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Diabetes Obes Metab:抗生素使用会增加糖尿病风险吗?

2017-12-06 佚名 Medicalxpress

根据11月20日在线发表在《Diabetes Obesity and Metabolism》杂志上的一项研究,以前的研究结果显示,全身使用抗生素会增加糖尿病的风险,这可能实际上可以用临床和生活方式的因素来解释。

根据11月20日在线发表在《Diabetes Obesity and Metabolism》杂志上的一项研究,以前的研究结果显示,全身使用抗生素会增加糖尿病的风险,这可能实际上可以用临床和生活方式的因素来解释。

加拿大艾伯塔大学的Ming Ye博士及其同事在加拿大使用相关的行政健康记录评估了加拿大一队成人(1,676例糖尿病病例和13,401例对照)中抗生素的全身使用和糖尿病风险之间的关系(2000年至2015年)和艾伯塔省“明日计划”的数据,这是一项纵向队列研究。

研究人员发现,虽然有更多的病例比对照组接受了至少6个疗程的抗生素治疗(17.9%比13.8%),但当临床和生活方式因素考虑在内时,抗生素使用和糖尿病风险之间的联系逐渐减少。调整后的方案结果显示,与接受抗生素治疗0或1个疗程的患者相比,接受更多抗生素治疗的患者糖尿病风险并没有明显增加(接受2~4种抗生素:OR= 0.97(0.83-1.13);> = 5种时OR=0.98(0.82-1.18))。

作者总结说:“我们的研究结果表明,以前通过行政记录的研究所得到的那些提示相关的联系可能需要重新认识了。”

原始出处:Ming Ye , Paula J. Robson , Dean T. Eurich ,et al. Systemic Use of Antibiotics and Risk of Diabetes in Adults: A Nested Case-control Study of Alberta's Tomorrow Project. Diabetes Obesity and Metabolism , 2017

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objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:02:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2018-06-02 guojianrong
  5. 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  6. 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content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Dec 09 07:21:48 CST 2017, time=2017-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267276, encodeId=c99a26e27676, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Dec 06 14:13:12 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267268, encodeId=cf9726e2688a, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:02:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2018-02-28 爆笑小医
  7. 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objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:02:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2017-12-10 131****1460

    学习了受益匪浅

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:02:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2017-12-09 1209e435m98(暂无昵称)

    学习了.谢谢分享!

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1901877, encodeId=cda919018e7f1, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Thu Feb 15 09:52:00 CST 2018, time=2018-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685154, encodeId=bea916851548c, content=<a href='/topic/show?id=9bc05542024' target=_blank style='color:#2F92EE;'>#抗生素使用#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55420, encryptionId=9bc05542024, topicName=抗生素使用)], attachment=null, authenticateStatus=null, createdAvatar=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Wed Feb 28 20:52:00 CST 2018, time=2018-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268364, encodeId=02852683644c, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Dec 10 13:00:37 CST 2017, time=2017-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=268003, encodeId=2ded26800324, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Dec 09 07:21:48 CST 2017, time=2017-12-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267276, encodeId=c99a26e27676, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Dec 06 14:13:12 CST 2017, time=2017-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267268, encodeId=cf9726e2688a, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Wed Dec 06 14:02:54 CST 2017, time=2017-12-06, status=1, ipAttribution=)]
    2017-12-06 131****1460

    学习了受益匪浅

    0

  10. 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    2017-12-06 Y—xianghai

    学习了新知识

    0

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