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JAMA Oncology:韩国新研究确定乙肝发展为肝癌的很大风险因素

2018-03-27 Lily 来宝网

根据在网上发表的一份研究报告,对于慢性乙型肝炎病毒(HBV)患者,体重指数(BMI)与肝细胞癌(HCC)的风险显著相关,女性比男性更容易患肝癌。

【BMI与慢性乙型肝炎患者肝细胞癌风险的关系】根据在网上发表的一份研究报告,对于慢性乙型肝炎病毒(HBV)患者,体重指数(BMI)与肝细胞癌(HCC)的风险显着相关,女性比男性更容易患肝癌。

来自韩国首尔国立大学研究生院的研究人员们利用国家健康保险服务公司的数据来检验BMI与慢性HBV感染患者肝癌发生之间的关系。参与者在2002至12月31日期间接受了健康检查,并于2007至12月31日前接受了随访。其中214,167名男性和156,155名女性患有慢性HBV感染

研究人员发现,在八年的随访中,男性和女性分别有11241个HCCs和3368个HCCs。无论是男性还是女性,HCC的风险与BMI呈剂量反应正相关。重度肥胖男性和女性肝癌的危险比分别为1.22和1.46,而BMI介于18.5至22.9kg/m2之间。与男性相比,超重女性的关联程度更大。女性BMI与HCC的相关性也较高。

研究人员在报告中写道:“我们的发现对临床和公共健康都有影响,支持对患有慢性HBV感染的肥胖患者,尤其是女性患者采取干预策略和进行医疗护理。众所周知,乙肝是肝癌的最大风险因素之一,如果可以确定哪些患者具有更高的风险,那么一定可以采取更加准确的措施,防患于未然。”

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1674448, encodeId=027516e44484b, content=<a href='/topic/show?id=e8aa13359b1' target=_blank style='color:#2F92EE;'>#Oncology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13359, encryptionId=e8aa13359b1, topicName=Oncology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb7226973259, createdName=circumcision, createdTime=Tue Sep 25 22:45:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1865388, encodeId=deb3186538859, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sun Jul 22 17:45:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334837, encodeId=e607133483e82, content=<a href='/topic/show?id=d16910002215' target=_blank style='color:#2F92EE;'>#韩国#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100022, encryptionId=d16910002215, topicName=韩国)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Thu Mar 29 00:45:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300645, encodeId=789230064527, content=女性比慢性更容易患肝癌.和以前了解的不一样.一直认为慢性患病率更高.且与体重相关患有慢性HBV感染的肥胖患者.尤其是女性患者采取干预策略和进行医疗护理.众所周知.乙肝是肝癌的最大风险因素之一.如果可以确定哪些患者具有更高的风险.那么一定可以采取更加准确的措施.防患于未然.", beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Thu Mar 29 00:25:14 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1674448, encodeId=027516e44484b, content=<a href='/topic/show?id=e8aa13359b1' target=_blank style='color:#2F92EE;'>#Oncology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13359, encryptionId=e8aa13359b1, topicName=Oncology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb7226973259, createdName=circumcision, createdTime=Tue Sep 25 22:45:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1865388, encodeId=deb3186538859, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sun Jul 22 17:45:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334837, encodeId=e607133483e82, content=<a href='/topic/show?id=d16910002215' target=_blank style='color:#2F92EE;'>#韩国#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100022, encryptionId=d16910002215, topicName=韩国)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Thu Mar 29 00:45:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300645, encodeId=789230064527, content=女性比慢性更容易患肝癌.和以前了解的不一样.一直认为慢性患病率更高.且与体重相关患有慢性HBV感染的肥胖患者.尤其是女性患者采取干预策略和进行医疗护理.众所周知.乙肝是肝癌的最大风险因素之一.如果可以确定哪些患者具有更高的风险.那么一定可以采取更加准确的措施.防患于未然.", beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Thu Mar 29 00:25:14 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-07-22 minlingfeng
  3. [GetPortalCommentsPageByObjectIdResponse(id=1674448, encodeId=027516e44484b, content=<a href='/topic/show?id=e8aa13359b1' target=_blank style='color:#2F92EE;'>#Oncology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13359, encryptionId=e8aa13359b1, topicName=Oncology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb7226973259, createdName=circumcision, createdTime=Tue Sep 25 22:45:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1865388, encodeId=deb3186538859, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sun Jul 22 17:45:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334837, encodeId=e607133483e82, content=<a href='/topic/show?id=d16910002215' target=_blank style='color:#2F92EE;'>#韩国#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100022, encryptionId=d16910002215, topicName=韩国)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Thu Mar 29 00:45:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300645, encodeId=789230064527, content=女性比慢性更容易患肝癌.和以前了解的不一样.一直认为慢性患病率更高.且与体重相关患有慢性HBV感染的肥胖患者.尤其是女性患者采取干预策略和进行医疗护理.众所周知.乙肝是肝癌的最大风险因素之一.如果可以确定哪些患者具有更高的风险.那么一定可以采取更加准确的措施.防患于未然.", beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Thu Mar 29 00:25:14 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1674448, encodeId=027516e44484b, content=<a href='/topic/show?id=e8aa13359b1' target=_blank style='color:#2F92EE;'>#Oncology#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13359, encryptionId=e8aa13359b1, topicName=Oncology)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cb7226973259, createdName=circumcision, createdTime=Tue Sep 25 22:45:00 CST 2018, time=2018-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1865388, encodeId=deb3186538859, content=<a href='/topic/show?id=16ce133504e' target=_blank style='color:#2F92EE;'>#Oncol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13350, encryptionId=16ce133504e, topicName=Oncol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b63894, createdName=minlingfeng, createdTime=Sun Jul 22 17:45:00 CST 2018, time=2018-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334837, encodeId=e607133483e82, content=<a href='/topic/show?id=d16910002215' target=_blank style='color:#2F92EE;'>#韩国#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100022, encryptionId=d16910002215, topicName=韩国)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Thu Mar 29 00:45:00 CST 2018, time=2018-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300645, encodeId=789230064527, content=女性比慢性更容易患肝癌.和以前了解的不一样.一直认为慢性患病率更高.且与体重相关患有慢性HBV感染的肥胖患者.尤其是女性患者采取干预策略和进行医疗护理.众所周知.乙肝是肝癌的最大风险因素之一.如果可以确定哪些患者具有更高的风险.那么一定可以采取更加准确的措施.防患于未然.", beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ad01994393, createdName=溜溜梅不酸, createdTime=Thu Mar 29 00:25:14 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-29 溜溜梅不酸

    女性比慢性更容易患肝癌.和以前了解的不一样.一直认为慢性患病率更高.且与体重相关患有慢性HBV感染的肥胖患者.尤其是女性患者采取干预策略和进行医疗护理.众所周知.乙肝是肝癌的最大风险因素之一.如果可以确定哪些患者具有更高的风险.那么一定可以采取更加准确的措施.防患于未然."

    0

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