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Fertil Steril:受孕前产妇摄入哪种饮料对生殖成功的威胁更大?

2017-12-29 吴星 环球医学

2017年12月,发表在《Fertil Steril》的一项由以色列和美国科学家进行的前瞻性研究,考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性。

2017年12月,发表在《Fertil Steril》的一项由以色列和美国科学家进行的前瞻性研究,考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性。

目的:旨在研究产妇摄入的饮料类型是否影响IVF结局。

设计:前瞻性研究。

地点:大学附属三级医疗中心。

患者:2014年~2016年340例正在进行IVF治疗不育症和进行常染色体隐性遗传病的前遗传学诊断的女性在卵巢刺激期间入组,并完成了描述她们常规饮料摄入的调查问卷。

干预:无。

主要结局考察:从病历记录中获取IVF结局。通过具体饮料的咖啡因总含量乘以摄入咖啡的频率计算总的咖啡因摄入。具体类型的饮料和IVF结局之间的相关性使用泊松和逻辑回归模型进行分析,并调整了可能的混杂因素。

结果:较高摄入含糖汽水与卵巢刺激后较少的总的、成熟的和受精的卵母细胞以及高质量胚胎相关。与不摄入含糖汽水的女性相比,摄入含糖汽水的女性平均获卵数少1.1,成熟卵母细胞获得数少1.2,受精卵母细胞数少0.6,优质胚胎数少0.6。此外,与不饮用含糖汽水的女性相比,每天消耗0.1~1杯和>1杯含糖汽水的女性,造成活产的治疗周期百分比的调整后差异分别为-12%和-16%。咖啡、咖啡因或饮用无糖汽水与IVF结局之间无相关性。

结论:独立于其咖啡因含量,含糖汽水比咖啡因和不加糖的含咖啡因饮料相比是生殖成功的更大威胁。

原始出处:

Machtinger R,et al. Association between preconception maternal beverage intake and in vitro fertilization outcomes. Fertil Steril. 2017 Dec;108(6):1026-1033. doi: 10.1016/j.fertnstert.2017.09.007. Epub 2017 Oct 3.

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content=2017年12月.发表在<FertilSteril>的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 29 17:03:14 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2018-06-26 szhvet
  2. 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    2018-02-21 楚秀娟
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content=2017年12月.发表在<FertilSteril>的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 29 17:03:14 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2018-01-02 略略略~

    也就是说备孕不能喝含糖汽水

    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/10/16d33b9abecd6440b30b37e6ad8db1a6.jpg, createdBy=f6f72168266, createdName=阿杜12138, createdTime=Fri Dec 29 18:57:05 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273592, encodeId=8da92e35922e, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Fri Dec 29 18:37:04 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273548, encodeId=8e6e2e3548c5, 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    2017-12-30 sunfeifeiyang

    学习

    0

  5. 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    2017-12-30 神功盖世

    学习

    0

  6. 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    2017-12-29 131****1460

    学习了受益匪浅

    0

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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/10/16d33b9abecd6440b30b37e6ad8db1a6.jpg, createdBy=f6f72168266, createdName=阿杜12138, createdTime=Fri Dec 29 18:57:05 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273592, encodeId=8da92e35922e, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Fri Dec 29 18:37:04 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273548, encodeId=8e6e2e3548c5, content=2017年12月.发表在<FertilSteril>的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 29 17:03:14 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-29 wxl882001

    了解一下

    0

  8. 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createdBy=795f27597722, createdName=楚秀娟, createdTime=Wed Feb 21 23:33:00 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274733, encodeId=721f2e4733ee, content=也就是说备孕不能喝含糖汽水, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/331C593BCC29B3FF699E8F5F4A6EC4F2/100, createdBy=77e92234930, createdName=略略略~, createdTime=Tue Jan 02 13:28:12 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273838, encodeId=01792e383882, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/10/16d33b9abecd6440b30b37e6ad8db1a6.jpg, createdBy=f6f72168266, createdName=阿杜12138, createdTime=Fri Dec 29 18:57:05 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273592, encodeId=8da92e35922e, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Fri Dec 29 18:37:04 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273548, encodeId=8e6e2e3548c5, content=2017年12月.发表在<FertilSteril>的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 29 17:03:14 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-29 阿杜12138

    含糖汽水

    0

  9. 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content=2017年12月.发表在<FertilSteril>的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Dec 29 17:03:14 CST 2017, time=2017-12-29, status=1, ipAttribution=)]
    2017-12-29 戒馋,懒,贪

    谢谢分享学习了

    0

  10. 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    2017-12-29 有备才能无患

    2017年12月.发表在的一项由以色列和美国科学家进行的前瞻性研究.考察了受孕前产妇摄入饮料类型和体外受精(IVF)结局之间的相关性

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