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每日病例丨当结膜炎、尿道炎、关节炎同时发生时,你想到了什么

2017-11-02 MedSci MedSci原创

今天的病例是一例以关节炎、眼及皮肤黏膜损害、尿道炎为主要表现的一组临床综合征。

今天的病例是一例以关节炎、眼及皮肤黏膜损害、尿道炎为主要表现的一组临床综合征。

病史:

患者为一位11岁的男孩,在半个月前随父母去内蒙古草原旅行,在骑马时在马背受到颠簸后于夜间出现排尿疼痛。

间隔1天,患儿可疑扭伤后左踝关节出现肿痛,同时双眼结膜出现充血,有少许淡黄色分泌物。先后就诊于当地医院,分别考虑“泌尿系统感染、结膜炎”,给予对症治疗,疗效欠佳。

10天前出现发热,体温37.5~39.3℃,同时出现腹泻,为黏液便,伴里急后重,外院考虑“痢疾”,给予抗感染治疗5天,腹泻症状消失,尿痛略减轻,结膜充血十余日消失。左踝关节仍肿痛明显,骨科考虑“骨质板损伤”,给予夹板固定。但仍持续发热,遂来我院就诊。

患儿既往无特殊病史。父母体健,家族无强直性脊柱炎、类风湿性关节炎等病史。

查体:

患者全身皮肤黏膜无皮疹及出血点,皮肤无破损,全身浅表淋巴结无肿大,结膜无充血,咽部充血,双侧扁桃体无肿大。尿道口略红肿,无破溃,有少许黏液性分泌物。腹平软,无压痛,无压痛,移动性浊音(-),肠鸣音正常。双肺呼吸音清晰,未闻及干、湿性啰音。心前区无隆起及凹陷,心界无扩大,心率106次/分,节律规则,各瓣膜听诊区均未闻及病理性杂音。

辅助检查:

磁共振:胫骨后肌、趾长屈肌及拇长屈肌略肿胀,提示左小腿多发肌挫伤。

血常规:白细胞计数12.4 10^9/L、血红蛋白101 g/L、血小板计数242 10^9/L

大生化:丙氨酸转氨酶120 U/L、门冬氨酸氨基转移酶43 U/L、谷氨酰转肽酶107 U/L U/L、C反应蛋白(CRP)57.1 mg/L

红细胞沉降率:92 mm/h

免疫球蛋白:IgG 19.1 g/L、IgA 4.35 g/L、IgM 1.28 g/L、类风湿因子阴性

抗核抗体:阴性

PPD:阴性

肥大反应:阴性

冷凝集试验:阴性

尿常规:WBC (+~+++)

骨髓穿刺涂片:未见异常

人类白细胞抗原B27(HLA-B27):阳性

简介:

该病在遗传背景下感染诱发的免疫失调引起。成年男性多见,儿童、妇女、老人发病少见。儿童中也是男性发病率高,常发病于6—9月份。以性传播型和痢疾型为主。儿童多见于肠道感染(痢疾)后发病,肠道细菌感染后获得痢疾型,主要是志贺菌属、沙门菌属、耶尔森菌属以及弯曲杆菌属等感染。

欲知详细诊断及解析,请查看【梅斯医生】——风湿免疫科病例:尿痛半个月,发热10天。

更多点评分析,趣味的学习,详情尽在梅斯医生上,您可以在这里体验模拟诊疗


下载链接http://www.bioon.com/index_forword.asp?id=9277

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    2018-07-30 lifestar
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    2017-11-04 lmm397
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1769116, encodeId=0ea21e6911615, content=<a href='/topic/show?id=ebef4e52844' target=_blank style='color:#2F92EE;'>#尿道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47528, encryptionId=ebef4e52844, topicName=尿道)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b63c37986505, createdName=lifestar, createdTime=Mon Jul 30 17:42:00 CST 2018, time=2018-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677490, encodeId=0fd716e7490c8, content=<a href='/topic/show?id=2ebbe881920' target=_blank style='color:#2F92EE;'>#结膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78819, encryptionId=2ebbe881920, topicName=结膜炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=803827523485, createdName=tm10051990, createdTime=Thu Feb 01 14:42:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265562, encodeId=72dd126556230, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623104, encodeId=09a216231042a, content=<a href='/topic/show?id=504b4e543f3' target=_blank style='color:#2F92EE;'>#尿道炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47543, encryptionId=504b4e543f3, topicName=尿道炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258427, encodeId=225c25842e06, content=学习学习.了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Nov 03 20:16:39 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258221, encodeId=3cce258221b1, content=学习学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Nov 03 05:24:17 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258164, encodeId=3a9825816443, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Nov 02 22:38:43 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
    2017-11-03 1dd8c52fm63(暂无匿称)

    学习学习.了解了解

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1769116, encodeId=0ea21e6911615, content=<a href='/topic/show?id=ebef4e52844' target=_blank style='color:#2F92EE;'>#尿道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47528, encryptionId=ebef4e52844, topicName=尿道)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b63c37986505, createdName=lifestar, createdTime=Mon Jul 30 17:42:00 CST 2018, time=2018-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677490, encodeId=0fd716e7490c8, content=<a href='/topic/show?id=2ebbe881920' target=_blank style='color:#2F92EE;'>#结膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78819, encryptionId=2ebbe881920, topicName=结膜炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=803827523485, createdName=tm10051990, createdTime=Thu Feb 01 14:42:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265562, encodeId=72dd126556230, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623104, encodeId=09a216231042a, content=<a href='/topic/show?id=504b4e543f3' target=_blank style='color:#2F92EE;'>#尿道炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47543, encryptionId=504b4e543f3, topicName=尿道炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258427, encodeId=225c25842e06, content=学习学习.了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Nov 03 20:16:39 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258221, encodeId=3cce258221b1, content=学习学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Nov 03 05:24:17 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258164, encodeId=3a9825816443, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Nov 02 22:38:43 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
    2017-11-03 jihuaijun1112

    学习学习学习学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1769116, encodeId=0ea21e6911615, content=<a href='/topic/show?id=ebef4e52844' target=_blank style='color:#2F92EE;'>#尿道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47528, encryptionId=ebef4e52844, topicName=尿道)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b63c37986505, createdName=lifestar, createdTime=Mon Jul 30 17:42:00 CST 2018, time=2018-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677490, encodeId=0fd716e7490c8, content=<a href='/topic/show?id=2ebbe881920' target=_blank style='color:#2F92EE;'>#结膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78819, encryptionId=2ebbe881920, topicName=结膜炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=803827523485, createdName=tm10051990, createdTime=Thu Feb 01 14:42:00 CST 2018, time=2018-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265562, encodeId=72dd126556230, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623104, encodeId=09a216231042a, content=<a href='/topic/show?id=504b4e543f3' target=_blank style='color:#2F92EE;'>#尿道炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47543, encryptionId=504b4e543f3, topicName=尿道炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sat Nov 04 09:42:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258427, encodeId=225c25842e06, content=学习学习.了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Fri Nov 03 20:16:39 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258221, encodeId=3cce258221b1, content=学习学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Nov 03 05:24:17 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258164, encodeId=3a9825816443, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Nov 02 22:38:43 CST 2017, time=2017-11-02, status=1, ipAttribution=)]
    2017-11-02 天涯183

    非常好的文章.学习了

    0

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