Baidu
map

ASCO 2022:低钠血症可能预示着更糟糕的结果,胃癌患者需警惕!

2022-06-02 MedSci原创 MedSci原创

值得关注

以往研究报道显示,低钠血症会增加实体瘤患者的死亡率和住院时间。然而,很少有低钠血症与胃癌相关的报道。来自美国圣何塞州立大学研究人员评估了低钠血症对胃癌患者的死亡率和发病率的影响。

在这项研究中,研究人员使用国际疾病分类 10 (ICD-10)调查了 2019 年全国住院患者样本,包括成年胃癌患者。使用多变量逻辑和线性回归分析调整混杂变量,包括性别、种族、Charlson合并症指数、慢性肾病、充血性心力衰竭、肝硬化、肾病综合征、甲状腺功能减退、肾上腺功能不全、酒精使用障碍、因血容量不足或精神性多尿症入院以及各种病人和医院特征。

近期,研究人员在ASCO大会上公布了研究结果,胃癌患者低钠血症的患病率为 13.59%,低钠血症导致院内死亡率增加。

具体而言,共有43015名胃癌患者,13.59%出现低钠血症。合并低钠血症胃癌患者的住院死亡率为 12.23%,而无低钠血症的胃癌患者为 6.69%。调整混杂因素后,低钠血症带来更高的死亡率。

另外,低钠血症还增加了住院时间、住院费用和进入ICU的几率,平均住院时间增加2.09天,平均住院费用总额增加22320美元。 此外,低钠血症患者出现急性肾衰竭的几率更高。两个研究组的脑水肿和精神状态改变发生率相等(P > 0.05)。

总之,胃癌患者发生低钠血症几率为13.59%,同时增加了死亡风险。那么,低钠血症的高效治疗是否有助于降低死亡率和改善预后仍有待未来研究确定。

原始出处

Jorge Franco, Diana Franco, Umer Farooq, Irene Ma.Does hyponatremia predict worse outcomes in gastric cancer?: A nationwide study.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1939399, encodeId=0ba3193939987, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Jun 20 11:49:43 CST 2022, time=2022-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769717, encodeId=b7ad1e69717b3, content=<a href='/topic/show?id=900b8323461' target=_blank style='color:#2F92EE;'>#胃癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83234, encryptionId=900b8323461, topicName=胃癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=377c38086944, createdName=huhuaidong400, createdTime=Fri Jan 13 16:49:43 CST 2023, time=2023-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361403, encodeId=9a83136140370, content=<a href='/topic/show?id=835426385a6' target=_blank style='color:#2F92EE;'>#低钠血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26385, encryptionId=835426385a6, topicName=低钠血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538292, encodeId=7f471538292b4, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=)]
    2022-06-20 quxin068
  2. [GetPortalCommentsPageByObjectIdResponse(id=1939399, encodeId=0ba3193939987, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Jun 20 11:49:43 CST 2022, time=2022-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769717, encodeId=b7ad1e69717b3, content=<a href='/topic/show?id=900b8323461' target=_blank style='color:#2F92EE;'>#胃癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83234, encryptionId=900b8323461, topicName=胃癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=377c38086944, createdName=huhuaidong400, createdTime=Fri Jan 13 16:49:43 CST 2023, time=2023-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361403, encodeId=9a83136140370, content=<a href='/topic/show?id=835426385a6' target=_blank style='color:#2F92EE;'>#低钠血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26385, encryptionId=835426385a6, topicName=低钠血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538292, encodeId=7f471538292b4, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1939399, encodeId=0ba3193939987, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Jun 20 11:49:43 CST 2022, time=2022-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769717, encodeId=b7ad1e69717b3, content=<a href='/topic/show?id=900b8323461' target=_blank style='color:#2F92EE;'>#胃癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83234, encryptionId=900b8323461, topicName=胃癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=377c38086944, createdName=huhuaidong400, createdTime=Fri Jan 13 16:49:43 CST 2023, time=2023-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361403, encodeId=9a83136140370, content=<a href='/topic/show?id=835426385a6' target=_blank style='color:#2F92EE;'>#低钠血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26385, encryptionId=835426385a6, topicName=低钠血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538292, encodeId=7f471538292b4, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1939399, encodeId=0ba3193939987, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Mon Jun 20 11:49:43 CST 2022, time=2022-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1769717, encodeId=b7ad1e69717b3, content=<a href='/topic/show?id=900b8323461' target=_blank style='color:#2F92EE;'>#胃癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83234, encryptionId=900b8323461, topicName=胃癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=377c38086944, createdName=huhuaidong400, createdTime=Fri Jan 13 16:49:43 CST 2023, time=2023-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361403, encodeId=9a83136140370, content=<a href='/topic/show?id=835426385a6' target=_blank style='color:#2F92EE;'>#低钠血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26385, encryptionId=835426385a6, topicName=低钠血症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c22f171, createdName=kord1982, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538292, encodeId=7f471538292b4, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Sat Jun 04 05:49:43 CST 2022, time=2022-06-04, status=1, ipAttribution=)]
    2022-06-04 zz12341238

相关资讯

爱大蒜的理由找到了!BMJ:22年国人研究显示,长年吃大蒜,胃癌死亡风险降低34%

BMJ:持续7年摄入大蒜补剂与胃癌死亡风险降低有关,与幽门螺杆菌治疗两周、摄入维生素补充剂7年有着相似的效果,但与胃癌发病率降低无关。

幽门螺杆菌研究获重大突破!这种美容因子竟是致癌帮凶

今年的5月29日是第18个“世界肠道健康日”,自2005年来世界胃肠病学组织(WGO)将每年的5月29日定为世界肠道健康日,旨在提醒人们注意肠道发出的警示,注意身体健康。

患者明明是颈胸背部疼痛,为何却戴上了一枚凶险的“戒指”?

贫血貌,全身皮肤黏膜无黄染,未见散在瘀点、瘀斑,周身浅表淋巴结未触及肿大,双肺叩诊呈浊音,两肺底呼吸音低,心律齐,心音有力,各瓣膜听诊区未闻及杂音。

ASCO 2022:经历过胃癌手术的患者,代谢综合征和脂肪肝患病风险较低

在消化道恶性肿瘤中,胃癌发病率位居前列,然而,胃癌患者的代谢综合征和脂肪肝发病风险尚不清楚。

J Gastroenterol:胃癌筛查计划对胃癌患者的长期预后的影响

采用上消化道内窥镜检查或在确诊前两年内进行胃癌筛查的患者的预后最好

胃癌常用免疫组化指标解读,看这一篇就够了!

“对症下药”才能“药到病除”。

Baidu
map
Baidu
map
Baidu
map