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阜外医院9年经验:哪些患者手术后易发生胸腔积液?

2020-01-16 xujing 中国循环杂志

阜外医院晏馥霞等发表研究称,年龄小、无开窗、术后总蛋白低、机械通气时间延长、乳糜胸的患者在全腔静脉肺动脉连接术(TCPC)后易发生持续性胸腔积液。研究将持续性胸腔积液定义为胸腔积液持续超过14天。本组病例中,持续性胸腔积液发生率为27.4%。在全腔静脉肺动脉连接术手术中,开窗是为一种有效的手术方式,近年来应用率较高,本组病例中,开窗的应用率45.1%。研究发现,不开窗患者的持续性胸腔积液风险增加。

阜外医院晏馥霞等发表研究称,年龄小、无开窗、术后总蛋白低、机械通气时间延长、乳糜胸的患者在全腔静脉肺动脉连接术(TCPC)后易发生持续性胸腔积液。

研究将持续性胸腔积液定义为胸腔积液持续超过14天。本组病例中,持续性胸腔积液发生率为27.4%。

在全腔静脉肺动脉连接术手术中,开窗是为一种有效的手术方式,近年来应用率较高,本组病例中,开窗的应用率45.1%。研究发现,不开窗患者的持续性胸腔积液风险增加。

此外,在该研究中,较短的机械通气时间预示着较低的持续性胸腔积液风险。

研究者分析,是因为机械通气产生的胸腔内压和中心静脉压升高,可能导致淋巴引流和胸膜液再吸收减少,,机械通气时间延长的患者通常需要更多的液体摄入,这会加重胸腔积液。

研究发现,持续性胸腔积液患者住院天数增加18天,住院费用增加6.17万元。

研究者指出,严格选择患者、高危患者开窗、提高术后总蛋白水平、避免机械通气时间延长、积极处理乳糜胸等,有助于降低持续性胸腔积液的风险,缩短住院时间,减少住院费用。

研究者对2010-2019年接受全腔静脉肺动脉连接术的525例患者进行回顾性分析,住院死亡率为2.1%。

来源:Luo Q, Zhao W, Su Z, et al. Risk Factors for Prolonged Pleural Effusion Following Total Cavopulmonary Connection Surgery: 9 Years' Experience at Fuwai Hospital. Front Pediatr. 2019, 7: 456.

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    2020-01-16 txqjm

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