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DDS:经口内镜下肌切开术治疗失弛缓症患者的长期疗效分析

2019-04-21 不详 MedSci原创

经口腔内镜下肌切开术在治疗贲门失弛缓症中有很大的作用,因此,本研究旨在评估经口腔内镜下肌切开术(POEM)对贲门失弛缓症患者的远期疗效。

背景及目的
经口腔内镜下肌切开术在治疗贲门失弛缓症中有很大的作用,因此,本研究旨在评估经口腔内镜下肌切开术(POEM)对贲门失弛缓症患者的远期疗效。

方法
研究人员回顾性分析了在浙江中医药大学第一附属医院接受POEM治疗的115例患者(中位年龄45岁)和中位随访36个月的前瞻性资料。主要观察结果为Eckardt评分和食道下端括约肌压力变化,并观察食管反流情况。

结果
研究结果显示所有患者的平均Eckardt评分从术前的7.5±1.9降至术后1个月的2.3±1.4(P<0.001)。治疗成功率为91.3%[95%CI:86.2-96.4]。所有患者中共发生16起(13.9%)手术失败,4例无反应者,8例早期复发(3个月至3年),4例晚期复发(3年后)。此外,21名(20.6%)患者在两年的随访期间出现反流症状。在随后的三年随访期间,仅新增了一名有症状反流的患者。此外,71例(61.7%)患者在POEM后接受镜检查,13例(18.3%)患者被诊断为反流性食管炎。

结论
POEM治疗贲门失弛缓症安全有效,具有良好的远期疗效。

原始出处:

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    2019-04-21 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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