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ACADIA制药宣布FDA批准NUPLAZID(Pimavanserin)的新剂量和配方

2018-06-30 MedSci MedSci原创

ACADIA制药公司于2018年6月29日宣布FDA批准了NUPLAZID(pimavanserin)的新剂量和配方,以帮助治疗患有幻觉和与帕金森病精神病相关的妄想症患者

ACADIA制药公司于2018629日宣布FDA批准了NUPLAZIDpimavanserin)的新剂量和配方,以帮助治疗患有幻觉和与帕金森病精神病相关的妄想症患者。

美国食品及药物管理局(FDA)批准了的34毫克NUPLAZID胶囊制剂将为患者提供每日一次剂量,与目前两片17毫克片剂相比,大大减少了患者用药负担。另外,FDA批准10mg片剂在那些伴随接受可抑制NUPLAZID代谢的强细胞色素3A4CYP3A4)抑制剂的患者中提供了优化的较低剂量强度。

对于FDA批准NUPLAZID 34 mg胶囊和10 mg片剂,凸显了ACADIA一直致力于推进安全和有效的治疗方案,为患有幻觉和妄想的患者提供有效的治疗方案。巴特勒医院和布朗大学医学院的Joseph H. Friedman博士说:“NUPLAZID是我们治疗帕金森病幻觉和妄想的重大进步,用34mg胶囊替代两片17mg片剂为34mg每日一次的NUPLAZID给药方案提供了更简单和更直接的方法,同时还降低了帕金森病患者的总体用药负担,因为帕金森病患者通常也服用多种其他药物


原始出处:

http://www.firstwordpharma.com/node/1575720#axzz5JsCRXxz0

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    2019-05-23 30397615
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    2019-03-06 lishizhe
  6. [GetPortalCommentsPageByObjectIdResponse(id=1733575, encodeId=6ed91e3357563, content=<a href='/topic/show?id=610d1315064' target=_blank style='color:#2F92EE;'>#Nuplazid#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13150, encryptionId=610d1315064, topicName=Nuplazid)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=235033772476, createdName=30397615, createdTime=Thu May 23 10:24:00 CST 2019, time=2019-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1714789, encodeId=ca561e147893e, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Jul 22 11:24:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638660, encodeId=6d8a1638660cc, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Mar 20 03:24:00 CST 2019, time=2019-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1839603, encodeId=22b318396036a, content=<a href='/topic/show?id=341ae311ea' target=_blank style='color:#2F92EE;'>#FDA批准#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7311, encryptionId=341ae311ea, topicName=FDA批准)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Fri Jan 25 19:24:00 CST 2019, time=2019-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651923, encodeId=95901651923ca, content=<a href='/topic/show?id=3a3e1e9504' target=_blank style='color:#2F92EE;'>#ACA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1795, encryptionId=3a3e1e9504, topicName=ACA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=843c24278901, createdName=lishizhe, createdTime=Wed Mar 06 17:24:00 CST 2019, time=2019-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2077008, encodeId=71cb20e7008dc, content=<a href='/topic/show?id=8eda1e9729' target=_blank style='color:#2F92EE;'>#ACADIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1797, encryptionId=8eda1e9729, topicName=ACADIA)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqcyT7aQIuoYGGYr889lEiaOVWSfvMQ4d2oxhTMlWzEr6lPmg6pxzCVvPScSZrne4JFSyyPRCOxllQ/132, createdBy=416a2500064, createdName=ms3323097325231039, createdTime=Fri Aug 24 00:24:00 CST 2018, time=2018-08-24, status=1, ipAttribution=)]
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