Baidu
map

NRR:脑梗死患者为何出现偏瘫肢体运动功能恢复不良?

2013-11-28 EurekAlert EurekAlert

磁共振检测脑梗死后运动诱发电位阴性,提示患者肢体运动功能恢复不良,并可伴有患侧大脑脚各向异性分数值及面积的改变,但其变化特点未见报道。【原文下载】 课题组以往研究显示,正常中国人大脑脚的各向异性分数值正常下限值为0.36,大脑脚面积的偏侧性下限值为0.83,这些数值的变化与肢体动能恢复的关系值得探讨。 中国南方医科大学附属小榄医院宋志彬博士所在课题组进行的一项关于“Why do stroke

磁共振检测脑梗死后运动诱发电位阴性,提示患者肢体运动功能恢复不良,并可伴有患侧大脑脚各向异性分数值及面积的改变,但其变化特点未见报道。【原文下载

课题组以往研究显示,正常中国人大脑脚的各向异性分数值正常下限值为0.36,大脑脚面积的偏侧性下限值为0.83,这些数值的变化与肢体动能恢复的关系值得探讨。

中国南方医科大学附属小榄医院宋志彬博士所在课题组进行的一项关于“Why do stroke patients with negative motor evoked potential show poor limb motor function recovery?”的研究,重点显示了磁共振诱发电位阴性时脑梗死患者患侧大脑脚各项异性分数值及面积的变化与其肢体功能恢复的关系。

结果显示,磁共振运动诱发电位阴性的脑梗死患者患侧大脑脚各向异性分数值低于临界点0.36的时间为发病后1-3个月,患侧大脑脚面积偏侧性下降低于下限值0.83的时间为病后6个月,患侧大脑脚各向异性分数值<0.36及大脑脚面积偏侧性<0.83提示偏瘫肢体运动功能恢复不良。

作者认为,研究成果揭示了磁共振运动诱发电位阴性脑梗死患者偏瘫肢体运动功能恢复不良的机制。

原文出处

Song ZB, Dang LJ, Zhou YL, Dong YJ, Liang HM, Zhu ZF, Pan SY. Why do stroke patients with negative motor evoked potential show poor limb motor function recovery? Neural Regen Res. 2013;8(29):2713-2724.【原文下载

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1980353, encodeId=ff0d19803533a, content=<a href='/topic/show?id=8afe818465f' target=_blank style='color:#2F92EE;'>#肢体运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81846, encryptionId=8afe818465f, topicName=肢体运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Tue Aug 19 02:16:00 CST 2014, time=2014-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696528, encodeId=c3861696528a0, content=<a href='/topic/show?id=2c5194149af' target=_blank style='color:#2F92EE;'>#运动功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94149, encryptionId=2c5194149af, topicName=运动功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce9629890329, createdName=doctor-chen9592, createdTime=Wed Oct 22 09:16:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465048, encodeId=18ea14650489c, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496776, encodeId=a6ff1496e7670, content=<a href='/topic/show?id=a1db2e62818' target=_blank style='color:#2F92EE;'>#偏瘫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27628, encryptionId=a1db2e62818, topicName=偏瘫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=370e9278702, createdName=fanweitanzhen, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599316, encodeId=c1ab15993163c, content=<a href='/topic/show?id=5eb4329159a' target=_blank style='color:#2F92EE;'>#功能恢复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32915, encryptionId=5eb4329159a, topicName=功能恢复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e9518693674, createdName=mnda, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1980353, encodeId=ff0d19803533a, content=<a href='/topic/show?id=8afe818465f' target=_blank style='color:#2F92EE;'>#肢体运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81846, encryptionId=8afe818465f, topicName=肢体运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Tue Aug 19 02:16:00 CST 2014, time=2014-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696528, encodeId=c3861696528a0, content=<a href='/topic/show?id=2c5194149af' target=_blank style='color:#2F92EE;'>#运动功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94149, encryptionId=2c5194149af, topicName=运动功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce9629890329, createdName=doctor-chen9592, createdTime=Wed Oct 22 09:16:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465048, encodeId=18ea14650489c, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496776, encodeId=a6ff1496e7670, content=<a href='/topic/show?id=a1db2e62818' target=_blank style='color:#2F92EE;'>#偏瘫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27628, encryptionId=a1db2e62818, topicName=偏瘫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=370e9278702, createdName=fanweitanzhen, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599316, encodeId=c1ab15993163c, content=<a href='/topic/show?id=5eb4329159a' target=_blank style='color:#2F92EE;'>#功能恢复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32915, encryptionId=5eb4329159a, topicName=功能恢复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e9518693674, createdName=mnda, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1980353, encodeId=ff0d19803533a, content=<a href='/topic/show?id=8afe818465f' target=_blank style='color:#2F92EE;'>#肢体运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81846, encryptionId=8afe818465f, topicName=肢体运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Tue Aug 19 02:16:00 CST 2014, time=2014-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696528, encodeId=c3861696528a0, content=<a href='/topic/show?id=2c5194149af' target=_blank style='color:#2F92EE;'>#运动功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94149, encryptionId=2c5194149af, topicName=运动功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce9629890329, createdName=doctor-chen9592, createdTime=Wed Oct 22 09:16:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465048, encodeId=18ea14650489c, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496776, encodeId=a6ff1496e7670, content=<a href='/topic/show?id=a1db2e62818' target=_blank style='color:#2F92EE;'>#偏瘫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27628, encryptionId=a1db2e62818, topicName=偏瘫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=370e9278702, createdName=fanweitanzhen, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599316, encodeId=c1ab15993163c, content=<a href='/topic/show?id=5eb4329159a' target=_blank style='color:#2F92EE;'>#功能恢复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32915, encryptionId=5eb4329159a, topicName=功能恢复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e9518693674, createdName=mnda, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
    2013-11-30 karmond
  4. [GetPortalCommentsPageByObjectIdResponse(id=1980353, encodeId=ff0d19803533a, content=<a href='/topic/show?id=8afe818465f' target=_blank style='color:#2F92EE;'>#肢体运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81846, encryptionId=8afe818465f, topicName=肢体运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Tue Aug 19 02:16:00 CST 2014, time=2014-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696528, encodeId=c3861696528a0, content=<a href='/topic/show?id=2c5194149af' target=_blank style='color:#2F92EE;'>#运动功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94149, encryptionId=2c5194149af, topicName=运动功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce9629890329, createdName=doctor-chen9592, createdTime=Wed Oct 22 09:16:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465048, encodeId=18ea14650489c, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496776, encodeId=a6ff1496e7670, content=<a href='/topic/show?id=a1db2e62818' target=_blank style='color:#2F92EE;'>#偏瘫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27628, encryptionId=a1db2e62818, topicName=偏瘫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=370e9278702, createdName=fanweitanzhen, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599316, encodeId=c1ab15993163c, content=<a href='/topic/show?id=5eb4329159a' target=_blank style='color:#2F92EE;'>#功能恢复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32915, encryptionId=5eb4329159a, topicName=功能恢复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e9518693674, createdName=mnda, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1980353, encodeId=ff0d19803533a, content=<a href='/topic/show?id=8afe818465f' target=_blank style='color:#2F92EE;'>#肢体运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81846, encryptionId=8afe818465f, topicName=肢体运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Tue Aug 19 02:16:00 CST 2014, time=2014-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696528, encodeId=c3861696528a0, content=<a href='/topic/show?id=2c5194149af' target=_blank style='color:#2F92EE;'>#运动功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94149, encryptionId=2c5194149af, topicName=运动功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ce9629890329, createdName=doctor-chen9592, createdTime=Wed Oct 22 09:16:00 CST 2014, time=2014-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465048, encodeId=18ea14650489c, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496776, encodeId=a6ff1496e7670, content=<a href='/topic/show?id=a1db2e62818' target=_blank style='color:#2F92EE;'>#偏瘫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27628, encryptionId=a1db2e62818, topicName=偏瘫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=370e9278702, createdName=fanweitanzhen, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599316, encodeId=c1ab15993163c, content=<a href='/topic/show?id=5eb4329159a' target=_blank style='color:#2F92EE;'>#功能恢复#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32915, encryptionId=5eb4329159a, topicName=功能恢复)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1e9518693674, createdName=mnda, createdTime=Sat Nov 30 08:16:00 CST 2013, time=2013-11-30, status=1, ipAttribution=)]
    2013-11-30 mnda

相关资讯

Stroke:糖尿病、入院血糖较高与卒中溶栓后转归较差相关

糖尿病及入院血糖对卒中溶栓后转归是否存在不利作用尚不清楚。为此,法国巴黎Bichat大学医院神经内科与卒中中心的Jean-PhilippeDesilles博士等进行了一项研究,研究结果在线发表在2013年5月23日的Stroke杂志上。研究结果显示:入院血糖高及糖尿病史与溶栓后临床转归差相关。入院血糖可以作为脑梗死严重程度的替代标志物。 该研究是一项患者注册及系统回归分析。研究人员分析来自患者注

Stroke:严重前循环脑梗死患者进行静脉tPA治疗显著改善临床预后

研究要点: 1.该研究是前瞻性研究。 2.证实tPA溶栓能够改善严重前循环梗塞患者的临床结局。 3.研究中融合了CTA信息与神经检查结果。 使用组织纤溶酶原激活物(tPA)静脉溶栓治疗严重前循环大面积缺血性卒中对患者结局的影响尚不清楚。为此,美国麻省总医院影像科的R. Gilberto González博士等人进行了一项研究,研究结果在线发表在2013年9月3日的Stroke杂志上。研

Stroke:天坛医院研发新量表用于预测脑梗死后相关院内肺炎

天坛医院研发了新的卒中相关肺炎预测量表 急性缺血性卒中常导致患者吞咽困难、进食呛咳、肢体瘫痪卧床,易发生肺部感染。为此,天坛医院的王拥军教授等人进行了一项研究,研发一种新的风险评分(急性缺血性卒中相关肺炎评分AIS-APS)用以预测急性缺血性卒中住院患者出现卒中相关肺炎的风险,并加以验证。研究结果在线发表在2013年3月12日的Stroke杂志上。研究结果显示:AIS-APS是预测急性缺血性

不要忽视腔隙性脑梗死

腔隙性脑梗死是脑梗死的一种特殊类型,是在高血压、动脉硬化的基础上,大脑深部的小支动脉发生病变,最终形成血栓或微栓塞导致血管闭塞,形成腔隙性软化病灶。其病变范围一般为2~20毫米,其中以2~4毫米者最为多见。首都医科大学与北京大学公共卫生学院研究人员对我国北方有症状的腔隙性脑梗死研究结果表明,我国北方地区腔隙性脑梗死的发病率为78/10万,我国腔隙性脑梗死在全部脑梗死和缺血性梗死中所占的比例分别为2

TIA与脑梗死,非此即彼?

  1例患者反复发作偏身肢体无力,每次症状持续时间仅为数分钟。门诊磁共振成像检查(MRI)发现对侧大脑中动脉严重狭窄,相应供血区有少量小的新鲜梗死灶。入院时患者仍有相关症状发作。   临床医生在开立入院诊断时,常常会陷入这样一种困惑:到底是诊断短暂性脑缺血发作(TIA),还是脑梗死?   理论回顾   TIA的概念诞生于上个世纪中叶。   1965年,美国第四届普林斯顿脑血管病会议

NRR:高尔基体阻断剂是治疗脑梗死的新希望

  研究发现在脑梗死常见危险因素中,多伴有患者血清sCD40L水平增高。血中sCD40L约95%来自活化血小板,但目前CD40L由血小板内转移至胞膜并释放的具体途径还不清楚。高尔基体是否参与了血小板CD40L的表达尚需证实。中南大学湘雅二医院卢伟博士及其同事的一项研究发现:急性脑梗死后血小板高尔基体的形态变化与血小板活化后合成和分泌功能增强有关。高尔基体可能参与了血小板CD40L的合成和转

Baidu
map
Baidu
map
Baidu
map