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Radiology:计算机辅助CT测量亚实性结节实性成分评估预后的价值

2018-04-19 shaosai MedSci原创

本研究旨在验证亚实性非小细胞肺癌患者术后情况与多螺旋CT图像3D容积软件中所测实性成分大小的关系,并将结果发表在Radiology上。

本研究旨在验证亚实性非小细胞肺癌患者术后情况与多螺旋CT图像3D容积软件中所测实性成分大小的关系,并将结果发表在Radiology上。

本研究共纳入了96例术前行多螺旋CT发现亚实性非小细胞肺癌的患者(男性47例,女性49例;平均年龄±标准差为66岁±8)。由两名放射科医生测量每个结节轴位相2D最大大小(2D MSSA)、在重建图像上3D实性成分大小(3D MSSMPR)和每个结节中CT值超高0HU的实性体积(3D SV 0HU)。利用Cox比例风险模型评价术后复发和临床病史、病理特点、2D MSSA、 3D MSSMPR、3D SV 0HU 。

结果为,对于预测术后复发,2D MSSA、 3D MSSMPR、3D SV 0HU 的曲线下面积分别为0.796 (95% CI: 0.692, 0.900)/0.776 (95%CI: 0.667, 0.886)、0.835 (95%CI: 0.749, 0.922) 。3D SV 0HU 预测肿瘤复发的最佳截断值为0.54 cm 3,敏感性、特异性分别为0.933 (95% CI: 0.679, 0.998)、0.716 (95% CI: 0.605, 0.811)。无病生存期的预测因子权重3D SV 0HU 要不低于0.54 cm 3 (HR为6.61; P = .001) ,其次为淋巴结或血管受侵犯(HR, 2.96; P = .040)。

本研究表明,测量3D SV 0HU能够预测亚实性肺癌术后情况要比2D MSSA、3D MSSMPR更为准确。

原始出处:

Kamiya S, Iwano S, Umakoshi H. et al.Computer-aided Volumetry of Part-Solid Lung Cancers by Using CT: Solid Component Size Predicts Prognosis.Radiology.DOI: 10.1148/radiol.2018172319

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1716393, encodeId=64401e1639372, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Wed Mar 06 23:19:00 CST 2019, time=2019-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319668, encodeId=fdd1319668c5, content=不错的思路-学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d2f82367669, createdName=衣觉, createdTime=Tue May 29 12:35:35 CST 2018, time=2018-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307908, encodeId=fb9a30e90875, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Apr 21 11:54:25 CST 2018, time=2018-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307434, encodeId=dde630e4344c, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Fri Apr 20 05:19:34 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307433, encodeId=572630e4339c, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Fri Apr 20 05:18:41 CST 2018, time=2018-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307214, encodeId=2d8e30e214ba, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Apr 19 08:03:09 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307151, encodeId=14b630e1513f, content=非常好.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/21/9461f3b3c9f14e1d844256cdd08f2cf3.jpg, createdBy=a30f1426910, createdName=swfzhanggui, createdTime=Thu Apr 19 06:36:21 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307138, encodeId=12aa30e13876, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Thu Apr 19 06:27:36 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307131, encodeId=6db930e13172, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Apr 19 06:23:10 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=307119, encodeId=de2330e119cc, content=学习学习再学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Apr 19 05:44:35 CST 2018, time=2018-04-19, status=1, ipAttribution=)]
    2018-05-29 衣觉

    不错的思路-学习

    0

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    2018-04-21 秀红

    学习了

    0

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    2018-04-20 121832a9m88暂无昵称

    学习了

    0

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    2018-04-20 121832a9m88暂无昵称

    学习了

    0

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    2018-04-19 龙胆草

    学习谢谢分享

    0

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    2018-04-19 swfzhanggui

    非常好.谢谢分享

    0

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    2018-04-19 wzb521zf

    一起学习学习

    0

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    2018-04-19 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-04-19 yjs木玉

    学习学习再学习

    0

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