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大气PM2.5小幅降低的降压效果与限盐类似!阜外医院郑昕等研究称

2020-03-02 循环 中国循环杂志

阜外医院郑昕等发表华中地区大样本的典型性人群横断面调查数据发现,PM2.5 长期暴露会导致血压升高,尤其是对收缩压的影响最大。该研究显示,PM2.5 每增高10 μg/m3,收缩压、舒张压、脉压和平均动脉压分别增加2.47 mmHg、0.69 mmHg、1.79 mmHg 和1.28 mmHg。虽然PM2.5 长期暴露浓度每增加10 μg/m3,个体水平上血压仅上升1~2 mmHg。但研究者认为,

阜外医院郑昕等发表华中地区大样本的典型性人群横断面调查数据发现,PM2.5 长期暴露会导致血压升高,尤其是对收缩压的影响最大。

该研究显示,PM2.5 每增高10 μg/m3,收缩压、舒张压、脉压和平均动脉压分别增加2.47 mmHg、0.69 mmHg、1.79 mmHg 和1.28 mmHg。

虽然PM2.5 长期暴露浓度每增加10 μg/m3,个体水平上血压仅上升1~2 mmHg。

但研究者认为,这一微小的改变在人群水平上具有重要的公共卫生意义—环境中每立方米空气中的PM2.5减少几微克,其对人群血压影响与采取减少钠盐摄入以及限制饮酒等高血压非药物干预措施的影响类似。

进一步分析结果显示老年人、男性、患高血压者PM2.5 长期暴露后收缩压升高更为显着。

研究共纳入华中地区(河南省,湖北省,湖南省)18 个城市的243 904 例调查对象,92 819 例(38.1%)为男性。

来源:宋佳丽,胡爽,唐桂刚,等. 我国华中地区大气PM2.5 长期暴露与成人血压水平的相关性分析. 中国循环杂志, 2019, 34: 568.

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    2020-03-02 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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