vue-cli-subapp
Baidu
map

神经科

订阅

MedSci主页 / 所有栏目 / 神经科

NeuroImage：研究工作记忆任务诱发的神经激活的新方法：PET/fMRI同步研究

2021-06-23 MedSci原创 MedSci原创

PET/fMRI同步研究
关注

该研究通过临床FDG-PET成像方案发现WM任务诱导的神经激活的证据。这些发现促进了追踪认知功能相关神经系统的专门方案的发展。

生理条件下，葡萄糖是大脑能量代谢的主要基质。因此，使用葡萄糖类似物[18F]氟脱氧葡萄糖(FDG)的正电子发射断层扫描(PET)已被证明在临床和研究环境中对活人脑中的神经能量学研究非常有用。虽然在给定的PET记录间隔期间发生的大脑FDG捕获通常表明了示踪剂循环前一间隔期间的平均脑代谢活动，但也有使用功能性FDG-PET测量代谢的瞬时变化的空间。在连续输注范式,氟- 18 -去氧葡萄糖摄取的斜率脑灌注时间的函数应该给瞬间脑代谢活动指数,可以捕获神经关联的视觉刺激或一个简单的电动机的性能任务在一个录音。另外，FDG-PET激活研究可以需要比较两个扫描过程，通常记录在不同的日子。 NeuroImage杂志最近发表文章，研究临床FDG-PET成像协议是否也可以捕获与工作记忆(WM)任务表现相关的神经活动的变化。 为了验证这一概念，该研究在健康志愿者样本中检测了FDG-PET和同时进行的功能性磁共振成像(fMRI)的混合PET/MR数据。PET图像采集在注射约100 MBq FDG后30分钟开始，WM任务在注射后约60分钟开始。重建了基线(44-60分钟p.i.)和WM任务(63- 71分钟p.

评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1691640, encodeId=7a4b16916400b, content=<a href='/topic/show?id=1a594e91229' target=_blank style='color:#2F92EE;'>#工作记忆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47912, encryptionId=1a594e91229, topicName=工作记忆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=582029274600, createdName=lvygwyt2791, createdTime=Sat Oct 30 08:45:47 CST 2021, time=2021-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903424, encodeId=4cb01903424b2, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Fri Jun 03 15:45:47 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728991, encodeId=ae061e2899134, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Aug 23 20:45:47 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331185, encodeId=90f3133118504, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Fri Jun 25 14:45:47 CST 2021, time=2021-06-25, status=1, ipAttribution=)]
    2021-10-30 lvygwyt2791

    #工作记忆#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1691640, encodeId=7a4b16916400b, content=<a href='/topic/show?id=1a594e91229' target=_blank style='color:#2F92EE;'>#工作记忆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47912, encryptionId=1a594e91229, topicName=工作记忆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=582029274600, createdName=lvygwyt2791, createdTime=Sat Oct 30 08:45:47 CST 2021, time=2021-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903424, encodeId=4cb01903424b2, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Fri Jun 03 15:45:47 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728991, encodeId=ae061e2899134, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Aug 23 20:45:47 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331185, encodeId=90f3133118504, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Fri Jun 25 14:45:47 CST 2021, time=2021-06-25, status=1, ipAttribution=)]
    2022-06-03 kord1982

    #新方法#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1691640, encodeId=7a4b16916400b, content=<a href='/topic/show?id=1a594e91229' target=_blank style='color:#2F92EE;'>#工作记忆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47912, encryptionId=1a594e91229, topicName=工作记忆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=582029274600, createdName=lvygwyt2791, createdTime=Sat Oct 30 08:45:47 CST 2021, time=2021-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903424, encodeId=4cb01903424b2, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Fri Jun 03 15:45:47 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728991, encodeId=ae061e2899134, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Aug 23 20:45:47 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331185, encodeId=90f3133118504, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Fri Jun 25 14:45:47 CST 2021, time=2021-06-25, status=1, ipAttribution=)]
    2021-08-23 feather89

    #PE#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1691640, encodeId=7a4b16916400b, content=<a href='/topic/show?id=1a594e91229' target=_blank style='color:#2F92EE;'>#工作记忆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47912, encryptionId=1a594e91229, topicName=工作记忆)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=582029274600, createdName=lvygwyt2791, createdTime=Sat Oct 30 08:45:47 CST 2021, time=2021-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1903424, encodeId=4cb01903424b2, content=<a href='/topic/show?id=e1b0583884b' target=_blank style='color:#2F92EE;'>#新方法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=58388, encryptionId=e1b0583884b, topicName=新方法)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Fri Jun 03 15:45:47 CST 2022, time=2022-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728991, encodeId=ae061e2899134, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Aug 23 20:45:47 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331185, encodeId=90f3133118504, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Fri Jun 25 14:45:47 CST 2021, time=2021-06-25, status=1, ipAttribution=)]
    2021-06-25 ms7514935887898259

    #PET#

    0

Baidu
map
Baidu
map
Baidu
map