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Drugs Aging:老年人中西药合用的情况你了解吗?

2018-01-19 闫盈盈 环球医学

2017年12月,发表于《Drugs Aging》上的一项系统评价,考察了老年人同时使用处方药和草药(HMPs)的发生率、模式、潜在相互作用和因素。

2017年12月,发表于《Drugs Aging》上的一项系统评价,考察了老年人同时使用处方药和草药(HMPs)的发生率、模式、潜在相互作用和因素。

背景:草药的使用在老年人中常见,然而,对与处方药物同时使用的情况知之甚少,潜在相互作用也了解不多。

目的:本系统评价的目的是对老年人同时使用处方药和HMPS的文献进行评估,从而评估药物联合使用相关的发生率、模式、潜在相互作用和因素。

方法:对Medline、PsycINFO、Embase、CINAHL、AMED、Web of Science和Cochrane数据库进行了系统检索,检索日期截止到2017年5月,检索内容为报道了≥65岁的患者同时使用处方药和HMPs的研究。使用Joanna Briggs研究所清单评估研究质量。政策和实践信息的证据和协调中心(EPPI-中心)混合方法研究的三阶段方法用于综合数据。

结果:纳入了22项研究。HMPs定义或什么是HMPs的信息经常缺失。老年人同时使用的发生率存在广泛差异,范围从5.3%~88.3%。最常与HMPs联合使用的处方药物为降压药、β-受体阻滞剂、利尿剂、降脂药、抗凝药、止痛药、抗组胺药、抗糖尿病药、抗抑郁药和他汀。最常使用的HMPs为银杏叶、大蒜、人参、圣约翰草、紫锥菊、锯棕榈、月见草油和姜。银杏叶、大蒜、人参与阿司匹林或华法林联合使用造成的出血的潜在风险是最常报道的草药-药物相互作用。一些数据表明,女性、家庭收入较低、学历低于高中水平与这种联用相关。

结论:同时使用处方药物和HMPS在老年人中的发生率相当高,而且潜在的相互作用已经被报道过。了解老年人处方药的合并用药情况,将有助于卫生保健专业人员正确地识别和管理患者的风险。

原始出处:
Agbabiaka TB, Wider B, Watson LK, et al.Concurrent Use of Prescription Drugs and Herbal Medicinal Products in Older Adults: A Systematic Review.Drugs Aging. 2017 Dec;34(12):891-905. doi: 10.1007/s40266-017-0501-7.

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    2018-02-06 爆笑小医
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    2018-03-12 tsing_hit
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    2018-01-21 minzju5057
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    2018-01-19 1e0e5a1fm42(暂无匿称)

    henhao

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