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JAHA:低盐高钾饮食对动脉僵度和左心室功能的影响

2021-12-08 MedSci原创 MedSci原创

该研究的结果表明,限制钠盐可能不会改变动脉和左室硬度。但有必要进行纵向研究以阐明饮食对动脉和左心室功能的影响。

限钠饮食是可改善血压、动脉僵硬度和左心室舒张功能潜在的非药物策略。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员调查了与年龄相关的左心室结构和功能差异,以及评估保持传统生活方式(包括低盐和高钾饮食)的土著巴布亚人左心室功能与中心血流动力学之间的关系。

研究人员通过超声心动图和多普勒成像测量了受试者的左心室大小、二尖瓣血流量和二尖瓣环组织速度。研究人员使用自动血压计(欧姆龙)测量了血压和臂踝脉搏波速度,并通过示波法(Mobil-O-Graph,使用欧洲校准)估计了受试者中心血压和波反射参数。

该研究共纳入了82名巴布亚本地人(中位年龄为42岁;38名女性;未接受血压治疗)。年龄相关的臂收缩压差异不大但显著,臂踝脉搏波速度随年龄显著增加;然而,左心室质量指数保持不变。左心室射血分数和整体纵向应变正常;二尖瓣A波速度和平均E/e´增加;e´和E/A随年龄增长而下降。臂踝脉搏波速度和尿Na/K与E/e´呈正相关且独立相关。年龄和心率与E/A呈负相关。总之,左室收缩功能正常;然而,巴布亚人的左心室舒张功能随着年龄的增长而下降。此外,与年龄相关的动脉硬化,而不是波反射,与左心室舒张功能呈负相关。

由此可见,该研究的结果表明,限制钠盐可能不会改变动脉和左室硬度。但有必要进行纵向研究以阐明饮食对动脉和左心室功能的影响。

原始出处:

Akio Ishida,et al.Effects of a Low‐Salt and High‐Potassium Diet on Arterial Stiffness and Left Ventricular Function in Indigenous Papuans.JAHA.2021.https://www.ahajournals.org/doi/full/10.1161/JAHA.121.021789

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    2021-12-10 zhaohui6731
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    2021-12-08 医鸣惊人

    认真学习了。

    0

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