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Otol Neurotol:在具有可用听力保守治疗的前庭神经鞘瘤患者中的听力结果分析

2018-07-30 AlexYang MedSci原创

最近,有研究人员在选择初步观察的散发性前庭神经鞘瘤(VS)患者中,鉴定分析了发展为无可用听力的风险。研究是一个回顾性的案例系列研究,包括了2个高级护理中心。研究包括了那些在干预前或者跟踪调查终止前具有可用听力且经历了至少2次听力图测定和2次MRI的VS患者。研究共包括了466名患者(平均年龄为57岁,肿瘤平均直径为7.3mm),他们具有可用听力并且跟踪调查的平均时间为2.3年(IQR 1.0 -

最近,有研究人员在选择初步观察的散发性前庭神经鞘瘤(VS)患者中,鉴定分析了发展为无可用听力的风险。研究是一个回顾性的案例系列研究,包括了2个高级护理中心。研究包括了那些在干预前或者跟踪调查终止前具有可用听力且经历了至少2次听力图测定和2次MRI的VS患者。

研究共包括了466名患者(平均年龄为57岁,肿瘤平均直径为7.3mm),他们具有可用听力并且跟踪调查的平均时间为2.3年(IQR 1.0 - 4.0)。诊断后第1、3、5、7和10年时,保持可用听力的 Kaplan-Meier评估比例(95% CI;处在风险中的数目)分别为 94% (91-96; 357)、77% (73-82; 172)、 66% (60-73; 81)、56% (49-65; 31)和44% (33-59; 10)。诊断时在纯音均值中每一个10dB的增加均与发展为无可用听力风险可能性增加2倍相关(风险比2.07; p<0.001)。单词认知得分中每增加的10%均与发展为无可用听力可能性增加1.5倍相关。

最后,研究人员指出,在患有散状VS的患者中,良好的基线单词认知评分与低的纯音均值与可用听力的保持联合关联。这些数据对指导患者咨询和优化治疗是有益的。

原始出处:

Hunter JB, Dowling EM, Lohse CM et al. Hearing Outcomes in Conservatively Managed Vestibular Schwannoma Patients With Serviceable Hearing. Otol Neurotol. 20 Jul 2018.

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    2018-08-01 ysjykql
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    2018-07-31 牛顿爱吃苹果

    学习了

    0

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    2018-07-30 天地飞扬

    了解一下,谢谢分享!

    0

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