Baidu
map

心血管

订阅

MedSci主页 / 所有栏目 / 心血管

梅奥：非梗阻性肥厚性心肌病的自然史

2016-03-26 MedSci MedSci原创

梅奥非梗阻型肥厚性心肌病
关注

为了描述一个大型的非梗阻性肥厚性心肌病(NO-HCM)队列研究的生存率并识别人群死亡率增加的危险因素。进行了一项回顾性观察研究，

为了描述一个大型的非梗阻性肥厚性心肌病(NO-HCM)队列研究的生存率并识别人群死亡率增加的危险因素。进行了一项回顾性观察研究，病人识别自1975年1月1日-2006年12月30日梅奥诊所HCM数据库。有静止性或活动性左室流出道阻塞的病人被排除在外。比较亚组间的超声心动图、临床和基因数据，比较预期人口比例与生存率。

总共识别了706个NO-HCM病人。中位随访时间5年（平均7年），208人死亡。匹配美国白人的年龄和性别的死亡率后整体生存率无差异(P=.77)。死亡独立预测因子包括诊断年龄、“爆发”HCM、短暂性脑缺血发作或卒中；使用可置入心脏转复除颤器（ICD）与死亡率负相关。排除ICD病人后，匹配年龄和性别的生存率无差异(P=.39)；年龄，之前发生TIA/卒中，和爆发的HCM是死亡的预测因子。

在这个队列中，患有NO-HCM的病人生存率与匹配美国白人年龄和性别的死亡率后相似。尽管使用ICD与死亡负相关，在排除此类病人后，整体生存率无差异。爆发HCM与死亡风险独立相关，识别了亚组中能够从更加具有侵略性治疗中获益的病人。

原始出处：

Virginia B. Hebl, William R. Miranda,Kevin C. Ong,et al,The Natural History of Nonobstructive Hypertrophic Cardiomyopathy,mayo clinic pro,2016


版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1819440, encodeId=e762181944042, content=<a href='/topic/show?id=ecb69948913' target=_blank style='color:#2F92EE;'>#非梗阻性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99489, encryptionId=ecb69948913, topicName=非梗阻性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Dec 22 23:23:00 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997391, encodeId=bf88199e3917e, content=<a href='/topic/show?id=67ec86244b1' target=_blank style='color:#2F92EE;'>#自然史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86244, encryptionId=67ec86244b1, topicName=自然史)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Sun Sep 18 19:23:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74269, encodeId=43aae4269f4, content=抱歉，不太懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Mon Mar 28 22:35:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368254, encodeId=5cfd13682547f, content=<a href='/topic/show?id=8a5e6242257' target=_blank style='color:#2F92EE;'>#梅奥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62422, encryptionId=8a5e6242257, topicName=梅奥)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622232, encodeId=ca40162223217, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-12-22 mgqwxj

    #非梗阻性#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1819440, encodeId=e762181944042, content=<a href='/topic/show?id=ecb69948913' target=_blank style='color:#2F92EE;'>#非梗阻性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99489, encryptionId=ecb69948913, topicName=非梗阻性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Dec 22 23:23:00 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997391, encodeId=bf88199e3917e, content=<a href='/topic/show?id=67ec86244b1' target=_blank style='color:#2F92EE;'>#自然史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86244, encryptionId=67ec86244b1, topicName=自然史)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Sun Sep 18 19:23:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74269, encodeId=43aae4269f4, content=抱歉，不太懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Mon Mar 28 22:35:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368254, encodeId=5cfd13682547f, content=<a href='/topic/show?id=8a5e6242257' target=_blank style='color:#2F92EE;'>#梅奥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62422, encryptionId=8a5e6242257, topicName=梅奥)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622232, encodeId=ca40162223217, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-09-18 freve

    #自然史#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1819440, encodeId=e762181944042, content=<a href='/topic/show?id=ecb69948913' target=_blank style='color:#2F92EE;'>#非梗阻性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99489, encryptionId=ecb69948913, topicName=非梗阻性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Dec 22 23:23:00 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997391, encodeId=bf88199e3917e, content=<a href='/topic/show?id=67ec86244b1' target=_blank style='color:#2F92EE;'>#自然史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86244, encryptionId=67ec86244b1, topicName=自然史)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Sun Sep 18 19:23:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74269, encodeId=43aae4269f4, content=抱歉，不太懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Mon Mar 28 22:35:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368254, encodeId=5cfd13682547f, content=<a href='/topic/show?id=8a5e6242257' target=_blank style='color:#2F92EE;'>#梅奥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62422, encryptionId=8a5e6242257, topicName=梅奥)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622232, encodeId=ca40162223217, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-03-28 1de5aaa9m95(暂无匿称)

    抱歉，不太懂

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1819440, encodeId=e762181944042, content=<a href='/topic/show?id=ecb69948913' target=_blank style='color:#2F92EE;'>#非梗阻性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99489, encryptionId=ecb69948913, topicName=非梗阻性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Dec 22 23:23:00 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997391, encodeId=bf88199e3917e, content=<a href='/topic/show?id=67ec86244b1' target=_blank style='color:#2F92EE;'>#自然史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86244, encryptionId=67ec86244b1, topicName=自然史)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Sun Sep 18 19:23:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74269, encodeId=43aae4269f4, content=抱歉，不太懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Mon Mar 28 22:35:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368254, encodeId=5cfd13682547f, content=<a href='/topic/show?id=8a5e6242257' target=_blank style='color:#2F92EE;'>#梅奥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62422, encryptionId=8a5e6242257, topicName=梅奥)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622232, encodeId=ca40162223217, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-03-28 cmj8wellington

    #梅奥#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1819440, encodeId=e762181944042, content=<a href='/topic/show?id=ecb69948913' target=_blank style='color:#2F92EE;'>#非梗阻性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99489, encryptionId=ecb69948913, topicName=非梗阻性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=669d219, createdName=mgqwxj, createdTime=Thu Dec 22 23:23:00 CST 2016, time=2016-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997391, encodeId=bf88199e3917e, content=<a href='/topic/show?id=67ec86244b1' target=_blank style='color:#2F92EE;'>#自然史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86244, encryptionId=67ec86244b1, topicName=自然史)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ced3193, createdName=freve, createdTime=Sun Sep 18 19:23:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74269, encodeId=43aae4269f4, content=抱歉，不太懂, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3a411691127, createdName=1de5aaa9m95(暂无匿称), createdTime=Mon Mar 28 22:35:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368254, encodeId=5cfd13682547f, content=<a href='/topic/show?id=8a5e6242257' target=_blank style='color:#2F92EE;'>#梅奥#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62422, encryptionId=8a5e6242257, topicName=梅奥)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1622232, encodeId=ca40162223217, content=<a href='/topic/show?id=b9578094833' target=_blank style='color:#2F92EE;'>#肌病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80948, encryptionId=b9578094833, topicName=肌病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Mon Mar 28 12:23:00 CST 2016, time=2016-03-28, status=1, ipAttribution=)]
    2016-03-28 爆笑小医

    #肌病#

    0

相关资讯

JCEM：梅奥医学中心儿科内分泌手术经验总结

手术治疗儿童内分泌疾病非常少见。而且在这个领域，大多数外科医师经验有限。为此，来自美国梅约诊所的Anna Kundel教授及其团队总结了过去二十年期间由高手术量的内分泌外科医师在儿科患者进行手术的经验，发现儿科内分泌手术可以在高手术量的外科医师操作下安全地进行，而且其并发症发生率与成人内分泌手术相差无几。该些结果在线发表在2013年12月11日的The Journal of

Proceedings：梅奥诊所日前发布多发性骨髓瘤2013版诊疗指南

来自梅奥诊所癌症中心的研究人员近期发布了多发性骨髓瘤诊治指南。该指南针对尚未参加临床试验的新近诊断为多发性骨髓瘤（multiple myeloma，MM）的患者。该指南能帮助临床医生便于为患者提供初始治疗、干细胞移植以及维持治疗。该指南发表于近期的《梅奥医学进展》（Mayo Clinic Proceedings ）杂志中，并且附带了来自明尼苏达洲、佛罗里达州以及阿利桑那州的梅奥癌症中心血液学家的一

2013版多发性骨髓瘤诊疗指南(梅奥诊所)

     来自梅奥诊所癌症中心的研究人员近期发布了多发性骨髓瘤诊治指南。该指南针对尚未参加临床试验的新近诊断为多发性骨髓瘤（multiple myeloma，MM）的患者。该指南能帮助临床医生便于为患者提供初始治疗、干细胞移植以及维持治疗。该指南发表于近期的《梅奥医学进展》（Mayo Clinic Proceedings ）杂志中，并且附带了来自明

2014-2015年度美国医院排名—梅奥历经24年逆袭成功

《美国新闻与世界报道》公布2014至2015年全美最佳医院榜单。明尼苏达州罗切斯特的梅约诊所（Mayo Clinic），今年超越麻省总医院和约翰霍普金斯医院，名列榜首。波士顿的麻省总医院排名第二，巴尔的摩的约翰霍普金斯医院第三。能够跻身这一荣誉榜的医院，至少要有6个专科获得非常高的评分才有资格入围。在全美接近5000家医院中，今年上榜的只有17家医院。排名第四至第十七的依次是：克里夫兰诊所（Cle

梅奥真的来了，将启动中国附属医院计划

日前，美国梅奥医疗集团(简称“梅奥”)与麦迪舜医疗集团(简称“麦迪舜医疗”)在位于美国明尼苏达州罗切斯特市的梅奥总部签署医疗服务合作总体协议，正式启动了梅奥中国附属医院网络计划。 梅奥与麦迪舜团队紧密合作进入中国市场 梅奥诊所作为世界一流的非营利性综合医院在国际医疗界享有崇高的声誉，已经连续20年在《美国和世界新闻报道》的“最佳医院”名单上名列前茅，被誉为医学领域的“最高法院”

Baidu
map
Baidu
map
Baidu
map