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Clin Gastroenterol H:急性胰腺炎对身体生命质量的长期有害影响!

2017-06-04 xing.T MedSci原创

由此可见,在对AP住院患者进行14个月的随访中,研究人员发现了AP对这些患者身体QOL有意义的、独立的、有害的影响,相比那些没有AP的个人。需要进一步研究以确定这种损伤的持续时间,并评估可改变危险因素的效应。

目前还不清楚急性胰腺炎(AP)如何影响生活质量(QOL)。近日,消化病领域权威杂志Clinical Gastroenterology and Hepatology发表了一篇研究文章,研究人员旨在明确AP对身体和心理QOL的长期独立影响。

研究人员分析了91例在2011年至2015年期间因AP到匹兹堡大学医学中心住院的患者(平均年龄52岁;女性占54%),这些患者在出院后中位14个月(四分位距为12-16个月)内接受了电话调查。那些没有接受电话调查的患者通过定期邮寄问卷。病人回答的问题来自SF-12,并且答案并用于计算心理(MCS)和身体(PCS)部分总得分(正常≥50)。研究人员将这些受试者的QOL与年龄和性别匹配的没有AP(1:2)的个人进行了比较。研究人员采用多元回归分析也对其它协变量进行了控制。

随访时,AP患者的PCS(46.2±11.8)显著低于对照组(51.1±9.5),但MCS两组相似。对社会人口因素及医疗合并症进行调整后,PCS减少4分主要归因于AP。与低PCS相关的唯一胰腺炎相关因素是多系统器官衰竭。在随访期间,腹痛、止痛药的使用、残疾和当前吸烟也均与较低的PCS分数相关。AP的病因、疾病的严重程度(经亚特兰大分类修订)、使用营养支持、胰腺干预的性能并没有影响随访期间的QOL。

由此可见,在对AP住院患者进行14个月的随访中,研究人员发现了AP对这些患者身体QOL有意义的、独立的、有害的影响,相比那些没有AP的个人。需要进一步研究以确定这种损伤的持续时间,并评估可改变危险因素的效应。

原始出处:

Jorge D. Machicado, et al. Acute Pancreatitis has Long-term Deleterious Effect on Physical Quality of Life. Clinical gastroenterology and hepatology 2017. http://www.cghjournal.org/article/S1542-3565(17)30668-7/fulltext

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    2017-07-26 仁者大医
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content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jun 05 09:32:45 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206751, encodeId=e4f0206e51ad, content=不错的文章,值得学习,分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDcohE5MKT1FYlH69x7qib45icLgBDMANxIh0DDaZibQ2wQL6WianQKpDacEu0ibD5KC4r1PLl1uUcZlaQ/0, createdBy=19ad2070095, createdName=赵淘淘, createdTime=Mon Jun 05 08:22:28 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-08-12 孙文杰

    真的不错,大开眼界

    0

  5. 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time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-06 changjiu

    学习,谢谢分享

    0

  6. 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time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-06 1e10c84am36(暂无匿称)

    文章很好,拜读了

    0

  7. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/y1ZJaAFo7AFqm7Hn2QNVTjOpBV9mRicUEjyBqRMnLADF1oQXJGeIVCpiaY1hJVMd1C40EhFCw4LL8sCKTx8Yuvsw/132, createdBy=af0b1960284, createdName=孙文杰, createdTime=Sat Aug 12 17:45:17 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207393, encodeId=6e4620e39317, content=学习,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Tue Jun 06 19:09:05 CST 2017, time=2017-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=207325, encodeId=669e20e325a0, content=文章很好,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, 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content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jun 05 09:32:45 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206751, encodeId=e4f0206e51ad, content=不错的文章,值得学习,分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDcohE5MKT1FYlH69x7qib45icLgBDMANxIh0DDaZibQ2wQL6WianQKpDacEu0ibD5KC4r1PLl1uUcZlaQ/0, createdBy=19ad2070095, createdName=赵淘淘, createdTime=Mon Jun 05 08:22:28 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-05 半夏微凉

    学习了谢谢分享

    0

  8. 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time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-05 ylzr123

    感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!

    0

  9. 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time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-05 赵淘淘

    不错的文章,值得学习,分享了

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Jun 06 12:54:48 CST 2017, time=2017-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206815, encodeId=ad702068153f, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Mon Jun 05 10:12:21 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206783, encodeId=b34b206e832a, content=感谢小编为我们精心准备了如此精辟的精神大餐,小编辛苦了,点个赞吧!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jun 05 09:32:45 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206751, encodeId=e4f0206e51ad, content=不错的文章,值得学习,分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDcohE5MKT1FYlH69x7qib45icLgBDMANxIh0DDaZibQ2wQL6WianQKpDacEu0ibD5KC4r1PLl1uUcZlaQ/0, createdBy=19ad2070095, createdName=赵淘淘, createdTime=Mon Jun 05 08:22:28 CST 2017, time=2017-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=206626, encodeId=21642066265b, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Jun 05 00:06:09 CST 2017, time=2017-06-05, status=1, ipAttribution=)]
    2017-06-05 tanxingdoctor

    学习啦谢谢分享

    0

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