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J Appl Oral Sci:牙周治疗可改善牙周炎和糖尿病患者的全身炎症状况

2020-09-27 MedSci原创 MedSci原创

目前关于牙周治疗对2型糖尿病(T2D)和牙周炎患者的血糖控制和全身炎症的影响尚无定论。本研究旨在评估洁治和根面平整(SRP)对2型糖尿病(T2D)患者的代谢控制和全身炎症的影响,研究结果已在线发表于J

目前关于牙周治疗对2型糖尿病(T2D)和牙周炎患者的血糖控制和全身炎症的影响尚无定论。本研究旨在评估洁治和根面平整(SRP)对2型糖尿病(T2D)患者的代谢控制和全身炎症的影响,研究结果已在线发表于J Appl Oral Sci。

使用MEDLINE数据库通过PubMed和Cochrane对照试验中央登记册进行文献检索,从其最古老的记录到2018年7月。只有随机临床试验(RCT)被认为是合格的,用于评估牙周治疗对T2D患者代谢控制标志物[糖化血红蛋白(HbA1C)]和全身炎症[C反应蛋白(CRP)]的影响。使用Cochrane协作组风险评估工具对研究的质量进行评估。使用随机效应模型对HbA1c和CRP进行了Meta分析。通过计算每项研究中各组间均值(DM)差异的加权平均值来估计总体干预效果的大小。使用Q统计法(x2和I²)评估异质性。显著性水平确定为p<0.05。

 

结果,研究人员纳入了9项RCT。分析发现,SRP能有效降低HbA1c[DM=0.56(0.36-0.75);p<0.01]和CRP[DM=1.89(1.70-2.08);p<0.01]。研究未发现异质性(I2=0%,p>0.05)。

综上所述,该研究结果表明,SRP对T2D患者的代谢控制和全身炎症的减轻有一定作用。

 

原始出处:

 

Mauricio BaezaAlicia Morales, et al., Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis. J Appl Oral Sci. 2020 Jan 10;28:e20190248. doi: 10.1590/1678-7757-2019-0248. 

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    2021-05-24 小几洁
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    2020-09-28 ms9000001531324985

    利好消息

    0

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    2020-09-27 misszhang

    谢谢MedSci提供最新的资讯

    0

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众所周知,糖尿病可导致多种的代谢异常。不仅有糖、蛋白质、脂肪代谢的紊乱, 还有钙代谢负平衡和骨代谢异常。糖尿病性骨质疏松症是糖尿病在骨骼系统出现的严重并发症。

Diabetes Care:酮症酸中毒对新发或既往诊断1型糖尿病患儿认知功能的影响

单次DKA发作与1型糖尿病诊断后记忆力轻度下降有关。在既往有糖尿病的儿童中可检测到IQ较大幅度的下降,这表明在慢性高血糖症儿童中,DKA的作用可能会加剧。

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