及其并发症。

原始出处:Wang DD, Hu FB. Precision nutrition for prevention and management of type 2 diabetes. Lancet Diabetes Endocrinol. 2018 May;6(5):416-426. 

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    2018-05-19 yfjms

    学习

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=1829622, encodeId=4f841829622b3, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 18 01:16:00 CST 2018, time=2018-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638604, encodeId=d020163860495, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Mar 09 09:16:00 CST 2019, time=2019-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1902051, encodeId=b8fb1902051ed, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Aug 07 18:16:00 CST 2018, time=2018-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1760677, encodeId=e36a1e606776f, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Mon Jan 21 11:16:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316459, encodeId=4f1e316459aa, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat May 19 04:43:48 CST 2018, time=2018-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1403321, encodeId=7b7014033211e, content=<a href='/topic/show?id=ebbde6353be' target=_blank style='color:#2F92EE;'>#精准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76353, encryptionId=ebbde6353be, topicName=精准)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epQX9hfEIBiaPg0e9KvLYVBCSGYydH6K6OQxBh3RaOC0TYP9HYy2v0XdHib1LFnZNU5Siak0P8oh8Aqw/132, createdBy=acd92440184, createdName=shijzhiewnjhch, createdTime=Sun May 13 07:16:00 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314549, encodeId=807b3145496b, content=学习学习.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/03/27/6f2d63c799d68129300901eb0e962dd4.jpg, createdBy=ddf12178538, createdName=小贝熊, createdTime=Sat May 12 23:29:36 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314486, encodeId=0fd931448691, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat May 12 18:10:43 CST 2018, time=2018-05-12, status=1, ipAttribution=)]
    2018-05-12 小贝熊

    学习学习.谢谢分享

    0

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    2018-05-12 惠映实验室

    学习了.谢谢分享.

    0

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