Baidu
map

“头晕伴行走不稳3小时”入院,这例病因却有点特别

2018-06-01 医学界神经病学频道 火眼金睛

患者,男性,48岁,急性起病;身高1.72m,体重65.0kg。因“被发现头晕伴行走不稳3小时”入院。

病例简介

患者,男性,48岁,急性起病;身高1.72m,体重65.0kg。因“被发现头晕伴行走不稳3小时”入院。

患者3小时前起床时被发现头晕,行走不稳,口齿不清,伴大汗,卧床休息后不能缓解,家属送至本院急诊予行头颅CT+CTA示基底动脉闭塞,经家属同意后行急诊取栓治疗。

入院第二天患者神志清,吞咽无呛咳,口齿清楚,四肢肌力5级,共济运动正常,双巴士征阴性,无明显后遗症。既往有溃疡性结肠炎病史4年服用美沙拉嗪,否认高血压糖尿病、高血脂等系统疾病史。

入院查体:T 36.4℃,P 65次/分,R 14次/分,Bp 103/69mmHg。

意识嗜睡,对答切题,中度构音障碍,左瞳3.0mm,对光反射灵敏,右瞳3.0mm,对光反射灵敏,眼球运动自如,眼球震颤无,额纹对称,鼻唇沟对称,伸舌居中;

肌力:左侧肢体4级,右侧肢体4级,肌张力:正常,浅感觉:不配合,指鼻试验:两侧不稳,巴氏征:双侧阳性,双肺呼吸音清晰,对称,未闻及干湿性啰音,腹平坦,心脏听诊大致正常,吞水试验+。

辅助检查:本院头颅CT未见明显异常,一站式CT示基底动脉闭塞。

诊断:① 脑梗死(基底动脉闭塞);② 溃疡性结肠炎


图1.CTA是基底动脉闭塞




图2、3示术后DWI示残留少部分两侧小脑梗死

■ 讨论

本例诊断明确,发生脑梗塞考虑栓塞,病因通常为心源性为主或动脉到动脉栓塞,而本例为中年男性,既往无高血压,无糖尿病、无高血脂等危险因素,心脏超声未见栓子,但患者有反复腹泻病史在消化科住院确诊为溃疡性结肠炎服用美沙拉嗪。溃疡性结肠炎(UC)病因至今仍不明。

基因因素可能具有一定地位。有认为是一种自身免疫性疾病。表现可有许多形式。血性腹泻是最常见的早期症状。其他症状依次有腹痛、便血、体重减轻、里急后重、呕吐等。并发脑血管血栓栓塞较少见,国外文献报道指出在UC患者中存在严重的、致命的血栓栓塞,特别是在年轻的活动性UC患者中,但报道例数不多。其发生机制考虑与UC所致的血液高凝状态有关。包括凝血因子活性增加、纤维蛋白原增多、血小板的激活和聚集等。

有研究结果显示,血小板及D-二聚体的升高可以预测血液的高凝状态,而本例UC病人血小板及D-二聚体均正常,提示需寻找更有价值的预测因子。

就溃疡性结肠炎本身治疗:
? 卧床休息同时要注意蛋白质的补充,改善全身营养状况;

? 有贫血者可予输血,胃肠道摄入时应尽量避免牛奶和乳制品;

? 药物治疗;

①柳氮磺胺吡啶水杨酸制剂是主要治疗药物。

②皮质类固醇常用药为强的松或地塞米松,但目前并不认为长期激素维持可防止复发。在急性发作期亦可用氢化考的松或地塞米松静脉滴注,以及每晚用氢化考的松加于生理盐水中作保留灌肠,在急性发作期应用激素治疗的价值是肯定的。

炎症性肠病发生脑栓塞疾病如果没有并发活动性出血或非大量出血推荐给予抗凝治疗,可应用低分子肝素或少剂量普通肝素预防血栓形成,疗程需持续到缓解期后3个月。

使用肝素类药物的风险和不确定性,有文献报道可选择新型抗凝药物。但新型抗凝治疗UC尚需要进一步临床验证。

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1284818, encodeId=f79c128481850, content=<a href='/topic/show?id=16134436817' target=_blank style='color:#2F92EE;'>#头晕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44368, encryptionId=16134436817, topicName=头晕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Sun Jun 03 01:36:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320582, encodeId=144f32058280, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri Jun 01 16:13:09 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320535, encodeId=89d5320535e6, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jun 01 11:38:45 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320534, encodeId=783632053474, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Jun 01 11:18:52 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320533, encodeId=bd5032053325, content=关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/11/eb1f237032e0bf07b10833fc3722e645.jpg, createdBy=2fed2145219, createdName=紫迎馨, createdTime=Fri Jun 01 11:16:05 CST 2018, time=2018-06-01, status=1, ipAttribution=)]
    2018-06-03 sjzlzc007
  2. [GetPortalCommentsPageByObjectIdResponse(id=1284818, encodeId=f79c128481850, content=<a href='/topic/show?id=16134436817' target=_blank style='color:#2F92EE;'>#头晕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44368, encryptionId=16134436817, topicName=头晕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Sun Jun 03 01:36:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320582, encodeId=144f32058280, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri Jun 01 16:13:09 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320535, encodeId=89d5320535e6, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jun 01 11:38:45 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320534, encodeId=783632053474, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Jun 01 11:18:52 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320533, encodeId=bd5032053325, content=关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/11/eb1f237032e0bf07b10833fc3722e645.jpg, createdBy=2fed2145219, createdName=紫迎馨, createdTime=Fri Jun 01 11:16:05 CST 2018, time=2018-06-01, status=1, ipAttribution=)]
    2018-06-01 张新亮1853311252142e2fm

    好文献学习了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1284818, encodeId=f79c128481850, content=<a href='/topic/show?id=16134436817' target=_blank style='color:#2F92EE;'>#头晕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44368, encryptionId=16134436817, topicName=头晕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Sun Jun 03 01:36:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320582, encodeId=144f32058280, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri Jun 01 16:13:09 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320535, encodeId=89d5320535e6, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jun 01 11:38:45 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320534, encodeId=783632053474, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Jun 01 11:18:52 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320533, encodeId=bd5032053325, content=关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/11/eb1f237032e0bf07b10833fc3722e645.jpg, createdBy=2fed2145219, createdName=紫迎馨, createdTime=Fri Jun 01 11:16:05 CST 2018, time=2018-06-01, status=1, ipAttribution=)]
    2018-06-01 天地飞扬

    了解一下.谢谢分享!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1284818, encodeId=f79c128481850, content=<a href='/topic/show?id=16134436817' target=_blank style='color:#2F92EE;'>#头晕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44368, encryptionId=16134436817, topicName=头晕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Sun Jun 03 01:36:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320582, encodeId=144f32058280, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri Jun 01 16:13:09 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320535, encodeId=89d5320535e6, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jun 01 11:38:45 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320534, encodeId=783632053474, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Jun 01 11:18:52 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320533, encodeId=bd5032053325, content=关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/11/eb1f237032e0bf07b10833fc3722e645.jpg, createdBy=2fed2145219, createdName=紫迎馨, createdTime=Fri Jun 01 11:16:05 CST 2018, time=2018-06-01, status=1, ipAttribution=)]
    2018-06-01 183****7028

    学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1284818, encodeId=f79c128481850, content=<a href='/topic/show?id=16134436817' target=_blank style='color:#2F92EE;'>#头晕#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44368, encryptionId=16134436817, topicName=头晕)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Sun Jun 03 01:36:00 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320582, encodeId=144f32058280, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri Jun 01 16:13:09 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320535, encodeId=89d5320535e6, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Jun 01 11:38:45 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320534, encodeId=783632053474, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Fri Jun 01 11:18:52 CST 2018, time=2018-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=320533, encodeId=bd5032053325, content=关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/11/eb1f237032e0bf07b10833fc3722e645.jpg, createdBy=2fed2145219, createdName=紫迎馨, createdTime=Fri Jun 01 11:16:05 CST 2018, time=2018-06-01, status=1, ipAttribution=)]
    2018-06-01 紫迎馨

    关注

    0

相关资讯

肺和脑,炎或癌?——除了开颅,抗菌抉择同样艰难

1月余前无明显诱因下偶出现头晕伴视物模糊、记忆力下降,无视物旋转、黑曚、晕厥,否认发热、咳嗽咳痰、胸闷气急、恶心呕吐、消瘦等。

走出头晕与眩晕诊断的误区

头晕和眩晕是临床最常见症候,是门、急诊就诊最多的疾患之一。但众多临床医师对头晕和眩晕的概念和诊断却并不能准确把握,也很少更新有关头晕相关的临床新知,还沿用过去的概念与诊疗思路。这就是为什么常见到的头晕或眩晕症候最多使用的诊断是“颈性头晕”或“颈性眩晕”、“脑供血不足”或“椎基底动脉供血不足”、梅尼埃病,连患者本人也会像大多数医生一样给自己冠以颈性头晕/眩晕(认为与颈椎病有关)或椎基底动脉脑供血

PLoS Med:中年人站起身头晕或预示痴呆症风险高

美国研究人员发现,站起身时头晕的中年人未来患上痴呆症的风险比其他人高约40%。

警惕!动不动就头晕,可能是这些病在作祟!

一般人都会有头晕的经历,比如劳累过度,头晕乏力。但有些头晕却不能忽视,如出现相关症状需要及时到医院就诊。

张歆艺指责医生打止晕针治疗头晕到底对不对?

12月12日傍晚,张歆艺更博称自己头晕急诊时,遇医生不问情况直接打止晕针,十分无奈。微博发出后,引发网友两极争议,小编暂且不论孰是孰非,先来科普一下什么情况下应该打止晕针吧?眩晕是患者主观地感觉到自己在转动(称为主观性眩晕),或者感觉到周围的物体在围绕自己转动(称为客观性眩晕),常伴有平衡能力的丧失。如果眩晕的症状表现轻微,则可自行选择抗眩晕作用的非处方药来消除或缓解。医生给张歆艺使用的止晕针是非

夏天头晕就是中暑?帮你分清这些“假中暑”

过了夏至,气温飙升,尽管几番大雨,依然是“我和烤肉之间,只差一撮孜然”的季节了。发烧、头晕、恶心、呕吐、腹泻……有这些症状,您会不会第一反应就是自己中暑了?北京地坛医院急诊科主任马剡芳提醒,一到夏天,很多人出现上面的症状就会想到“我是不是中暑了?”其实,您很有可能是“假中暑”了!不少疾病早期的症状跟中暑比较像,难以区分。“假中暑”与“真心梗”说起“假中暑”这事儿,最严重、最危险让人后怕的,那就是急

Baidu
map
Baidu
map
Baidu
map