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Sci Rep:基于过氧化氢光解的辅助疗法可有效治疗中重度牙周炎

2017-11-04 MedSci MedSci原创

采用牙周非手术疗法治疗严重的牙周炎的效果并不理想。本研究旨在评估基于过氧化氢(H2O2)光解的抗菌化学疗法联合根面平整术(RD)治疗中重度牙周炎的临床疗效。采用随机对照试验研究设计,纳入了53名患者的142颗患者进行研究。将测试牙齿随机分配到三个处理组:组1,RD + H2O2光解;组2,RD+局部药物应用(派力奥);组3,仅RD。治疗后进行临床和微生物学检查直至第12周。结果显示,每次治疗期间检

采用牙周非手术疗法治疗严重的牙周炎的效果并不理想。本研究旨在评估基于过氧化氢(H2O2)光解的抗菌化学疗法联合根面平整术(RD)治疗中重度牙周炎的临床疗效。

采用随机对照试验研究设计,纳入了53名患者的142颗患者进行研究。将测试牙齿随机分配到三个处理组:组1,RD + H2O2光解;组2,RD+局部药物应用(派力奥);组3,仅RD。治疗后进行临床和微生物学检查直至第12周。

结果显示,每次治疗期间检查牙周袋深度(PPD)和探查出血(BoP)发现均得到改善。第12周时,第1组的PPD明显低于其他组,不过BoP第1组与其他组间没有明显差异。组1牙龈卟啉单胞菌的计数明显低于组3,与组2相当。

因此,该研究结果表明,H2O2光解治疗可用作牙周非手术治疗新的辅助性抗微生物化学疗法。

原始出处:

Taro Kanno, Keisuke Nakamura, et al., Adjunctive antimicrobial chemotherapy based on hydrogen peroxide photolysis for non-surgical treatment of moderate to severe periodontitis: a randomized controlled trial. Sci Rep. 2017; 7: 12247. Published online 2017 Sep 25. doi: 10.1038/s41598-017-12514-0

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    2017-11-05 飛歌

    学习了很有用不错

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