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J Nutr Biochem:绿茶对高脂饮食肝脏脂质代谢的影响。

2017-11-04 fengxiangxin MedSci原创

具有健康益处的绿茶(GT)是一种广泛消费的饮料,抗肥胖作用便是其健康益处的一个方面。然而,GT对于与肥胖相关的脂质水平的影响尚不清楚。在此研究中,作者探讨了GT对高脂饮食(HFD)诱导的肥胖小鼠肝脏脂质代谢的影响。

具有健康益处的绿茶(GT)是一种广泛消费的饮料,抗肥胖作用便是其健康益处的一个方面。然而,GT对于与肥胖相关的脂质水平的影响尚不清楚。在此研究中,作者探讨了GT对高脂饮食(HFD)诱导的肥胖小鼠肝脏脂质代谢的影响。

研究者使用超高效液相色谱四极杆飞行时间质谱串联法分别对喂食正常饮食(ND)、HFD饮食和HFD+GT饮食12周的C57BL / 6J小鼠进行脂质分析。偏最小二乘判别分析得分图显示了各组之间的差异,并显示在HFD+GT喂养小鼠中几种脂质代谢物的水平发生了改变。

与ND组相比,HFD小鼠中的溶血磷脂(LPLs)(例如溶血磷脂酰胆碱,溶血磷脂酰乙醇胺和溶血磷脂酰丝氨酸)水平降低,但是补充GT后可恢复至至正常。与这些脂质代谢物变化一致,HFD小鼠中肝溶血磷脂酰胆碱酰基转移酶2/4显著增加。

这项研究显示了与肥胖相关的脂质种类发生了异常变化,并且这些变化水平能够被GT的摄入减弱,这提示肝脏LPL水平的降低与肥胖中的炎症相关。

原始出处:

Nam M, Choi MS.et al.Effect of green tea on hepatic lipid metabolism in mice fed a high-fat diet.J Nutr Biochem. 2017 Sep 19;51:1-7. doi: 10.1016/j.jnutbio.2017.09.002.

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    2018-03-28 sunylz
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    2017-11-06 hbwxf
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    2017-11-06 pcw111
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    2017-11-04 天涯183

    非常好的文章.学习了

    0

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