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Clinical Rehabilitation:针灸治疗可改善阿尔茨海默病的认知和身体功能

2022-05-06 xuyihan MedSci原创

临床上常表现为记忆功能障碍、认知功能缺失、语言功能下降等,严重影响人们的生活与健 康。AD 的发病机制尚不明确。阿尔兹海默病( Alzheimer' s disease,AD) 又称原发性老年痴呆。

阿尔茨海默病是一种退行性的神经系统疾病,其风险随着年龄的增长而增加。它是痴呆症和老年残疾的最常见原因。阿尔茨海默氏病可以从轻度认知障碍发展到最终的痴呆症。同时伴随认知能力的下降会影响日常活动和身体功能。考虑到人口老龄化,痴呆症是医疗系统面临的主要挑战,也是最重要的公共卫生问题。然而,治疗阿尔茨海默氏症的药物已被证明可以减缓认知能力的下降,但却不能使之成为一个可治愈的疾病。非药物干预是治疗阿尔茨海默病的重要选择,因为它可以减缓认知能力的下降。78%的痴呆症患者选择了针灸相关的治疗,改善了生活质量。针灸相关的治疗是在位于经络上的特定穴位上完成的,这些穴位属于古代中医的范畴。近年来,这些治疗方法在世界范围内得到了越来越多的关注,然而,不同的针灸相关治疗方法会产生不同的效果。本研究旨在确定这些不同的针灸相关疗法是否能改善认知功能、身体功能和生活质量。

为了完成本项荟萃分析,研究人员收集了截止到 2021 年 1 月的八个电子数据库中的相关文献资料,包括 Medline、PubMed、EBSCO、Embase、Cochrane、Airiti 图书馆、中国国家知识基础设施和中国期刊全文数据库。对针灸类型、认知功能、日常生活活动、肌肉力量和生活质量进行了系统评价和荟萃分析。

总共收集了有 4191名参与者的66项研究,总体偏倚风险分较为适中。针灸对认知功能和自理能力的治疗效果适中,无创疗法和有创疗法有显着差异(p < 0.001)。6、8、12、24周认知功能差异显着,后两周自理能力差异显着(p<0.001)。Meta回归分析显示,每周针灸治疗后患者认知功能提高0.05分(p= 0.002),自理能力改善0.02分(p= 0.04)。肌肉力量有显着改善(p= 0.0003)。

本项研究证实针灸相关治疗有效改善了认知功能,治疗持续至少 6 周,但自理能力要在治疗 12 周后才开始显现效果。也证实了肌肉力量的改善。针灸相关疗法,尤其是无创疗法,并发症少,安全性高,或许可以为患者和护理人员提供多样化的选择和临床护理指南以供参考。

原始出处:

Chuan-Ju Lin. Et al. Acupuncture-related treatments improve cognitive and physical functions in Alzheimer's disease: A systematic review and meta-analysis of randomized controlled trials.Clinical Rehabilitation.2022.

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    2022-05-16 ms3000000726046463

    请问哪里可以进行针灸治疗?国内有吗?

    1

    展开1条回复
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    2022-05-06 病毒猎手
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    2022-05-06 zll0628
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    2022-05-06 qjddjq

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