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JCO:吸烟让结直肠癌幸存患者更接近死神

2015-02-05 佚名 生物谷

近日,刊登在国际杂志Journal of Clinical Oncology上的一篇研究论文中,来自国外的研究人员通过研究表明,相比不吸烟的结直肠癌幸存者而言,吸烟的患者死亡的风险是前者的2倍,这就揭示了吸烟和结直肠癌患者死亡直接相关,该研究为后期开发有效的干预措施来预防结直肠癌患者的死亡风险提供了一定的帮助。 文章中研究者对美国癌症协会癌症预防研究II期阶段中从18.4万成年人中诊断出

近日,刊登在国际杂志Journal of Clinical Oncology上的一篇研究论文中,来自国外的研究人员通过研究表明,相比不吸烟的结直肠癌幸存者而言,吸烟的患者死亡的风险是前者的2倍,这就揭示了吸烟和结直肠癌患者死亡直接相关,该研究为后期开发有效的干预措施来预防结直肠癌患者的死亡风险提供了一定的帮助。

文章中研究者对美国癌症协会癌症预防研究II期阶段中从18.4万成年人中诊断出的2548名新发侵入性非转移性的结直肠癌患者进行调查分析,这些患者均为癌症幸存者,在随后的跟踪调查过程中有1074名个体存活平均7.5年,其中有453名患者因结直肠癌死亡。

研究者Peter Campbell博士表示,我们研究发现,诊断前吸烟者因各种原因而死亡的风险同患结直肠癌死亡的风险一样,都超过2倍,诊断前吸烟往往和较高的全因死亡率相关,但和结直肠癌相关的死亡率并无关系。诊断后吸烟往往会增加癌症患者至少2倍的死亡风险,而且和两倍的结直肠癌特异性死亡率直接相关。

对于吸烟者而言其机体往往更易出现恶性肿瘤,而吸烟同时也会降低结直肠患者疗法的效果,研究者最后说道,未来研究我们还将继续深入理解为何吸烟会增加结直肠癌特异性的死亡率,并且确定是否确诊癌症后戒烟可以有效降低结直肠癌患者的死亡率。


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  1. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-08-29 lidong40
  2. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-24 xjtumed10

    学习了,学习了!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-23 orthoW

    不错的文章,学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-16 Johnny1989

    0

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    2015-02-16 Johnny1989

    已阅

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-16 windmilL1989

    已阅

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-16 jianlion

    还是不吸烟好

    0

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  9. [GetPortalCommentsPageByObjectIdResponse(id=1891172, encodeId=981318911e225, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Sat Aug 29 22:22:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16883, encodeId=50681688391, content=学习了,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25f71612570, createdName=xjtumed10, createdTime=Tue Feb 24 11:24:00 CST 2015, time=2015-02-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16769, encodeId=d55e16e6997, content=不错的文章,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f2fb1607679, createdName=orthoW, createdTime=Mon Feb 23 11:41:00 CST 2015, time=2015-02-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16067, encodeId=0d621606e18, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=167, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16068, encodeId=febd16068a4, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:35:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15905, encodeId=938a159054c, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:41:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15582, encodeId=a24115582b2, content=还是不吸烟好, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Mon Feb 16 08:11:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452741, encodeId=82941452e4164, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Sat Feb 07 04:22:00 CST 2015, time=2015-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15088, encodeId=356e1508856, content=吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Feb 05 14:04:00 CST 2015, time=2015-02-05, status=1, ipAttribution=)]
    2015-02-05 lovetcm

    吸烟对会儿街采等都有关注你一下但是需要区分一下到底是早期中期和晚期以及它的影响程度

    0

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ASCO GI 2015 :高维生素D水平可改善进展期结直肠癌患者生存

一项关于新诊断转移性结直肠癌">结直肠癌患者的Ⅲ期研究的前瞻性数据分析显示,化疗和靶向治疗后维生素D水平较高的患者其结局更好,维生素D水平最高和最低的患者中位总生存期分别为32.6个月和24.5个月。 主要研究作者、达纳-法伯癌症中心、哈佛医学院Kimmie Ng助理教授:我们的研究显示高维生素D水平与显著改善生存有关,最终目标是希望通过这一结果指导补充维生素D治疗结直肠癌的随机研究,从而

JAMA Surg:原发肿瘤切除术或不能提高Ⅳ期结直肠癌生存率

一项美国回顾性研究显示,1988年~2010年间,大多数Ⅳ期结直肠癌(CRC)患者曾接受过原发肿瘤切除手术,而自2001年起,原发肿瘤切除手术的临床使用逐渐减少,但患者生存率较前改善。随着化疗药物及生物制剂的不断问世,CRC原发肿瘤切除手术或已不再是常规治疗方式。论文1月14日在线发表于《美国医学会杂志·外科学》(JAMA Surg)。 研究纳入美国国立癌症研究所CRC监测、流

JCO:结直肠癌患者FOLFIRI+爱必妥的应用以及RAS突变状态的研究

目的:CRYSTAL是一项III期临床试验,它表明了在KRAS外显子2(密码子12、13)野生型的转移性结直肠癌(mCRC)患者的一线治疗中,FOLFIRI(氟脲嘧啶+亚叶酸钙+伊立替康)方案加上西妥昔单抗能显著提高患者的OS、PFS和客观缓解率。通过更多的RAS基因检测对本试验进行亚组再分析。 材料和方法:将CRYSTAL研究中KRAS外显子2野生型患者的组织样本重新进行其它RAS基因检测。包

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