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JACC:大样本研究显示先心病外科术后远期死亡率仍居高不下

2018-05-26 MedSci MedSci原创

先天性心脏病外科手术治疗能明显提高复杂先心病的生存率,但其远期的预后效果尚未阐明。本研究纳入了美国儿童心脏病数据库中的35998名接受了首次先心病外科手术治疗且存活下来的年龄小于21岁的患者,经过平均18年时间的随访,有3191名患者出现了死亡,标准化死亡率(SMR)为8.3(95% [CI]: 8.0 - 8.7),15年的SMR从早期的12.7(1982-1992)下降至晚期的10(1998-

先天性心脏病外科手术治疗能明显提高复杂先心病的生存率,但其远期的预后效果尚未阐明。本研究纳入了美国儿童心脏病数据库中的35998名接受了首次先心病外科手术治疗且存活下来的年龄小于21岁的患者,经过平均18年时间的随访,有3191名患者出现了死亡,标准化死亡率(SMR)为8.3(95% [CI]: 8.0 - 8.7),15年的SMR从早期的12.7(1982-1992)下降至晚期的10(1998-2003),即使在非严重的先心病患者如动脉导管未闭和房间隔缺损,SMR依旧处于较高水平,而SMR降低最明显的疾病是大动脉转位(11.0 vs 3.8;p<0.05)、完全性房室通道(31.3 vs 15.3; p<0.05)和单心室(53.7vs 37.3;p<0.05)。研究结果显示,各种类型的先天性心脏病外科术后的远期死亡率均较高,对于某些复杂的先心病,患者的远期死亡率逐年下降,但仍处于较高水平。原始出处:Logan G et al.Trends in Long-Term Mortality After Congenital Heart Surgery.JACC.2018 May.本文系梅

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    2018-11-23 hbwxf
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    2018-08-29 zhzhxiang
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    2018-05-28 ssnine
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    2018-05-27 一天没事干

    很好的学习机会

    0

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    2018-05-26 131****1460

    学习了受益匪浅

    0

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    2018-05-26 清风拂面

    谢谢分享学习

    0

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