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ACOG实践指南:雌激素依赖性乳腺癌史的病人中阴道雌激素的使用

2016-02-24 MedSci MedSci原创

AOCG实践指南第659号:在有雌激素依赖性乳腺癌病史的女性中阴道雌激素的使用 摘要:癌症治疗应关注特殊女性人群的生存问题,包括癌症导致的高雌激素相关的副反应和癌症幸存者自然绝经后的不良反应。全身性和阴道雌激素广泛用于缓解血管舒缩,性交障碍,和一般人群下尿路感染等相关症状。然而,考虑到部分癌症是雌激素敏感的,对目前患有乳腺癌或曾有乳腺癌病史的女性使用激素疗法的安全性仍令人担忧。 建议和

AOCG实践指南第659号:在有雌激素依赖性乳腺癌病史的女性中阴道雌激素的使用

摘要:癌症治疗应关注特殊女性人群的生存问题,包括癌症导致的高雌激素相关的副反应和癌症幸存者自然绝经后的不良反应。全身性和阴道雌激素广泛用于缓解血管舒缩,性交障碍,和一般人群下尿路感染等相关症状。然而,考虑到部分癌症是雌激素敏感的,对目前患有乳腺癌或曾有乳腺癌病史的女性使用激素疗法的安全性仍令人担忧。

建议和总结:

正在经历乳腺癌和乳腺癌治疗后女性,控制泌尿生殖道症状和萎缩相关的尿路症状的一线治疗是非激素疗法。

雌激素依赖性乳腺癌病史的女性出现泌尿生殖道症状,非激素疗法无效时,可考虑使用阴道雌激素。

使用阴道雌激素应与患者的肿瘤医生协调决定。另外,应以知情同意为前提,在女性获知使用低剂量阴道雌激素的利弊后做出决定。

没有数据显示对正在接受乳腺癌治疗和有乳腺癌病史的女性中使用阴道雌激素缓解泌尿生殖道症状会增加肿瘤复发的风险。

当决定使用阴道雌激素时,应按照能缓解阴道症状的最小剂量和有限时间内使用。

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    2016-08-02 1dd8c52fm63(暂无匿称)

    了解一下!

    0

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    2016-02-25 仁心济世

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