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Ophthalmic Res.:筛查早产儿视网膜病变:优化筛查方法!

2017-07-29 cuiguizhong MedSci原创

法国第戎大学医院眼科Pallot C近日在Ophthalmic Res.发表了他们的一项重要工作,研究影响从早产儿早产的时间的因素和早产儿视网膜病变(ROP)检测,以优化开始筛查的时间点。

法国第戎大学医院眼科Pallot C近日在Ophthalmic Res.发表了他们的一项重要工作,研究影响从早产儿早产的时间的因素和早产儿视网膜病变(ROP)检测,以优化开始筛查的时间点。

他们采用多中心回顾性研究的方法,研究了在2011年1月1日至2015年12月31日期间,孕龄早于32周龄之前出生的早产儿和体重小于1,500克的早产儿。他们使用广视野眼底摄影进行ROP筛查。对调查人群及其特征进行记录。

在研究时间范围内,总共有1,266例早产儿,他们对其中的795例进行研究。他们发现,有一百七十四例(21.6%)第一次检查发现早产儿视网膜病变(ROP)的月经后时间(PMA)为32.3±1.6周,出生后年龄为5.4±1.0周(PNA)。检测到早产儿视网膜病变的第一个临床迹象的时间是在PMA的34.0±1.9周和PNA的7.2±1.8周。在早产和早产儿视网膜病变(ROP)检测之间,通过多变量分析中发现,较早的胎龄,较长的机械通气时间和较低的出生体重与之有明显的相关性(分别为p <0.0001,p <0.0001,p = 0.0359)。

因此,他们认为,第一次早产儿视网膜病变(ROP)筛查应该进行个性化,以适应第一次筛查时首个早产儿视网膜病变迹象,避免不必要的检查而没有筛查出早产儿视网膜病变。

原文出处:

Pallot, C., et al., Screening for Retinopathy of Prematurity: Insight into Optimizing Screening. Ophthalmic Res, 2017.

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    2017-07-31 zutt
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level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Jul 30 08:47:25 CST 2017, time=2017-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227936, encodeId=ea0722e93615, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Sun Jul 30 07:37:36 CST 2017, time=2017-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227923, encodeId=f9e222e92332, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sun Jul 30 07:17:09 CST 2017, time=2017-07-30, status=1, ipAttribution=)]
    2017-07-30 thlabcde

    好东西学习了!

    0

  8. 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GetPortalCommentsPageByObjectIdResponse(id=227923, encodeId=f9e222e92332, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sun Jul 30 07:17:09 CST 2017, time=2017-07-30, status=1, ipAttribution=)]
    2017-07-30 明月清辉

    谢谢分享,学习了

    0

  9. 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level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun Jul 30 08:47:25 CST 2017, time=2017-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227936, encodeId=ea0722e93615, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJiaCBO9f33YY0a9cL4rhSH23PNEOVia2szWTbUl6IgFnukCuC2ptOD5mAC0Ax8qGt2pjwudkREHlmA/132, createdBy=d39e1630897, createdName=1dd8aa01m06(暂无匿称), createdTime=Sun Jul 30 07:37:36 CST 2017, time=2017-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227923, encodeId=f9e222e92332, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sun Jul 30 07:17:09 CST 2017, time=2017-07-30, status=1, ipAttribution=)]
    2017-07-30 1dd8aa01m06(暂无匿称)

    学习学习学习

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=227923, encodeId=f9e222e92332, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sun Jul 30 07:17:09 CST 2017, time=2017-07-30, status=1, ipAttribution=)]
    2017-07-30 半夏微凉

    学习了谢谢分享

    0

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SCI REP:晚发性循环衰竭和持续气道正压是早产儿视网膜病变治疗需要的有用预测因素:一个9年回顾性分析

我们确定了TR-ROP的有用预测因子。我们的研究结果表明,具有LCC病史和CPAP长期呼吸支持的早产儿具有发展TR-ROP的高风险。

Ophthalmology:早产儿视网膜病变(ROP)新的危险因素被确定

这项研究的目的之一是确定早产儿视网膜病变(ROP)的“新”统计独立危险因素。另一个目标是评估任何新的风险因素是否可以解释治疗要求苛刻的ROP发生率的增加。来自丹麦的研究人员进行了一项回顾性,注册为基础的队列研究。这项研究的参与者为1997年至2008年出生在丹麦的早产儿(n=6490)。研究样本和31个候选的危险因素在3个国家登记册进行确定。数据被链接到一个独特的民事登记号码。31个候选的危险因素

JAMA:预防使用氟康唑不减少早产儿念珠菌病发生或死亡

侵袭性念珠菌病是早产儿迟发性感染的重要原因,临床体征往往表现细微。尽管采取抗真菌治疗,但其在早产儿中后果严重。伴随着念珠菌感染,近70%出生体重小于1000g的婴儿发生严重的神经发育障碍或死亡。既往随机安慰剂对照试验已表明,氟康唑预防性治疗可减少新生儿重症监护室(NICUs)侵袭性念珠菌病的发病率,以及念珠菌病的高疾病负担(≥15%)。 目前指南推荐包括在新生儿重症监护室中,对侵袭性念珠菌发病率较

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