Diabetic Med：1型糖尿病患者的无症状性低血糖：发病率和危险因素

2019-03-26 不详网络

<span style="font-size:9.0pt;font-family:宋体;mso-ascii-theme-font:major-fareast; mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:major-fareast; color:black;mso-bidi-font-weight:bold">近日，国际杂

近日，国际杂志《Diabetic Med》上在线发表一项关于1型糖尿病患者的无症状性低血糖：发病率和危险因素的研究。

目前尚无研究充分描述无症状低血糖的流行病学。研究人员调查了1型糖尿病患者无症状性低血糖的发病率和危险因素。

一组153名患有1型糖尿病的人参加了6天的盲法连续血糖监测（CGM）和记录低血糖症状。在进入研究时，将低血糖意识分类（通过三种不同的方法）并测量HbA 1c和C-肽。低血糖发作定义为间质葡萄糖≤3.9mmol / l（IG 3.9）或≤3.0mmol/l（IG 3.0）≥15min，如果未报告低血糖症状，则认为无症状。

在阈值IG 3.9和IG 3.0，低血糖发作的发生率分别为5.0（7.9）[中位数（IQR）]和1.3（3.4）发作/人 - 周。四分之三的发作无症状。总共有77％和52％的参与者在IG 3.9和IG 3.0 [3.0（6.2）和1.0（2.3）无症状发作/人 - 周]中经历了一次或多次无症状性低血糖发作。在多变量分析中，意识降低与无症状性低血糖，特别是夜间活动呈正相关，与症状性低血糖呈负相关。高胰岛素剂量与无症状和症状性低血糖风险增加相关，而低HbA 1c 和糖尿病病程长，只是症状性低血糖的危险因素。

无症状性低血糖是1型糖尿病中大多数低血糖事件。低血糖意识降低和胰岛素剂量高是无症状低血糖的危险因素，但严重低血糖的其他常规危险因素与无症状发作的风险无关。

原始出处：

M. M. Henriksen ，H. U. Andersen，B. Thorsteinsson，et al. Asymptomatic hypoglycaemia in Type 1 diabetes: incidence and risk factors

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2020-01-18 millore

#1型糖尿病患者#

74 0
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2019-06-14 ms5439512287675881

#BET#

56 0
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2020-01-04 ms9608593228839890

#DIA#

67 0
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2019-08-26 lifestar

#发病率#

60 0
[GetPortalCommentsPageByObjectIdResponse(id=1968279, encodeId=282519682e901, content=<a href='/topic/show?id=a4b96e542' target=_blank style='color:#2F92EE;'>#1型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=675, encryptionId=a4b96e542, topicName=1型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0e3195, createdName=millore, createdTime=Sat Jan 18 12:35:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761029, encodeId=ebc01e6102930, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Fri Jun 14 05:35:00 CST 2019, time=2019-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639018, encodeId=a69116390189b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sat Jan 04 18:35:00 CST 2020, time=2020-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823538, encodeId=1cd2182353840, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Aug 26 04:35:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474718, encodeId=bc9b14e47187c, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Thu Mar 28 00:35:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485031, encodeId=7fad14850318a, content=<a href='/topic/show?id=4bbe5902ed2' target=_blank style='color:#2F92EE;'>#无症状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59027, encryptionId=4bbe5902ed2, topicName=无症状)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20180429/70baad2aa5a046c5aa2914d262de7d37.jpg, createdBy=bd077990475, createdName=12498da4m34(暂无昵称), createdTime=Thu Mar 28 00:35:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609655, encodeId=fcff160965580, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Mar 28 00:35:00 CST 2019, time=2019-03-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970701, encodeId=30ef19e070125, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Sat Oct 12 16:35:00 CST 2019, time=2019-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042316, encodeId=deb310423161c, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Tue Mar 26 12:35:00 CST 2019, time=2019-03-26, status=1, ipAttribution=)]
2019-03-28 xue8604

#糖尿病患者#

76 0
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2019-03-28 12498da4m34(暂无昵称)

#无症状#

68 0
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2019-03-28 ms3994565386320060

#Med#

63 0
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2019-10-12 chenzhuanggui

#Diabetic#

76 0
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2019-03-26 misszhang

谢谢MedSci提供最新的资讯

65 0

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Diabetic Med：1型糖尿病患者的无症状性低血糖：发病率和危险因素

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