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J Thor Oncol:超声引导针吸活检术能安全有效地诊断老年肺癌

2014-08-07 佚名 生物谷

近日,来自曼彻斯特大学的研究人员通过研究发现,对肺癌患者进行组织取样诊断检测或许仅在老年患者个体中是安全的,这就呼吁医生们需要开发一种更为准确安全的诊断技术,来保证患者的安全,当然这为医生们选择合适的疗法治疗肺癌患者也具有一定的价值,相关研究刊登于国际杂志Journal of Thoracic Oncology上。肺癌患者中有一半患者都是在70多岁时被诊断出了癌症,但是有研究却表明这些老年患者并不

近日,来自曼彻斯特大学的研究人员通过研究发现,对肺癌患者进行组织取样诊断检测或许仅在老年患者个体中是安全的,这就呼吁医生们需要开发一种更为准确安全的诊断技术,来保证患者的安全,当然这为医生们选择合适的疗法治疗肺癌患者也具有一定的价值,相关研究刊登于国际杂志Journal of Thoracic Oncology上。

肺癌患者中有一半患者都是在70多岁时被诊断出了癌症,但是有研究却表明这些老年患者并不太可能得到准确的诊断,对病人病情的准确评估是确保病人接受合适疗法的关键。检测病人是否患癌的非侵入手段已经扩展到对淋巴结的诊断,但是这无疑就限制了检测手段的敏感性,截止到目前为止获得单一组织样本的途径依然是在一般的麻醉剂的作用下获得的。

这项研究中,研究者利用了一种新型技术,即超声引导针吸活检术(EBUS-TBNA),该方法可以在患者保持清醒有意识的状态下进行,其是利用超声技术来引导采样针进入到肺部通道取样。Richard Booton博士表示,我们希望观察到这种新型技术对70岁以上患者和70岁以下患者进行检测带来的差别,以此来检测这种新型技术的安全性以及有用性。

这项新型技术对于任何年龄段的患者都具有较良好的耐受性,尤其是对80岁以上的患者,而且研究者也表示,EBUS-TBNA技术对于评估病人的肿瘤是否扩散到了淋巴结也是有用的。由于该技术可以安全地从患者机体中获得组织样本,因此其就可以帮助研究人员对肿瘤亚型进行检测,并且为每一个患者提供最为合适的疗法来治疗。

原始出处

Evison M1, Crosbie PA, Martin J, Bishop P, Doran H, Joseph L, Chaturvedi A, Barber PV, Booton R.EBUS-TBNA in elderly patients with lung cancer: safety and performance outcomes.J Thorac Oncol. 2014 Mar

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    2015-05-20 minlingfeng
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    2014-08-09 smlt2008

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近日,刊登在国际杂志Nature上的一篇研究论文中,来自华盛顿大学的研究人员在对常见肺癌的研究中发现,细胞信号路径中突变或许在肺癌肿瘤形成过程中发挥着重要作用,该研究或许为开发新型治疗肺癌的靶向疗法提供一定的研究思路和依据。 肿瘤学家Ramaswamy Govindan博士表示,这项研究中我们首次在基因组学层面从全景角度对许多肺部肿瘤样本进行了分析研究,许多研究都表明肺癌是一种非常异质性的疾病(

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近日,来自曼彻斯特大学的研究人员通过研究揭示了一种新型药物AZD3965或许可以有效治疗小细胞肺癌,小细胞肺癌是一种恶性的肺部癌症,相关研究刊登于国际杂志Clinical Cancer Research上。 癌症研究者当前在对一种疗法进行研究中发现该疗法药物可以引发肿瘤能量产生的改变,癌细胞中利用糖酵解有一种开关,而糖酵解需要较少的氧气而且可以产生乳酸盐作为副产品;特定分子比如单羧酸盐转运蛋白(

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