Heart：术前肾功能不全与TAVI患者转归差相关

2015-02-05 高晓方译医学论坛网

英国一项研究表明，在接受经导管主动脉瓣置入术(TAVI)的患者中，术前肾功能不全与包括死亡在内的转归恶化具有相关性。论文1月12日在线发表于《心脏》(Heart)。此项研究利用TAVI登记系统前瞻性采集了3980例患者的相关数据和临床转归资料，并评估了肾功能不全与TAVI后患者转归的相关性。结果显示，205例(5.5%)患者在住院期间死亡。即便对危险因素进行校正之后，中、重度慢

英国一项研究表明，在接受经导管主动脉瓣置入术(TAVI)的患者中，术前肾功能不全与包括死亡在内的转归恶化具有相关性。论文1月12日在线发表于《心脏》(Heart)。

此项研究利用TAVI登记系统前瞻性采集了3980例患者的相关数据和临床转归资料，并评估了肾功能不全与TAVI后患者转归的相关性。

结果显示，205例(5.5%)患者在住院期间死亡。即便对危险因素进行校正之后，中、重度慢性肾病(CKD)与死亡率升高仍具有显著相关性(P=0.04)。eGFR每降低10 mL/min/1.73 m²，院内死亡率升高8.2%。

在随访期间死亡的1119例患者中，即使是校正危险因素后，中、重度CKD (eGFR <45 mL/min/1.73 m²)与死亡率升高显著相关;eGFR每降低10 mL/min/1.73 m²，累积死亡率升高4.4%。术前生功能和术后透析需要可预测临床转归。

原始出处：

Ferro CJ1, Chue CD1, de Belder MA2, Moat N3, Wendler O4, Trivedi U5, Ludman P1, Townend JN1; On behalf of the UK TAVI Steering group and the National Institute for Cardiovascular Outcomes Research.Impact of renal function on survival after transcatheter aortic valve implantation (TAVI): an analysis of the UK TAVI registry.Heart. 2015 Jan 12. pii: heartjnl-2014-307041. doi: 10.1136/heartjnl-2014-307041. [Epub ahead of print]

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2015-02-11 yese

#肾功能#

83 0
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2015-02-17 chinayinhan

已阅

169 0
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2015-02-16 windmilL1989

已阅

184 0
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2015-02-15 午夜星河

好好好

166 0
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2015-02-07 jiangjun073

#肾功能不全#

67 0
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2015-02-07 zhaojie88

#ART#

73 0
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2015-02-07 爆笑小医

#HEART#

68 0

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