ARTMS和Isotopia Molecular Imaging宣布成功通过QUANTM Irradiation System™和固态靶材，用经由回旋加速器生产的68Ga对PSMA-11进行多居里标记

2021-01-21 国际文传国际文传

ARTMS和Isotopia Molecular Imaging宣布成功通过QUANTM Irradiation System™和固态靶材

ARTMS Inc. (ARTMS)和Isotopia Molecular Imaging (Isotopia)欣然宣布，成功通过ARTMS拥有专利的Quantum Irradiation System™ (QIS™)固态靶材系统，用超过2居里(Ci)的经由回旋加速器生产的镓68 (⁶⁸Ga)对Isotopia的前列腺癌成像试剂盒产品PSMA-11进行了放射性标记。

该款前列腺特异性膜抗原(PSMA)试剂盒专门设计用于制备⁶⁸Ga-PSMA-11（一种靶向标记PSMA的放射性药物，用于正电子发射断层扫描(PET)对前列腺癌的成像），经过不到2个小时的辐照，获得了高活性的经由回旋加速器生产的⁶⁸Ga的放射性标记。通过使用QIS™和ARTMS的高性能⁶⁸Zn固态靶材进行多轮成功的⁶⁸Ga生产之后，该款Isotopia试剂盒获得500毫居里(mCi)至刚超过2900 mCi的⁶⁸Ga放射性标记。所得产品显示有6小时的稳定性和放射化学纯度，达到或超过所有法规标准。回旋加速器生产的⁶⁸Ga与试剂盒解决方案相结合，将使放射药房近乎无限次获得该诊断产品以及具有成本效益的解决方案。

ARTMS首席执行官Charles S. Conroy表示：“对⁶⁸Ga放射性标记产品的需求将很快超过来自⁶⁸Ge/⁶⁸Ga发生器的供应量。ARTMS的QUANTM Irradiation System™ (QIS™)可提供分子成像界妥善地服务患者所需的高活性和高品质的⁶⁸Ga。QIS™的每小时多居里⁶⁸Ga产量是我在核医学职业生涯中见过的少数真正的颠覆者之一。我们很高兴与合作伙伴一起向临床工作者和患者提供按需⁶⁸Ga剂量。”

Isotopia Molecular Imaging首席执行官Eli Shalom博士表示：“Isotopia专注于开发完美服务我们的患者的诊断和治疗工具。我们认为⁶⁸Ga是与Lu177治疗手段进行配合的更好的诊断工具。Isotopia的高活性PSMA“试剂盒”是全球影像界在如何诊断前列腺癌方面的一次重大进步。多剂量药瓶的制备将使药房能够提供单位剂量，并使临床工作者可以对患者进行很少限制至无限制的成像。此外，5分钟的制备和95%以上的放射化学纯度将提高效率，并节省放射药房的时间和金钱。我们的目标是不断上市面向50和100mCi发生器、经由回旋加速器生产的⁶⁸Ga和Lu177标记的基于试剂盒的解决方案。”

ARTMS最近宣布，加拿大卫生部已核准其回旋加速器生产的^99mTc产品。ARTMS将不断开发包括⁶⁸Ga在内的基于回旋加速器的产品，重点是优化生产潜能并满足监管部门对使用放射性药物试剂盒的要求。

关于前列腺癌
前列腺癌是全球第四大常见癌症，2018年，初诊为前列腺癌的男士有130万。尽管治疗取得进步，但前列腺癌仍造成大量死亡，2018年有超过365,000名男士死于该病。诊断率正在增加，前列腺癌最高发地区有美国、欧洲、澳大利亚和新西兰。

关于ARTMS
ARTMS Inc.总部位于加拿大不列颠哥伦比亚省温哥华，公司开发的新颖技术和产品实现了世界上最常用的诊断成像同位素高品质的大量生产，是该领域的全球领导者。ARTMS的旗舰产品QUANTM Irradiation System^TM (QIS^TM)采用药物分配器和院内医用回旋加速器，可实现重要的医用同位素，例如镓68 (⁶⁸Ga)、锆89 (⁸⁹Zr)、锝99m (^99mTc)和铜64 (⁶⁴Cu)的分散、具有成本效益、大规模的生产，使用户能够控制其供应链。ARTMS在全球将这些屡获殊荣的加拿大专利发明商业化，有望彻底改变核医学行业的前景。

关于Isotopia
Isotopia Molecular Imaging Ltd是Metrontario集团与以色列放射性药物领域部分领先科学家之间的合作。Isotopia开发团队是一支多学科团队，包括核药剂师、放射化学家、核工程师和物理学家。经验丰富的Isotopia团队，加上放射性核素药房、回旋加速器设施、¹⁷⁷Lu生产单位和无菌制造，组成一个成熟的开发平台。Isotopia在科学界和医学界之间建立了合作关系，以进一步开发和试验用于成像应用和分子治疗的新标记。

原文阅读：http://www.businesswirechina.com/zh/news/45548.html

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2021-07-21 360611850

#TMS#

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2021-06-08 gongliu

#system#

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2021-03-25 ms9608593228839890

#DIA#

74 0
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2021-08-07 ms6829001416292975

#NTM#

76 0
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createdAvatar=, createdBy=d1067833268, createdName=12498bb3m92(暂无昵称), createdTime=Sat Jan 23 07:36:05 CST 2021, time=2021-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1517841, encodeId=ab21151e841ea, content=<a href='/topic/show?id=44156886664' target=_blank style='color:#2F92EE;'>#生产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68866, encryptionId=44156886664, topicName=生产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37a111112788, createdName=ms1343860338762272, createdTime=Sat Jan 23 07:36:05 CST 2021, time=2021-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=918830, encodeId=3d0b91883008, content=<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, 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2021-01-23 zhaojie88

#ART#

76 0
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2021-01-23 江川靖瑶

#SMA#

84 0
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2021-01-23 12498bb3m92(暂无昵称)

#STEM#

87 0
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2021-01-23 ms1343860338762272

#生产#

81 0
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2021-01-21 zb1235672

#学习#

113 0
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