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FDA授予RLF-100（Aviptadil）快速通道资格：治疗COVID-19呼吸窘迫

2020-06-25 Allan MedSci原创

Covid-19RLF-100Aviptadil
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制药公司NeuroRx近日宣布，美国FDA已授予研究性新药RLF-100（Aviptadil）快速通道资格，用以治疗与COVID-19相关的急性肺损伤/急性呼吸窘迫综合征。

制药公司NeuroRx近日宣布，美国FDA已授予研究性新药RLF-100（Aviptadil）快速通道资格，用以治疗与COVID-19相关的急性肺损伤/急性呼吸窘迫综合征。RLF-100是一款合成型人血管活性肠肽（VIP），可减少肺部炎症并保护II型肺泡细胞，这些细胞被认为是SARS-CoV-2侵袭肺部的途径。

作为NeuroRx加入快速通道计划的一部分，FDA已要求NeuroRx提交可公开获得的患者入组政策，以便患者可以进入RLF-100（Aviptadil）的III期临床试验。

在包括迈阿密大学、休斯敦卫理公会医院、加利福尼亚大学欧文分校、纽约大学朗格尼医学中心在内的主要医学中心，NeuroRx正在对RLF-100进行II/III期临床试验。这项多中心临床试验招募了重症COVID-19患者，这些患者存在呼吸衰竭。这些研究的目的旨在通过RLF-100拯救II型肺泡细胞来降低患者死亡率。

 

原始出处：

https://www.firstwordpharma.com/node/1735200

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    2020-10-30 chendoc254

    #VIP#

    0

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    2020-07-03 125619a9m67暂无昵称

    学到了

    0

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    2020-06-27 Eleven14

    #快速通道资格#

    0

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    2020-06-27 12498cf9m40(暂无昵称)

    #呼吸窘迫#

    0

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    2020-06-25 医鸣惊人

    学习

    0

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