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Neurology:眼-腭肌阵挛:脑干损伤的可能后果

2019-01-31 zyx整理 神经科病例撷英拾粹

61岁男性,既往有左侧小脑梗死,主诉卒中后视物成双伴头晕数月。

61岁男性,既往有左侧小脑梗死,主诉卒中后视物成双伴头晕数月。脑梗死如图所示。查体提示所有方向凝视均可见旋转性眼球震颤,左侧凝视时明显(视频1)。口部检查可见腭肌震颤(视频2)。眼-腭震颤(Oculopalatal tremor,OPT)被认为是由于红核(中脑),齿状核(小脑)和下橄榄核(延髓)之间的连接中断所致。最常见的原因是脑干梗死或出血,但也可在多发性硬化和其他炎症性疾病中观察到。OPT通常在脑干损伤几个月后较为明显。治疗可包括加巴喷丁,美金刚,苯二氮卓类药物和丙戊酸。

(图:可见累及左侧小脑半球尾部的脑梗死;受累部位对应于小脑后下动脉供血区)

(所有方向凝视均可见朝向左侧的旋转性眼球震颤,但往左侧和上方凝视时更明显;低剂量氯硝西泮可使旋转性眼球震颤的幅度和频率得到改善)

(可见软腭节律性收缩)

原始出处:Lawal O, Fisayo A. Teaching Video NeuroImages: Oculopalatal myoclonus: A possible consequence of brainstem injury. Neurology. 2018 Nov 27;91(22):e2104-e2105.

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    2019-07-26 yinhl1978
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    2019-09-17 zxl729
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