Baidu
map

Am J Gastroenterol:IBD患者,需注意维生素D水平

2016-03-23 MedSci MedSci原创

研究者进行了一项研究,探究维生素D水平和炎症性肠病(IBD)的关系。研究者对IBD患者进行了长达5年的随访,根据患者的维生素D水平将其分类。通过使用药物类型、医疗利用率、炎症相关生化标志物(CRP和ESR)、疼痛、临床疾病活动评分和健康相关生活质量评估患者IBD的临床状况。研究数据显示,纳入的965名IBD患者中,克罗恩病占61.9%,溃疡性结肠炎占38.1%,患者平均年龄44岁,其中女性占52.

研究者进行了一项研究,探究维生素D水平和炎症性肠病(IBD)的关系。

研究者对IBD患者进行了长达5年的随访,根据患者的维生素D水平将其分类。通过使用药物类型、医疗利用率、炎症相关生化标志物(CRP和ESR)、疼痛、临床疾病活动评分和健康相关生活质量评估患者IBD的临床状况。

研究数据显示,纳入的965名IBD患者中,克罗恩病占61.9%,溃疡性结肠炎占38.1%,患者平均年龄44岁,其中女性占52.3%。所有患者中,29.9%的患者维生素D水平低。5年的随访时间里,与维生素D水平正常的患者相比,低水平的维生素D组需要更多的类固醇激素、生物制剂、麻醉、CT扫描、急救科就诊、住院和手术 (P<0.05)。

不仅如此,低水平维生素D组患者的疼痛、临床疾病活动评分和健康相关生活质量更糟糕(P<0.05)。使用维生素D补充剂的患者可显著减少他们的医疗利用率。

研究结果表明,IBD患者中常见低水平的维生素D,而该种维生素的缺乏又于发病率和严重程度相关,因此其潜在影响,临床上要对维生素D进行监测并治疗。

原始出处:


Kabbani TA,Koutroubakis IE,Schoen RE,et al.Association of Vitamin D Level With Clinical Status in Inflammatory Bowel Disease: A 5-Year Longitudinal Study.Am J Gastroenterol 2016 Mar 8;


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2071624, encodeId=0bde20e1624c2, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Feb 08 14:26:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063960, encodeId=1f4c2063960d0, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue May 17 21:26:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710854, encodeId=aceb1e108548f, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Jan 18 22:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263420, encodeId=962f126342077, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Fri Mar 25 12:26:00 CST 2016, time=2016-03-25, status=1, ipAttribution=)]
    2017-02-08 许安
  2. [GetPortalCommentsPageByObjectIdResponse(id=2071624, encodeId=0bde20e1624c2, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Feb 08 14:26:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063960, encodeId=1f4c2063960d0, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue May 17 21:26:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710854, encodeId=aceb1e108548f, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Jan 18 22:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263420, encodeId=962f126342077, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Fri Mar 25 12:26:00 CST 2016, time=2016-03-25, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2071624, encodeId=0bde20e1624c2, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Feb 08 14:26:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063960, encodeId=1f4c2063960d0, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue May 17 21:26:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710854, encodeId=aceb1e108548f, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Jan 18 22:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263420, encodeId=962f126342077, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Fri Mar 25 12:26:00 CST 2016, time=2016-03-25, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2071624, encodeId=0bde20e1624c2, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed Feb 08 14:26:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063960, encodeId=1f4c2063960d0, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Tue May 17 21:26:00 CST 2016, time=2016-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1710854, encodeId=aceb1e108548f, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Wed Jan 18 22:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1263420, encodeId=962f126342077, content=<a href='/topic/show?id=75bc930217' target=_blank style='color:#2F92EE;'>#IBD#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9302, encryptionId=75bc930217, topicName=IBD)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Fri Mar 25 12:26:00 CST 2016, time=2016-03-25, status=1, ipAttribution=)]
    2016-03-25 bnurmamat

相关资讯

Thyroid:维生素D与乳头状甲状腺癌的进展和预后

维生素D与多种癌症的进展和预后有关,研究者进行了一项研究,探究维生素D是否会对乳头状甲状腺癌(PTC)的进展和预后产生影响。该研究共纳入820名PTC患者,术前通过血液检测25 -羟维生素D水平。通过患者临床、病理和复发数据评估维生素D对预后的影响。根据术前维生素D水平将患者分为四组。研究数据显示,795 (97%)名患者表现出维生素D缺乏 (<30 ng/mL)。维生素D的水平与年龄、BM

Lancet Diabetes Endo:孕妇补充维生素D并不增加后代骨质含量

背景有研究表明,孕妇维生素D状况与后代骨量有关,但不是所有的观察性研究都可得出这样的结论。 然而,在一项随机对照试验中,研究人员发现,孕妇在孕期补充充足的维生素D并不能增加后代骨量。该研究旨在评估孕期补充维生素D相比未补充维生素D的孕妇而言生育的孩子全身骨矿物质含量(BMC)更高。 方式母体维生素D骨质疏松研究(MAVIDOS)是一个多中心、双盲、随机、安慰剂对照实验,研究人员从英国三个研究地点(

Clinical Oncology:前列腺癌患者维生素D水平普遍较低

埃文斯顿西北大学的研究人员将研究结果发表在Clinical Oncology。 这一发现对同意保守治疗的前列腺癌患者十分有利。泌尿外科副教授Adam Murphy指出,黑皮肤且维生素D摄入量低或日照量少的男性在诊断PSA升高或前列腺癌时应评估其机体维生素D水平是否正常。如果维生素D缺乏,则应补充。 研究人员发现低维生素D和恶性前列腺癌之间有某种联系,但是这些研究都是基于治疗前的血液采样得出的结论。

AJPH:母乳喂养的宝宝整个哺乳期都要添加维生素D

母乳喂养中不添加维生素D,会宝宝导致维生素D缺乏风险的增加,尤其是母乳喂养超过一年的宝宝。研究成果发表在American Journal of Public Health。多伦多圣迈克尔医院儿科的Jonathon Maguire博士说:“哺乳超过一年后的时间越长,维生素D水平越低。添加维生素D可预防的宝宝,即使哺乳时间超过1年,也不会出现维生素D缺乏。研究发现提示,应该在整个哺乳期都添加维生素D。

SLEEP:OSAS患者的血清维生素D水平与病情明显相关

目标研究的目的在于评估阻塞性睡眠呼吸暂停综合症(OSAS)患者的25(OH)D水平及与OSAS严重程度、嗜睡、肺功能、夜间活动后心率和身体构成之间的关系。同时也比较相比同时患有OSAS和维生素D缺乏(VDD)的患者而言,OSAS患者体内25(OH)D的水平。 方法 这项研究在一家市中心临床睡眠医学门诊中心进行,是一项横断面研究。我们招募了近期进行夜间多导睡眠图并新确立诊断的白种人,比较他们和未患有

Diabetes Obes Metab:补充维生素D可避免早发型胰岛素抵抗

近期发表在Diabetes, Obesity and Metabolism杂志的研究称,对维生素D不足的患者早期使用维生素D进行干预,可以避免早发型胰岛素抵抗。来自色列贝尔谢巴本班古里昂大学的Sigal Tepper博士和同事对130名没有糖尿病的男性进行了一项研究,参与者平均年龄47.25岁,血清25(OH)D<20 ng/mL。将参与者分为补充维生素D治疗组(维生素D 100,000 I

Baidu
map
Baidu
map
Baidu
map